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Total 442 results found since Jan 2013.

Polysaccharide-based (kappa carrageenan/carboxymethyl chitosan) nanofibrous membrane loaded with antifibrinolytic drug for rapid hemostasis- in vitro and in vivo evaluation
Int J Biol Macromol. 2023 Jul 12:125786. doi: 10.1016/j.ijbiomac.2023.125786. Online ahead of print.ABSTRACTThis work aimed to establish a novel membrane consisting of hemostatic polysaccharides, kappa-carrageenan (KC), and carboxymethyl chitosan (CMC) in tandem with polyvinyl alcohol that spun together as a matrix and loaded with tranexamic acid (TXA) as antifibrinolytic agent for further coagulation effect during and after oral surgeries. The electrospinning of KC was done for the first time and in comparison of CMC has better hemostatic efficacy. The effect of the hemostat was investigated by its surface morphology (SEM...
Source: International Journal of Biological Macromolecules - July 14, 2023 Category: Biochemistry Authors: Sara Salamzadeh Salmasi Morteza Ehsani Mojgan Zandi Mahdi Saeed Mike Sabeti Source Type: research

Biomimetic and Multifunctional Hemostatic Hydrogel with Rapid Thermoresponsive Gelation and Robust Wet Adhesion for Emergency Hemostasis: A Rational Design Based on Photo-Cross-Linking Coordinated Hydrophilic-Hydrophobic Balance Strategies
Biomacromolecules. 2023 Jun 27. doi: 10.1021/acs.biomac.3c00357. Online ahead of print.ABSTRACTUncontrolled bleeding in emergency situations is a great threat to both military and civilian lives, and an ideal hemostat for effectively controlling prehospital hemorrhage is urgently needed but still lacking. Although hemostatic hydrogels are promising for emergency hemostasis, they are currently challenged by either the mutual exclusion between a short gelation time and strong adhesive network or the insufficient functionality of ingredients and complicated operations for in situ curing. Herein, an extracellular matrix biopol...
Source: Biomacromolecules - June 27, 2023 Category: Biochemistry Authors: Hongyang Song Lei Xing Wentao Liu Xue Wang Zhaosheng Hou Yue Wang Zhenhao Zhang Yiming Li Tianduo Li Xiaolong Wang Hui Chen Shu Xing Jing Xu Source Type: research

The effects of Ankaferd hemostat on preventing oral mucositis in colorectal cancer patients receiving chemotherapy
ConclusionsIt was determined that Ankaferd hemostat is effective in preventing oral mucositis due to chemotherapy in adult patients diagnosed with colorectal cancer. In addition, it has been suggested to conduct new studies on the effectiveness of Ankaferd hemostat in the prevention of mucositis in different groups.Trial registrationThe study was registered at ClinicalTrials.gov (ID: NCT05438771, Date: 25.06.2022).
Source: Supportive Care in Cancer - June 8, 2023 Category: Cancer & Oncology Source Type: research

Use of hemostatic clips to reduce blood loss in between Mohs micrographic surgery stages
During Mohs micrographic surgery on the scalp, intraoperative hemostasis often requires the use of hemostats, figure-of-eight sutures, or electrosurgery. Hemostat and a figure-of-eight suture placement can be cumbersome in this location and pose difficulty in controlling diffuse bleeding,1 and electrosurgery can create a devitalized wound bed.
Source: Journal of the American Academy of Dermatology - May 10, 2023 Category: Dermatology Authors: Aaditya Kumar, Daehee Jeong, Alexandria M. Riopelle, Carl F. Schanbacher Tags: JAAD Online Source Type: research

Cancers, Vol. 15, Pages 2644: US Evaluation of Topical Hemostatic Agents in Post-Thyroidectomy
Conclusions: with equal hemostatic effectiveness, the fibrin glue pad is more favorable in the ultrasound follow-up because it creates reduced surgical outcomes. It is also important to know and recognize the ultrasound characteristics of oxidized cellulose-based hemostats in order to reduce the number of diagnostic errors and inappropriate diagnostic investigations.
Source: Cancers - May 7, 2023 Category: Cancer & Oncology Authors: Vincenzo Dolcetti Eleonora Lori Daniele Fresilli Giovanni Del Gaudio Chiara Di Bella Patrizia Pacini Vito D ’Andrea Fabrizio Maria Frattaroli Giulia Giordana Vallone Piero Liberatore Daniele Pironi Gian Luigi Canu Pietro Giorgio Cal ò Vito Cantisani Sa Tags: Article Source Type: research

An anticoagulant/procoagulant self-converting and bleeding site targeting systemic nanotherapy for rapid controlling of non-compressible bleeding without risk of thrombosis
CONCLUSIONS: PSNs is expected to be a low-cost, safe, efficient, clinically translatable first-aid hemostat for first-aid scenarios.PMID:36871669 | DOI:10.1016/j.jtha.2023.02.020
Source: Thrombosis and Haemostasis - March 5, 2023 Category: Hematology Authors: Yuchuan Yuan Jiaxing Liu Hongli Duan Chengyuan Zhang Wenxing Wu Qin Qin Jie Lou Qing Zhang Qin Wang Xiaohui Li Xing Zhou Source Type: research

The use of sealing hemostat patch (HEMOPATCH ®) in laparotomic myomectomy: a prospective case–control study
ConclusionsHEMOPATCH®, during laparotomic myomectomy, is a valid alternative solution for obtaining rapid hemostasis and consequently intraoperative and postoperative bleeding. Furthermore, we suggest that a lower inflammatory peritoneal state is probably correlated with the barrier effect of the patch on the suture.
Source: Archives of Gynecology and Obstetrics - February 15, 2023 Category: OBGYN Source Type: research

Microneedle Bandage for Hemostatic Control
Scientists at Penn State have developed a microneedle bandage that can rapidly stop bleeding. Uncontrolled bleeding following a traumatic injury is a major cause of death in the young, and developing new medical technologies that can rapidly stop ble...
Source: Medgadget - January 31, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Surgery PennState Source Type: blogs

Intraoperative ultrasound appearance of PAHACEL ® Absorbable Hemostat (oxidised regenerated cellulose) in small to medium size intraaxial lesions localization
Neurochirurgie. 2023 Jan 19;69(2):101405. doi: 10.1016/j.neuchi.2023.101405. Online ahead of print.NO ABSTRACTPMID:36680852 | DOI:10.1016/j.neuchi.2023.101405
Source: Neurochirurgie - January 21, 2023 Category: Neurosurgery Authors: C Romero-L ópez C G Butr ón J A Torri E C árdenas J Ros I Mart ín Source Type: research