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Great Food Can Improve Brain Development (Even Before Birth)
What we eat – and what our kids eat – affects so much in life: appearance, energy, cognition, focus, mood, how often we get sick, how quickly we get better, how likely we are to develop a chronic disease, and how we age.
Every bite of food is either an investment in our future, a new debt we are taking out, or some of both.
There are many ways to enjoy the benefits of real food. One healthy way of eating that has been studied a lot is the Mediterranean diet, a diet rich in fruits, vegetables, whole grains, beans, nuts, seeds, fish, herbs, spices, and olive oil. Red meats, processed foods, and added sugars are limited.
...
Source: Conversations with Dr Greene - September 5, 2023 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Uncategorized Mediterranean Diet Pregnancy Nutrition Top Family Nutrition Source Type: blogs
Potassium: The Silent Ally In Your Battle With Hypertension
Conclusion: Balancing Potassium Intake As Part Of An Overall Healthy Lifestyle
While elevating your potassium intake can be instrumental in your battle against high blood pressure, it’s essential to remember that it’s part of a broader health strategy. There’s no magic bullet in managing blood pressure. A symphony of lifestyle adjustments working in harmony is what lays the groundwork for victory.
Eating an overall healthy diet, limiting your sodium intake, getting regular exercise, and quitting smoking if needed – all these factors dance hand in hand with your potassium intake. These habits f...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells.
Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn
A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect
How to Construct Measures of Biological Age
A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls
In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals
Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome
Intestinal Barrier Dysfunction as a Feature of Aging in Many Species
NAFLD as an Age-Related Condition
Towards Sensory Hair Cell Regeneration in the Inner Ear
Raised Levels of PLG...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved.
Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 17th 2023
In conclusion, oral NR altered the gut microbiota in rats and mice, but not in humans. In addition, NR attenuated body fat mass gain in rats, and increased fat and energy absorption in the HFD context.
Glycine Supplementation as a Methionine Restriction Mimetic
https://www.fightaging.org/archives/2023/04/glycine-supplementation-as-a-methionine-restriction-mimetic/
Supplementation with the non-essential amino acid glycine has been shown to modestly slow aging in short-lived laboratory species. In today's open access review paper, researchers note glycine supplementation as essentially a calorie restrictio...
Source: Fight Aging! - April 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
poem
Au SableThe summer before residency started in ChicagoI went north to Grayling, Michigan with a backpackAnd the last of a dreamy eyed sociopathic certaintyTo spend a weekend fly fishing on the edgesOf the swift black flat Au Sable river.I thought I had it all won,I ’d played some cards wellParlayed a little luck into a tidy stack That bought me access to higher stakes tables. I was ready to roll the dice and gamble.But first, before sitting down with the high rollersIt was off to the swift black Au Sable river In the summer before the illusions fractured,Before I realized everything I hadBarely cover...
Source: Buckeye Surgeon - April 16, 2023 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs
Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Secret Ways Healthcare AI Companies Might Use Your Personal Data
Pictures, text prompts, documents and health metrics are just a few examples of data we’re giving away to different AI applications and thus, to different companies/organizations. While it’s always good to know what happens to your data, it is especially relevant in healthcare settings and regarding health data.
The rise of social media platforms signifies the beginning of a new era, one where individuals become valuable resources: providing tons of personal data that can be utilised for commercial purposes. But as the plethora of AI applications begins to enter our lives, we have to level up our games and become mu...
Source: The Medical Futurist - February 21, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Artificial Intelligence in Medicine AI data privacy digital health data digital health privacy Source Type: blogs
Here Is What Even Healthcare AI Companies Do With Your Data
Pictures, text prompts, documents and health metrics are just a few examples of data we’re giving away to different AI applications and thus, to different companies/organizations. While it’s always good to know what happens to your data, it is especially relevant in healthcare settings and regarding health data.
The rise of social media platforms signifies the beginning of a new era, one where individuals become valuable resources: providing tons of personal data that can be utilised for commercial purposes. But as the plethora of AI applications begins to enter our lives, we have to level up our games and become mu...
Source: The Medical Futurist - February 21, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Artificial Intelligence in Medicine digital health privacy AI data privacy digital health data Source Type: blogs
Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes.
Communication Between Blood and Brain in Aging and Rejuvenation
https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/
As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inter...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Investigating the Comparative Biology of Variations in Rockfish Species Life Spans
The comparative biology of aging, the study of aging in species with widely divergent life spans, is hoped to improve the catalog and understanding of important mechanisms of aging. It may or may not turn out to be the case that the biochemistry of long-lived species can give rise to practical therapies that slow aspects of human aging, at least in the near future of the next few decades. Engineering a human that ages more slowly seems a far more daunting task than the production of rejuvenation therapies that repair the known forms of cell and tissue damage that drive aging.
An alternative to comparing other specie...
Source: Fight Aging! - January 26, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, December 26th 2022
This article on senolytic therapies to selectively remove senescent cells in old tissues is in part a matter of Unity Biotechnology talking up their position. The company suffered from first mover disadvantage in bringing senolytic drugs into clinical development. The field has made progress very rapidly over the last decade, and startups founded even just a couple of years after Unity's launch benefited from greater knowledge and a selection of better technologies to work with. Still, one can be talking up one's position and also be right. The accumulation of senescent cells is profoundly harmful, a significant contributi...
Source: Fight Aging! - December 25, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Medical Student Perspective on Loss and Self-Awareness
“There are these two young fish swimming along and they meet an older fish swimming the other way, who nods at them and says, ‘Morning, boys. How’s the water?’ And the two young fish swim on for a bit, and eventually one of them looks at the other and goes, ‘What is water?”– David Foster Wallace, Kenyon College Commencement 2005, “This is Water.”
The journey from medical school to residency goes fast: there scarcely seems time enough to do it all. Although we practice again and again so we can better discern what troubles our patients, we do not do the same for ourselves. In fact, unti...
Source: Academic Medicine Blog - December 6, 2022 Category: Universities & Medical Training Authors: Laura Siegel Tags: Mental Health Self Care wellness Source Type: blogs
Fight Aging! Newsletter, October 17th 2022
This study investigated whether multimorbidity is associated with incident dementia and whether associations vary by different clusters of disease and genetic risk for dementia. The study used data from the UK Biobank cohort, with baseline data collected between 2006 and 2010 and with up to 15 years of follow-up. Participants included women and men without dementia and aged at least 60 years at baseline. The presence of at least 2 long-term conditions from a preselected list of 42 conditions was used to define multimorbidity.
A total of 206,960 participants (mean age 64.1 years) were included in the final sample, of...
Source: Fight Aging! - October 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
