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Total 1510 results found since Jan 2013.

Medical Control of Hypertension Largely Removes Increased Risk of Dementia
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
Source: Fight Aging! - September 20, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mitochondrial Epigenetics in Age-Related Mitochondrial Dysfunction
The hundreds of mitochondria present in every cell in the body undertake the essential duty of producing chemical energy store molecules, adenosine triphosphate (ATP), used to power the cell. With age, mitochondria become less efficient and more damaged, generating oxidative stress and triggering inflammation while producing less ATP than is optimal. This is thought to be a major contribution to degenerative aging, though as for all contributions to aging, it requires a highly targeted way to improve mitochondrial function in order to determine just how important it is. That highly targeted therapy doesn't yet exist in a u...
Source: Fight Aging! - September 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Judge for yourself the management of this patient with " NSTEMI, multivessel disease "
DISCUSSION:The administration of opioid analgesia prior to cath in patients with concern for ACS is associated with longer door-to-balloon times, and greater peak troponin levels. The rate of Occlusion MI in those who received pre-cath opioids was double the rate of those without pre-cath opioids, and STEMI(-) OMI patients who received pre-cath opioids waited 10 hours on average longer to get cath than those who did not received opioids. These results add support to our hypothesis that a major mechanism of harm caused by opioid medications in ACS patients involves delays to the cath lab for patients with STEMI(-) OMI.=====...
Source: Dr. Smith's ECG Blog - September 10, 2023 Category: Cardiology Authors: Pendell Source Type: blogs

Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men. « Back to Top Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/ Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A 50-something with chest pain.
This was sent by anonymous The patient is a 55-year-old male who presented to the emergency department after approximately 3 to 4 days of intermittent central boring chest pain initially responsive to nitroglycerin, but is now more constant and not responsive to nitroglycerin. It is unknown when this pain recurred and became constant.More past history: hypertension, tobacco use, coronary artery disease with two vessel PCI to the right coronary artery and circumflex artery several years prior.  He reports feeling nauseated with emesis. He reports that this chest pain feels different than prior chest...
Source: Dr. Smith's ECG Blog - September 3, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

How Cuff Size Impacts Blood Pressure Measurement Accuracy – The Study
Conclusion The journey through the nuances of blood pressure measurements unveils a pivotal lesson: individuality matters. The convenience of a one-size-fits-all approach, while appealing, may not stand up to the rigorous demands of health accuracy. Each person’s uniqueness, from their arm size to their health conditions, necessitates a tailored approach, especially when it comes to something as vital as blood pressure readings. Yet, the responsibility doesn’t just lie with the medical professionals. As readers, as individuals, there’s a clarion call for proactivity. Being informed, asking quest...
Source: The EMT Spot - August 10, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Elderly, Constipation, And Hypertension: Unraveling The Surprising Connection From A Recent Study
Conclusion As we’ve delved into the intricate web linking constipation and hypertension, one thing becomes crystal clear: the world of medicine is vast, and understanding even commonplace issues like constipation can unlock deeper insights into more pressing concerns like cardiovascular diseases. This La Trobe University study shines a spotlight on the urgency of recognizing and effectively addressing non-traditional risk factors. For our readers, especially those gracefully journeying into their 60s and beyond, let this be a gentle nudge. Your health is a mosaic of interconnected pieces. Something as seemingly...
Source: The EMT Spot - August 6, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Isometric Exercises: A New Hope For Hypertension Management
Conclusion As we reflect on the power of exercise in managing hypertension, it’s clear that isometric workouts stand as a compelling addition to the traditional regimen. Their role in significantly reducing both systolic and diastolic blood pressure, as the study suggests, offers fresh hope for individuals navigating the challenges of high blood pressure. Yet, as we embrace these workouts, it’s essential to remember the words of healthcare professionals like Joanne Whitmore and Jim Pate. Exercise, though pivotal, is just one aspect of a broader strategy to manage hypertension. Alongside this, life...
Source: The EMT Spot - July 31, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Central Agonists For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In summary, central agonists, a notable class of hypertension medications, offer an alternative modality when other first-line antihypertensive treatments fail to show desired results or cause intolerable side effects. They operate via a unique neurocentric mechanism that primarily functions centrally in the brain, impacting blood pressure regulation by decreasing systemic arterial pressure and heart rate. Despite their potential side effects and potential for interactions with other drugs, their therapeutic utility in the context of hypertension management remains undiminished. Moreover, certain cen...
Source: The EMT Spot - July 27, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Handling Heat On Blood Pressure Medication: Your Summer Health Guide
Conclusion Summing it up, individuals taking blood pressure medication must be cautious during the hot weather season. Heat exposure can significantly impact blood pressure and may amplify the effects of medication, leading to potentially harmful health conditions. These risks, however, can be managed with the right precautions such as staying hydrated, dressing appropriately, and planning outdoor activities during cooler times of the day. Importantly, each person’s response to heat and medication varies. Hence, a one-size-fits-all approach isn’t ideal. Your healthcare provider is an invaluable resourc...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Potassium: The Silent Ally In Your Battle With Hypertension
Conclusion: Balancing Potassium Intake As Part Of An Overall Healthy Lifestyle While elevating your potassium intake can be instrumental in your battle against high blood pressure, it’s essential to remember that it’s part of a broader health strategy. There’s no magic bullet in managing blood pressure. A symphony of lifestyle adjustments working in harmony is what lays the groundwork for victory. Eating an overall healthy diet, limiting your sodium intake, getting regular exercise, and quitting smoking if needed – all these factors dance hand in hand with your potassium intake. These habits f...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

A Study Reveals The Impact Of Childhood TV Habits On Adult Blood Pressure
Conclusion In sum, monitoring and managing screen time is not just about today’s habits but a long-term investment in a child’s future health, particularly their blood pressure levels. The data linking childhood TV viewing to adult health problems like high blood pressure underscores the urgency of this matter. However, understanding is just the first step. From here, we must translate this knowledge into action – through parental control, societal initiatives, healthier dietary habits, and increased physical activity. But we must also remember that screen time isn’t all bad – the conten...
Source: The EMT Spot - July 25, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Zilebesiran: A Promising Leap Forward In Hypertension Management
Conclusion As we draw the curtain on this insightful dive into Zilebesiran, a couple of takeaways stand out. Zilebesiran, the promising twice-yearly shot, is opening new frontiers in hypertension management. With its ability to suppress angiotensin production, it offers a fresh approach that could alleviate the burden of daily pill regimens. But the shot is still in its developmental phase, and further research is crucial to fully understand its capabilities and limitations. Still, it’s important to remember that medications are only a part of the solution. The enduring message from health professionals is ...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs