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How Could Digital Technology Make An Impact On Primary Care?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail how primary care should be carried out in the future! Digital health should become an organic part of primary care in the future I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions by optimising my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests....
Source: The Medical Futurist - September 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research Healthcare Innovation technology wearables GP primary care general practitioner Source Type: blogs

Microneedle Skin Patch Measures Cancer Biomarkers
Researchers at the Harvard Wyss Institute have developed a technique that lets clinicians to characterize and monitor melanoma. The system involves using a microneedle patch that can draw deep interstitial fluid into itself through a series of penetr...
Source: Medgadget - September 14, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Diagnostics Medicine Oncology harvard wyssinstitute Source Type: blogs

Biomaterial Injection Combines T Cell and Cancer Vaccine Treatments
Researchers at the Harvard Wyss Institute have developed an anti-cancer biomaterial treatment that combines adoptive T cell therapy and cancer vaccine technology to treat solid tumors. The researchers have called their technique SIVET, which is short...
Source: Medgadget - August 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Oncology harvard wyssinstitute Source Type: blogs

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species. We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The 2023 Skin-Checking Apps Landscape: Infographic
The most useful skin-checking applications allow users to take pictures of their suspicious skin lesions, upload these pictures to a server, the images are first evaluated by an AI algorithm and the results will be later validated by a dermatologist. We introduced several already, check here or here.  Earlier we called these apps an emerging trend, and still stand by this statement. If you are looking for a signature digital health solution, these are great examples, as they: address an existing demand rely on already existing infrastructure from the patients’ side (e.g.: their mobile phones) provide ea...
Source: The Medical Futurist - March 20, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Artificial Intelligence in Medicine Telemedicine & Smartphones future Healthcare technology skin checking digital health Source Type: blogs

Fight Aging! Newsletter, December 19th 2022
In conclusion, p16 deletion or p16 positive cell clearance could be a novel strategy preventing long term HFD-induced skin aging. Association of LDL-Cholesterol with Mortality https://www.fightaging.org/archives/2022/12/association-of-ldl-cholesterol-with-mortality/ Researchers here report on a study of LDL-cholesterol and mortality risk in older people. As they note, data on this topic is conflicted once one moves beyond the matter of cardiovascular disease. Over a lifetime, higher LDL-cholesterol makes it easier to reach the tipping point at which cholesterol deposited in blood vessel walls produces en...
Source: Fight Aging! - December 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

As Balwani and Holmes Head To Jail …Will Others in Health Tech Follow?
by MIKE MAGEE This week’s headlines seemingly closed a chapter on the story of medical research criminality in America. Ramesh “Sunny” Balwani, former president and COO of Theranos was sentenced to 13 years in prison for fraud. That’s 2 years more than his former business and romantic partner, Elizabeth Holmes. White crime criminal defense attorney for all things science tech, Michael Weinstein, took the opportunity to trumpet out a confident message that crime doesn’t pay in Medicine with these words, “It clearly sends a signal to Silicon Valley that puffery and fraud and misrepresentation will be pr...
Source: The Health Care Blog - December 9, 2022 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Ethics Henry K. Beecher Medical Ethics Mike Magee Theranos Source Type: blogs

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What Could You Do With Cheap Genome Sequencing Now?
Genome sequencing does definitely not equal fortune telling: it cannot predict how long you will live or what your body mass index will look like. However, it can tell you a lot about your sensitivity to drugs, your family history or whether you are a carrier of monogenic conditions. After the Human Genome Project was completed 20 years ago (for a whopping $2.7 billion), the dream was to be able to sequence a person’s genome for 1000 USD. After this became feasible, the next dream was to make it even cheaper: now it costs around 200 USD after Illumina’s innovation came to life. What is the next dream? To...
Source: The Medical Futurist - October 18, 2022 Category: Information Technology Authors: berci.mesko Tags: Genomics Personalized Medicine DNA dna testing Genetic testing genetics Genome Healthcare Innovation gc3 genome sequencing Source Type: blogs

Fight Aging! Newsletter, October 17th 2022
This study investigated whether multimorbidity is associated with incident dementia and whether associations vary by different clusters of disease and genetic risk for dementia. The study used data from the UK Biobank cohort, with baseline data collected between 2006 and 2010 and with up to 15 years of follow-up. Participants included women and men without dementia and aged at least 60 years at baseline. The presence of at least 2 long-term conditions from a preselected list of 42 conditions was used to define multimorbidity. A total of 206,960 participants (mean age 64.1 years) were included in the final sample, of...
Source: Fight Aging! - October 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

3 Reasons Why Patient Design Must Replace The Patient-Centricity Illusion
What is the difference between patient design and patient centricity? Why is the former a concept we need to embrace in the future of medicine, and why is it time to forget about the latter? These are the questions we examined in our latest paper published in the Journal of Medical Internet Research, authored by The Medical Futurist Dr Bertalan Mesko and patient scholar Dave deBronkart – widely known as ePatient Dave.  Patient centricity has been the buzzword of the past two decades, especially often used in the 2010s, from pharma companies to healthcare providers, it was loudly advertised everywhere. As nice...
Source: The Medical Futurist - September 27, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF E-Patients Future of Medicine Healthcare Design study patient empowerment patient design Digital Health Trend Study Future of healthcare patient centricity Source Type: blogs

Freeze Peach and Lies
We ' ve discussed here more than once the problematic aspects of the concept of free speech in general, and what the First Amendment means specifically.An excellent case in point is California Assembly Bill AB 2098. The link is to a post by physician David Gorski, who is  irredeemably long winded, bu the gist of it is:It shall constitute unprofessional conduct for a physician and surgeon to disseminate misinformation or disinformation related to COVID-19, including false or misleading information regarding the nature and risks of the virus, its prevention and treatment; and the development, safety, and effectiveness o...
Source: Stayin' Alive - September 26, 2022 Category: American Health Source Type: blogs

5 Scenarios Of How Your Health Data Can Be (Or Was Already) Stolen
I really don’t want to sound like Aunt Karen, suspecting a culprit hiding behind every bush, but chances are your health data was or will be stolen. This is a strong statement and might sound paranoid. But, as the old joke goes: being paranoid doesn’t mean someone is not after you.  Here we will introduce five general scenarios of how unknown third-party actors can access your health data without your knowledge (and consent). We introduce these to paint a clearer picture of how medical data can change hands and help you prepare to avoid it – as much as possible. You had a genetic test done You o...
Source: The Medical Futurist - September 15, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research Future of Food Healthcare Policy Security & Privacy Source Type: blogs

How An A.I.-Based Skin Checking App Can Work With A National Healthcare System
You might be already familiar with skin checking apps, we too have discussed them quite extensively recently. Skin checking applications allow users to take pictures of their suspicious skin lesions, upload these pictures to a server, the images are first evaluated by an A.I. algorithm and the results will be later validated by a dermatologist.  However, this time there is something new under the sun: AIP Labs and Semmelweis University (Hungary’s leading medical university) developed a skin checking application that offers several features we have not seen before. It was launched to work integrated with the natio...
Source: The Medical Futurist - September 8, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine Digital Health Research E-Patients Future of Medicine Healthcare Design Healthcare Policy Telemedicine & Smartphones AI dermatology skin skin cancer skin checker skin checking app digital Source Type: blogs