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Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men. « Back to Top Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/ Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants in...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Elderly, Constipation, And Hypertension: Unraveling The Surprising Connection From A Recent Study
Conclusion As we’ve delved into the intricate web linking constipation and hypertension, one thing becomes crystal clear: the world of medicine is vast, and understanding even commonplace issues like constipation can unlock deeper insights into more pressing concerns like cardiovascular diseases. This La Trobe University study shines a spotlight on the urgency of recognizing and effectively addressing non-traditional risk factors. For our readers, especially those gracefully journeying into their 60s and beyond, let this be a gentle nudge. Your health is a mosaic of interconnected pieces. Something as seemingly...
Source: The EMT Spot - August 6, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Isometric Exercises: A New Hope For Hypertension Management
Conclusion As we reflect on the power of exercise in managing hypertension, it’s clear that isometric workouts stand as a compelling addition to the traditional regimen. Their role in significantly reducing both systolic and diastolic blood pressure, as the study suggests, offers fresh hope for individuals navigating the challenges of high blood pressure. Yet, as we embrace these workouts, it’s essential to remember the words of healthcare professionals like Joanne Whitmore and Jim Pate. Exercise, though pivotal, is just one aspect of a broader strategy to manage hypertension. Alongside this, life...
Source: The EMT Spot - July 31, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Handling Heat On Blood Pressure Medication: Your Summer Health Guide
Conclusion Summing it up, individuals taking blood pressure medication must be cautious during the hot weather season. Heat exposure can significantly impact blood pressure and may amplify the effects of medication, leading to potentially harmful health conditions. These risks, however, can be managed with the right precautions such as staying hydrated, dressing appropriately, and planning outdoor activities during cooler times of the day. Importantly, each person’s response to heat and medication varies. Hence, a one-size-fits-all approach isn’t ideal. Your healthcare provider is an invaluable resourc...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Potassium: The Silent Ally In Your Battle With Hypertension
Conclusion: Balancing Potassium Intake As Part Of An Overall Healthy Lifestyle While elevating your potassium intake can be instrumental in your battle against high blood pressure, it’s essential to remember that it’s part of a broader health strategy. There’s no magic bullet in managing blood pressure. A symphony of lifestyle adjustments working in harmony is what lays the groundwork for victory. Eating an overall healthy diet, limiting your sodium intake, getting regular exercise, and quitting smoking if needed – all these factors dance hand in hand with your potassium intake. These habits f...
Source: The EMT Spot - July 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

A Study Reveals The Impact Of Childhood TV Habits On Adult Blood Pressure
Conclusion In sum, monitoring and managing screen time is not just about today’s habits but a long-term investment in a child’s future health, particularly their blood pressure levels. The data linking childhood TV viewing to adult health problems like high blood pressure underscores the urgency of this matter. However, understanding is just the first step. From here, we must translate this knowledge into action – through parental control, societal initiatives, healthier dietary habits, and increased physical activity. But we must also remember that screen time isn’t all bad – the conten...
Source: The EMT Spot - July 25, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Zilebesiran: A Promising Leap Forward In Hypertension Management
Conclusion As we draw the curtain on this insightful dive into Zilebesiran, a couple of takeaways stand out. Zilebesiran, the promising twice-yearly shot, is opening new frontiers in hypertension management. With its ability to suppress angiotensin production, it offers a fresh approach that could alleviate the burden of daily pill regimens. But the shot is still in its developmental phase, and further research is crucial to fully understand its capabilities and limitations. Still, it’s important to remember that medications are only a part of the solution. The enduring message from health professionals is ...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Pulmonary Arterial Hypertension: Unraveling Its Impact On Heart And Lungs
Conclusion Navigating the complexities of Pulmonary Arterial Hypertension (PAH) might seem daunting. However, with the right knowledge and proactive approach, it’s possible to manage the condition and maintain a good quality of life. PAH, a unique type of high blood pressure affecting the arteries in the lungs, can put extra strain on the heart. Over time, this can lead to heart failure. The condition’s root cause may vary, from genetic factors to other health issues like heart defects, liver disease, or autoimmune diseases. Remember, sometimes the cause remains unknown, resulting in idiopathic pulmonary ...
Source: The EMT Spot - July 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Primary Hypertension: The Unseen Risk For Healthy People
Conclusion In conclusion, even the healthiest individuals can develop primary hypertension, a condition that affects a significant portion of the U.S. adult population. With its roots often hidden in our genetic makeup and influenced by various lifestyle factors, hypertension can quietly disrupt our wellbeing, earning its nickname as the “silent killer.” Real-life experiences, such as Martin Cassels’, highlight that maintaining an active, healthy lifestyle doesn’t render one immune to this condition. However, it underscores the importance of regular health check-ups and the value of a second o...
Source: The EMT Spot - July 13, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

In Other Words: What ’s It Mean to Be Organic?
The word organic is often used to talk about fruits and vegetables that have been produced in a specific way, typically without the use of synthetic fertilizers and pesticides. But to chemists, organic refers to carbon-containing compounds that are the basis for all living organisms. Ironically, the chemicals prohibited in the farming of organic produce are usually organic molecules. Credit: NIGMS. Organic chemists study, create, and explore carbon-containing molecules. Most organic molecules contain carbon and hydrogen, but they can also include other elements like nitrogen, oxygen, phosphorus, and more. Organic comp...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - July 12, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology In Other Words Source Type: blogs

The Best ChatGPT Plugins: How To Add Browsing, Learning, Wolfram And More
ChatGPT plugins became available a few weeks ago and I have been testing them to see what they can do. They offer interesting new features from all walks of life, so let’s take a look at these new gadgets. What are ChatGPT plugins and how you can get them?  You can imagine these as apps on your phone: little extra programs that give ChatGPT extra skills.  How to enter the beta features?  You need to have GPT-4 access, which comes with the paid accounts. If you have GPT-4, click on your name on the bottom left, go to settings, click on beta features and allow them with the slider.  How t...
Source: The Medical Futurist - June 27, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF artificial intelligence ChatGPT plugins digital health Medicine AI in healthcare AI in medicine Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Age-Related Dysfunction of Water Homeostasis
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechanisms involved in the vulnerability of old people to harmful levels of dehydration. Ageing is accompanied by an increased prevalence of disorders of body salt and water composition. As revealed by the UK Dehydration Recognition In Our Elders (DRIE), 20% of residents in ...
Source: Fight Aging! - June 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred year...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs