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Total 1329 results found since Jan 2013.
A 50-something with Regular Wide Complex Tachycardia: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith. Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
A 50-something with Regular Wide Complex Tachycardiaa: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith. Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Declining Cardiovascular Mortality in Atrial Fibrillation Patients
A downward trend in cardiovascular mortality has prevailed for some time now, and we might take the data here as an example of ways in which improved options for detection and treatment produce results in specific portions of the patient population. Also worthy of note is the point that these older patients have many issues, and while slowing the pace of cardiovascular decline with age should have beneficial effects throughout the body, reduced cardiovascular mortality due to improved treatment that specifically focuses on cardiovascular disease allows other age-related conditions to claim a greater proportion of the popul...
Source: Fight Aging! - September 1, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
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Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants in...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Longevity-Associated Variant of BPIFB4 Reduces Heart Disease Severity
Few human longevity-associated gene variants are replicated in multiple patient populations. One of those is a variant of BPIFB4, that appears to improve immune function and lower inflammation by adjusting the behavior of macrophage cells of the innate immune system. Delivering the variant to mice using a gene therapy has similar effects. It may well operate via other mechanisms as well, however. Few proteins in a living cell turn out to have only one purpose.
In today's open access paper, researchers report that the BPIFB4 variant reduces the severity of coronary artery disease in humans and mice. Delivering the va...
Source: Fight Aging! - August 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
THCB 20th Birthday Classic: As I’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT
Our 20th birthday continues with a few classics coming out. Back in 2005 I was really cutting a lyrical rug, and would never miss a chance to get that Cambridge training in Marxism into use. This essay about whether health care should be a public or private good has always been one of my favorites, even if I’m not sure Starbucks is still making Frappuccinos. And 18 years later the basic point of this essay remains true, even if many of you will not have a clue who Vioxx or Haliburton were or why they mattered back then!
Those of you who think I’m an unreconstructed commie will correctly suspec...
Source: The Health Care Blog - August 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Communism Frappuccinos Source Type: blogs
Survivors of Nuclear Weapon Use in Early Life Exhibit Accelerated Immune Aging in Late Life
It probably strains the meaning of the term to call the aftermath of the use of nuclear weapons at the end of the Second World War a natural experiment, but nonetheless there has been considerable study of survivors from those events and their health relative to control populations in other parts of Japan. Irradiation is known to produce what is effectively accelerated aging in the context of cancer treatment, producing an increased burden of senescent cells that then ensure the later course of health for survivors is worse than would otherwise be the case, absent both cancer and treatment. In the case of exposure to radia...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
How Cuff Size Impacts Blood Pressure Measurement Accuracy – The Study
Conclusion
The journey through the nuances of blood pressure measurements unveils a pivotal lesson: individuality matters. The convenience of a one-size-fits-all approach, while appealing, may not stand up to the rigorous demands of health accuracy.
Each person’s uniqueness, from their arm size to their health conditions, necessitates a tailored approach, especially when it comes to something as vital as blood pressure readings.
Yet, the responsibility doesn’t just lie with the medical professionals. As readers, as individuals, there’s a clarion call for proactivity. Being informed, asking quest...
Source: The EMT Spot - August 10, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Isometric Exercises: A New Hope For Hypertension Management
Conclusion
As we reflect on the power of exercise in managing hypertension, it’s clear that isometric workouts stand as a compelling addition to the traditional regimen.
Their role in significantly reducing both systolic and diastolic blood pressure, as the study suggests, offers fresh hope for individuals navigating the challenges of high blood pressure.
Yet, as we embrace these workouts, it’s essential to remember the words of healthcare professionals like Joanne Whitmore and Jim Pate. Exercise, though pivotal, is just one aspect of a broader strategy to manage hypertension.
Alongside this, life...
Source: The EMT Spot - July 31, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Central Agonists For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
In summary, central agonists, a notable class of hypertension medications, offer an alternative modality when other first-line antihypertensive treatments fail to show desired results or cause intolerable side effects.
They operate via a unique neurocentric mechanism that primarily functions centrally in the brain, impacting blood pressure regulation by decreasing systemic arterial pressure and heart rate.
Despite their potential side effects and potential for interactions with other drugs, their therapeutic utility in the context of hypertension management remains undiminished.
Moreover, certain cen...
Source: The EMT Spot - July 27, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Handling Heat On Blood Pressure Medication: Your Summer Health Guide
Conclusion
Summing it up, individuals taking blood pressure medication must be cautious during the hot weather season. Heat exposure can significantly impact blood pressure and may amplify the effects of medication, leading to potentially harmful health conditions.
These risks, however, can be managed with the right precautions such as staying hydrated, dressing appropriately, and planning outdoor activities during cooler times of the day.
Importantly, each person’s response to heat and medication varies. Hence, a one-size-fits-all approach isn’t ideal. Your healthcare provider is an invaluable resourc...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
A Study Reveals The Impact Of Childhood TV Habits On Adult Blood Pressure
Conclusion
In sum, monitoring and managing screen time is not just about today’s habits but a long-term investment in a child’s future health, particularly their blood pressure levels. The data linking childhood TV viewing to adult health problems like high blood pressure underscores the urgency of this matter.
However, understanding is just the first step. From here, we must translate this knowledge into action – through parental control, societal initiatives, healthier dietary habits, and increased physical activity. But we must also remember that screen time isn’t all bad – the conten...
Source: The EMT Spot - July 25, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
