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Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Above Elbow Amputee Controls Individual Bionic Fingers
Researchers at Chalmers University of Technology in Sweden have developed a new technique that could allow above-elbow amputees to better use robotic prostheses, including making individual finger movements. Unlike below-elbow amputees, these patient...
Source: Medgadget - August 4, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Rehab chalmersuniv Source Type: blogs

Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells. Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Can You Receive A Massage With Hypertension?
Conclusion To circle back to our original question: Can you receive a massage if you have hypertension? The current body of evidence suggests that it’s possible, but it must be done responsibly and under professional supervision. Remember, while techniques like massage can play a role in managing hypertension, they form part of a larger management plan. This should encompass regular health checkups, appropriate medication (if prescribed), dietary modifications, and overall lifestyle adaptations. Read also: Can You Practice Yoga With Hypertension? Reference The Effects of Swedish Massage on Blood ...
Source: The EMT Spot - June 17, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Using Robots and Artificial Intelligence to Search for New Medicines
Courtesy of Dr. Adam Gormley. Adam Gormley, Ph.D., describes himself as a creative and adventurous person—albeit, not creative in the traditional sense. “Science allows me to be creative; to me, it’s a form of art. I love being outdoors, going on sailing trips, and spending time adventuring with my family. Research is the same—it’s an adventure. My creative and adventurous sides have combined into a real love for science,” he says. Dr. Gormley currently channels his passion for science into his position as an assistant professor of biomedical engineering at Rutgers University in Piscataway, New Jersey. Lea...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 24, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Medicines Profiles Source Type: blogs

Wound Dressing Detects Infection, Changes Color
Researchers at Linköping University in Sweden created a wound dressing that can provide a visual indication if the underlying wound is infected. Chronic wounds are difficult to manage, and presently healthcare staff must remove the dressing regularl...
Source: Medgadget - May 1, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Materials Military Medicine Surgery liu_universitet Source Type: blogs

Stimulating Wounds with Electricity for Rapid Healing
Researchers at Chalmers University of Technology in Sweden have developed a microfluidic system to test the effects of electrical stimulation in wound healing. The researchers hope that their experiments might lead to new medical devices that can ass...
Source: Medgadget - April 25, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Surgery Source Type: blogs

Fight Aging! Newsletter, March 13th 2023
In this study, we report the extensive and progressive accumulation of misfolded proteins during natural aging/senescence in different models, in the absence of disease. We coined the term age-ggregates to refer to this subset of proteins. Our findings demonstrate that age-ggregates exhibit the main characteristics of misfolded protein aggregates implicated in PMDs, including insolubility in detergents, protease-resistance, and staining with dyes specific for misfolded aggregates. Misfolded protein aggregates with these characteristics are thought to be implicated in some of today most prevalent diseases, including Alzheim...
Source: Fight Aging! - March 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A COVID-19 vaccine exemption letter
BY ANISH KOKA I recently saw a young man who came to see me because his place of future employment, a large health system was requiring him to complete the 1º series of his COVID-19 vaccination. He was concerned because he had chest pain after his first mRNA vaccine and was uncomfortable with the risks of a second mRNA dose. He attempted to get a Johnson and Johnson vaccine and was told by pharmacists he was not allowed to mix and match this particular vaccine as he had already received an mRNA dose. With no other option, he came to ask me whether I thought a vaccine exemption was reasonable in his case. He already had...
Source: The Health Care Blog - February 24, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Anish Koka COVID-19 vaccine exemption vaccines Source Type: blogs

Antibacterial Peptide Spray Safe for Use on Wounds
Researchers at Chalmers University of Technology in Sweden have developed an antimicrobial spray that is safe to use on wounds and in the body, including as an antimicrobial coating on implantable or in-dwelling devices, such as urinary catheters. Th...
Source: Medgadget - February 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Surgery antibiotic resistance chalmersuniv Source Type: blogs

Flexible Sensors Detect Heavy Metals in Sweat
Researchers at the University of São Paulo in Brazil, along with collaborators in Germany and Sweden, have developed a flexible sensor that can detect heavy metals in sweat, an easily obtainable bodily fluid. Heavy metals, such as lead or cadmium, c...
Source: Medgadget - January 31, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Source Type: blogs

The Chemistry Clicked: Two NIGMS-Funded Researchers Receive Nobel Prize
Since its creation in 1962, NIGMS has supported the work of the recipients of 94 Nobel Prizes—44 in physiology or medicine and 50 in chemistry. NIGMS-funded investigators perform cutting-edge basic research that is foundational to understanding normal life processes and disease. Such important breakthroughs in chemistry and biology often fuel more focused research that, years later, leads to important medical advances or products such as medicines or biotechnology tools. Credit: Niklas Elmehed. The most recent NIGMS-supported Nobel laureates are Carolyn R. Bertozzi, Ph.D., the Anne T. and Robert M. Bass Professor in...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 7, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Cool Tools/Techniques Nobel Prize Profiles Source Type: blogs

The Top 10 Digital Health Stories Of 2022
Edging towards the end of the year, it is time for a summary of how digital health progressed in 2022. It is easy to get lost in the noise – I myself shared well over a thousand articles, studies and news items between January and the end of November 2022. Thus, just like in 2021, 2020 (and so on), I picked the 10 topics I believe will have the most significance in the future of healthcare. 1. The Rise Of Digital Therapeutics (DTx) Unlike a number of unsubstantial hypes (NFTs, Metaverse to name a few), we see DTx as a meaningful trend that has the capacity to bring major short-term improvements in personalised ...
Source: The Medical Futurist - November 29, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF digital health pharma drones digital health trends vocal biomarkers WHO DTx digital therapeutics Metaverse virtual ward summary AI healthcare worker Source Type: blogs