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The Adaptation-Maladaptation Framework of Aging
While a great deal is known about the ways in which old tissues differ from young tissues, there remains considerable room to theorize on how exactly aging is caused and progresses. Which manifestations are causative, and which downstream consequences, which mechanisms are important, which are side-effects or diversions. Theories of aging abound, alongside frameworks intended to steer thinking about aging. We stand in the opening years of a new era of medicine, in which the first rejuvenation therapies exist or are under development, senolytics that can clear senescent cells, alongside reprogramming strategies and potentia...
Source: Fight Aging! - September 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

AI is living up to its promise as a tool for radiology
For the last few years, artificial intelligence (AI) has been proving itself as an effective tool in breast cancer screening. An ever-growing list of research studies has shown that using AI in mammography can safely and efficiently reduce patient wait times while reducing the pressure on in-demand radiologists. This is significant, as early detection greatly Read more… AI is living up to its promise as a tool for radiology originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - September 21, 2023 Category: General Medicine Authors: Tags: Tech Radiology Source Type: blogs

The Lack of Consensus on Approaches to Aging as a Flaw to be Fixed
It can be argued that the largest challenge facing the development of means to treat aging as a medical condition is that there is, as of yet, no useful consensus position on how to measure aging, how to define aging, or which of the countless measurable aspects of biochemistry that change with age are the most appropriate targets for therapy. This means that any given research group or biotech startup has a lot of leeway to argue that their approach is the right one - and it might take twenty years to establish the effects of their therapies on long-term health and life span, even given a successful development program. T...
Source: Fight Aging! - September 19, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Healthcare IT Regulations – What Needs to Be Added and What Needs to Be Removed
There are a lot of rules and regulations in place in the world of healthcare. These are put into place in order to protect patients and organizations. However, the world of healthcare is constantly changing and evolving as we come up with new ideas and solutions. Have the regulations done the same though? Or are there areas that are missing regulations? Or are there areas in healthcare where past regulations are now too restrictive and are holding us back? In search of answers to these questions, we reached out to our incredibly beautiful Healthcare IT Today Community to see what areas they would add, remove, or update re...
Source: EMR and HIPAA - September 19, 2023 Category: Information Technology Authors: Grayson Miller Tags: Administration Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC Regulations 1upHealth 4medica Amanda Heidemann Andrea Mazzoccoli Andrew Norden MD Bill Charnetski Cheryl Cheng Commur Source Type: blogs

Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Microneedle Skin Patch Measures Cancer Biomarkers
Researchers at the Harvard Wyss Institute have developed a technique that lets clinicians to characterize and monitor melanoma. The system involves using a microneedle patch that can draw deep interstitial fluid into itself through a series of penetr...
Source: Medgadget - September 14, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Diagnostics Medicine Oncology harvard wyssinstitute Source Type: blogs

Enzyme Treatment Strips Mucins from Cancer Cells
Researchers at Stanford University have developed a new type of cancer therapy. The technology targets mucins, sugar-coated proteins that help cancer cells to metastasize and avoid the immune system. In particular, mucins enable cancer cells to survi...
Source: Medgadget - September 12, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology Source Type: blogs

Bonus Features – September 10, 2023 – 77% of clinicians see RPM outpacing traditional inpatient care within five years, Microsoft partnering with Paige on pathology and oncology AI models, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News Executives for Healthcare Innovation is transferring its assets to the American Telemedicine Association, and ATA will extend engagement opportunities to current EHI members through its various Special Interest Groups. More...
Source: EMR and HIPAA - September 11, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Adrian Agostini Alo American Telemedicine Association Andrea Rowe Anki ATA AVIA Black Book Research Canopy Edifecs Experity Healthcare IT Today Bonus Features HITRUST Ibex Medical Analytics iMerit Inovalon K Source Type: blogs

The complexities of healing and faith
As a physician, there are moments during the day when you must deliver a disheartening diagnosis to your patient: pancreatic cancer, ALS, leukemia, and unfortunately, the list goes on. The patient must face the harsh realities that are now placed before him/her. Those realities, at times, leave him with a very small window of hope Read more… The complexities of healing and faith originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - September 10, 2023 Category: General Medicine Authors: Tags: Conditions Hospital-Based Medicine Source Type: blogs

Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards an Improved Suppression of Maladaptive Inflammation
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical intervention.
Source: Fight Aging! - September 7, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Q & A With Dylan Burnette: Muscle Cells, Cell Movement, and Microscopy
Courtesy of Dr. Dylan Burnette. “We scientists know very little of what can be known—I find that invigorating,” says Dylan Burnette, Ph.D., an associate professor of cell and developmental biology at Vanderbilt University School of Medicine in Nashville, Tennessee. “Most people find it exhausting, but I’m comfortable with not knowing all of biology’s secrets.” In an interview, Dr. Burnette shared his lab’s work on muscle cells, the knowledge he hopes readers take away from his research, and some advice to future scientists about being comfortable being wrong. Q: How did you first become interested in s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 6, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cellular Imaging Cellular Processes Profiles Source Type: blogs

A Discussion of Current Approaches Under Development for the Treatment of Aging
This open access paper tours a number of the present approaches under development to the treatment of aging as a medical condition, dwelling the most on therapies targeting senescent cells, either for destruction or to suppress the harmful senescence-associated secretory phenotype. We live in an exciting time of great potential, an age of accelerating progress in the capabilities of medical biotechnology, though it remains the case that too few people realize just how close we are to the widespread use of the first practical rejuvenation therapies. Aging poses one of the greatest challenges for modern medicine, as...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features – September 3, 2023 – 60% of cybersecurity incidents impact patient care, the average medical device has six or more security vulnerabilities, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Research ONC renewed its contract for The Sequoia Project to be the Recognized Coordinating Entity for TEFCA implementation. That process will involve working with seven current Qualified Health Information Network can...
Source: EMR and HIPAA - September 3, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AION Biosystems Akshay Sharma Alexander Group American Telemedicine Association Asimily ATA Atropos Health BeMe Health Carenet Health Claroty Cognizant Craig Hovda Digital Medicine Society eClinicalWorks eCW E Source Type: blogs

Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men. « Back to Top Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/ Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs