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The Top 10 Health Chatbots
This study from March 2023 reports how an app developed to help patients’ bowel preparation can increase compliance and thus, the number of successful colonoscopies.
In some cases, health chatbots are also able to connect patients with clinicians for diagnosis or treatment, but that is one step further down the line. The general idea is that in the future, these talking or texting smart algorithms might become the first contact point for primary care. Patients will not get in touch with physicians or nurses or any medical professional with every one of their health questions but will turn to chatbots first. If th...
Source: The Medical Futurist - August 1, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design health chatbot Innovation List medical Personalized medicine AI technology digital health chatbots Source Type: blogs
University of Maryland Doctor Tells Public He ' s Not Sure Smoking is Any More Hazardous than Vaping
In anarticle published today byABC News, a physician from the University of Maryland is quoted as telling the public that he isn ' t sure that smoking is any more hazardous than vaping.According to the article: "' We just cannot make a conclusion that it [vaping] is safer than cigarettes, '
said Dr. Jason Rose, a Pulmonary and Critical Care Physician who is also
the Associate Professor of Medicine and Associate Dean for Innovation& Physician Science at The University of Maryland. " Of course, stating that you ' re not sure if vaping is safer than cigarettes is equivalent to saying that you ' re not sure smo...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - July 31, 2023 Category: Addiction Source Type: blogs
Consciously Exploring Your Relationship with Drugs
Humanity has a complex, long-term relationship with a wide variety of drugs. In this article let’s delve into your personal relationship with drugs, how you frame them, and how you might upgrade these relationships to be more conscious and aligned with your path of self-development. Let’s include common drug sources like coffee, tea, and chocolate too, so this will be very inclusive.
My purpose here isn’t to encourage or discourage you from using any particular substances but rather to invite you to take a more conscious and honest look at your current frames, attitudes, biases, and behaviors, and dete...
Source: Steve Pavlina's Personal Development Blog - July 21, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Emotions Health Lifestyle Relationships Values Source Type: blogs
Psychedelic Science 2023 – Full Conference Review
In June I attended the Psychedelic Science 2023 conference at the Colorado Convention Center in Denver. We were told this was the largest psychedelic-related gathering in the history of the planet, attracting about 12,000 attendees and 500 speakers. In this post I’ll share about my experiences and insights from the conference.
Here’s a pic from inside the Bellco Theater where the main keynotes were held.
The Colorado Convention Center is sizable, and sessions were spread across many different rooms. Even though I didn’t do extra exercise on this trip, I was typically hitting about 1000 calories ...
Source: Steve Pavlina's Personal Development Blog - July 7, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Health Lifestyle Source Type: blogs
Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 29th 2023
In this study, we used a Drosophila model to understand the role of the dec2P384R mutation on animal health and elucidate the mechanisms driving these physiological changes. We found that the expression of the mammalian dec2P384R transgene in fly sleep neurons was sufficient to mimic the short sleep phenotype observed in mammals. Remarkably, dec2P384Rmutants lived significantly longer with improved health despite sleeping less. In particular, dec2P384R mutants were more stress resistant and displayed improved mitochondrial fitness in flight muscles. Differential gene expression analyses went on to reveal several altered tr...
Source: Fight Aging! - May 28, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cellular Senescence in Skin as an Early Sign of Aging
We reported that skin inherently possesses mechanisms to remove senescent cells. In the epidermis, this is achieved by the binding of JAG1, a Notch ligand expressed on adjacent non-senescent keratinocytes, to Notch1 receptors expressed by senescent keratinocytes, which promotes the exclusion of senescent cells from the basal layer by inducing differentiation. Meanwhile, in the dermis, senescent cells are phagocytosed by macrophages through recognition by the phosphatidyl serine (PS) receptor STAB1. However, since ageing is associated with the accumulation of senescent cells in skin tissue, it is hypothesized that this accu...
Source: Fight Aging! - May 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, January 16th 2023
Conclusions
Implanted Hair Follicle Cells Produce Remodeling of Scar Tissue
Assessment of Somatic Mosaicism as a Biomarker of Aging
The Gut Microbiome of Centenarians
https://www.fightaging.org/archives/2023/01/the-gut-microbiome-of-centenarians/
The state of the gut microbiome is arguably as influential on health as exercise. Various microbial species present in the gut produce beneficial metabolites, such as butyrate, or harmful metabolites, such as isoamylamine, or can provoke chronic inflammation in a variety of ways. An individual can have a better or worse microbiome, assessing these and other fu...
Source: Fight Aging! - January 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, December 5th 2022
In conclusion, the PAAIs examined (i.e. mTOR loss of function, Ghrhr loss of function, intermittent fasting-based version of dietary restriction) often influenced age-sensitive traits in a direct way and not by slowing age-dependent change. Previous studies often failed to include young animals subjected to PAAI to account for age-independent PAAI effects. However, any study not accounting for such age-independent intervention effects will be prone to overestimate the extent to which an intervention delays the effects of aging on the phenotypes studied. This can result in a considerable bias of our view on how modifiable a...
Source: Fight Aging! - December 4, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 21st 2022
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer.
The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting.
Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 7th 2022
In conclusion, the national prevalence of dementia and MCI in 2016 found in this cross-sectional study was similar to that of other US-based studies.
Clearing Microglia Reverses Age-Related Disruption of Sleeping Patterns in Mice
https://www.fightaging.org/archives/2022/11/clearing-microglia-reverses-age-related-disruption-of-sleeping-patterns-in-mice/
Microglia are innate immune cells of the central nervous system. They are analogous to macrophages in the rest of the body, but undertake additional duties relating to the function of neurons and in brain tissue. Microglia become overly active and inflamma...
Source: Fight Aging! - November 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An old interview with one of this year ’ s Nobel Chemists – Carolyn Bertozzi
This was an interview for my Personal Reactions column on the old ChemWeb site from 1999 featuring Carolyn Bertozzi, who this week was announced as one of three recipients of the 2022 Nobel Prize in Chemistry.
Biography: Professor Carolyn Ruth Bertozzi, born 10th October 1966. Boston Massachusetts.
Position: Associate Professor of Chemistry, University of California at Berkeley
How did you get your current job?
The usual way. I applied for faculty positions in 1995 in response to advertisements in C&E News
What do you think clinched the deal?
Good fortune and a strong publication record from my graduate and postdoctora...
Source: David Bradley Sciencebase - Songs, Snaps, Science - October 7, 2022 Category: Science Authors: David Bradley Tags: Chemistry Source Type: blogs
TLC Todd-versations: Todd Linsky in Conversation with Dr. Alan Greene
Todd Linsky, a food and organic industry veteran, hosts the podcast Todd-versations. He interviews guests from around the globe — influencers, leaders, and innovators in their respective fields. In this episode, Todd and Dr. Greene discuss the pediatric roots of longevity, the importance of nutrition in health, Dr. Greene’s reasons for creating DrGreene.com, his next projects, and a whole host of side topics.
Transcript of Todd-versation Podcast with Todd Linsky and Dr. Greene
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this conversation is brought to you in part by Calavo Growers the family of fresh!
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hey there everybody good ...
Source: Conversations with Dr Greene - October 6, 2022 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Source Type: blogs
