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Total 442 results found since Jan 2013.
Electrospun kaolin-loaded chitosan/PEO nanofibers for rapid hemostasis and accelerated wound healing
In this study, the classic hemostatic chitosan and the most well-known inorganic hemostatic agent-kaolin were tried to combine to form a more excellent dressing. Together with the aid of non-toxic, harmless and good hydrophilic polyethylene oxide, chitosan/polyethylene oxide (PEO)/kaolin nanofiber membranes (CPKs) were prepared by electrospinning technology. Such membranes exhibited adjustable mechanical properties and good biocompatibility. Furthermore, a series of in vitro coagulation experiments proved that CPKs with 10 % ratio of kaolin (CPK10) has excellent hemostatic ability. Especially, in the whole blood coagulatio...
Source: International Journal of Biological Macromolecules - July 30, 2022 Category: Biochemistry Authors: Tao Liu Zhuoran Zhang Jiacheng Liu Peijie Dong Feng Tian Fan Li Xin Meng Source Type: research
Trace element & amp; vitamin content of Ankaferd hemostat and hepatoprotective effect
Turk J Med Sci. 2021 Nov 13. doi: 10.3906/sag-2109-30. Online ahead of print.ABSTRACT...PMID:34773687 | DOI:10.3906/sag-2109-30
Source: Turkish Journal of Medical Sciences - November 13, 2021 Category: General Medicine Authors: Beg üm Güneş Nazife Yasemin Ardi çoğlu Akişin Mehmet Nejat Akar Source Type: research
In-vitro and in-vivo hemostat evaluation of decellularized liver extra cellular matrix loaded chitosan/gelatin spongy scaffolds for liver injury
Int J Biol Macromol. 2021 Oct 25:S0141-8130(21)02286-8. doi: 10.1016/j.ijbiomac.2021.10.128. Online ahead of print.ABSTRACTIndividually, Chitosan (C) and Gelatin (G) are increasingly being used for the simulation and testing of surgical procedures. In the present study, at combination of chitosan/gelatin (CG) was optimized and later enriched by the loading decellularized liver extracellular matrix powder (dLECM) prepared from porcine liver, we hypothesized CG-dLECM combination would enhance wound healing and reduce postoperative complications after liver surgery. Varying concentration of dLECM (1, 4, and 8 mg/ml) were load...
Source: International Journal of Biological Macromolecules - October 28, 2021 Category: Biochemistry Authors: Thanh Lan Chu Garima Tripathi Bae Sang Ho Byong-Taek Lee Source Type: research
Engineered bio-inspired multifunctional peptide and protein based therapeutic biomolecules for better wound care
Chem Asian J. 2021 Oct 12. doi: 10.1002/asia.202101022. Online ahead of print.ABSTRACTDeveloping nonimmunogenic therapeutic biomolecules for facilitating blood clotting followed by wound healing via therapeutic angiogenesis, still remains a formidable challenge. Excessive blood loss of accident victims and battalions cause huge no. of deaths worldwide. Patients with inherited bleeding disorders face acute complications during injury and post-surgery. Biologically-inspired peptide-based hemostat can act as a potential therapeutic for handling coagulopathy. Additionally, non-healing wounds for patients having ischemic diseas...
Source: Chemistry, an Asian Journal - October 13, 2021 Category: Chemistry Authors: Rituparna Sinha Roy Paramita Gayen Somnath Jan Nilkanta Chowdhury Angshuman Bagchi Snehasish Ghosh Monjuri Hembram Source Type: research
Hemostatic Efficacy and Biocompatibility Evaluation of a Novel Absorbable Porous Starch Hemostat
CONCLUSION: According to our study, Ca2+CPSM could effectively achieve hemostasis in the standard rat liver injury model and exhibited good blood compatibility and in vivo tissue compatibility. These finding suggested that Ca2+CPSM as a new kind of APSH had its extensive clinical application value.PMID:34551638 | DOI:10.1177/15533506211046100
Source: Surgical Innovation - September 23, 2021 Category: Surgery Authors: Jianjun Zhu Zhuona Wu Wenzhong Sun Zhiyun Meng Xiaoxia Zhu Hui Gan Ruolan Gu Xuan Guo Guifang Dou Source Type: research
