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Total 132 results found since Jan 2013.

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Is More Physician-Owned Hospitals the Solution to our Health Cost problem?
BY JEFF GOLDSMITH Robert Frost once said,  “Home is where, when you have to go there, they have to take you in.” Increasingly, in our struggling society, that place is your local full service community hospital.  During COVID, if it wasn’t your local hospital standing up testing sites, pumping out vaccinations and working double overtime helping patients breathe, we would have lost several hundred thousand more of our fellow Americans.   But it wasn’t just COVID where hospitals leaped into the breach.    As primary care physicians’ practices collapsed from documentation overburde...
Source: The Health Care Blog - July 26, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: The Business of Health Care Affordable Care Act COVID Jeff Goldsmith Physician-Owned hospitals Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, July 10th 2023
In conclusion, the examination of the GBA can aid in understanding the etiology and development of NDs, which may benefit the improvement of clinical treatments for these disorders and ND interventions. This review indicates existing knowledge about the involvement of microbiota present in the gut in NDs and potential treatment options. The Aging of the Enteric Nervous System https://www.fightaging.org/archives/2023/07/the-aging-of-the-enteric-nervous-system/ The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome a...
Source: Fight Aging! - July 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lab-Created Mini Lungs to Study Respiratory Infections
Researchers at Rockefeller University have developed a cell culture platform in which to grow ‘lung buds’ from human embryonic stem cells. The tiny structures are similar to the lung buds that form during fetal development, and they contain tiny ...
Source: Medgadget - June 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Pathology Public Health RockefellerUniv Source Type: blogs

Ask and Tell: Family Caregiving as a Social Determinant of Health
I sat in front of my doctor for the first time since before the pandemic. She was concerned: “You’re way overdue for a couple of screening tests and a vaccination.” I explained that between Covid waves and caregiving for my mom, I’d had to cancel and reschedule the most the screening test at least 3 times. And, caregiving for my mom was becoming more intense, which was going to create more challenges. She asked if anyone was helping me. I explained that my husband is a huge help. But I’m the only adult child who lives within driving distance. And just within the past few months there’s been a couple of falls, a...
Source: EMR and HIPAA - June 14, 2023 Category: Information Technology Authors: Geri Lynn Baumblatt Tags: Clinical Communication and Patient Experience Healthcare IT Hospital - Health System care partner family caregiver patient clinician relationship patient engagement SDOH Social Determinants of Health Source Type: blogs

Air, Air, Everywhere, and Not a Breath Safe to Take
BY KIM BELLARD If you live, as I do, anywhere in the Eastern half of the country, for the past week you’ve probably been thinking about something you’re not used to: wildfires.  Sure, we’ve all been aware of how wildfires routinely plague the West Coast, particularly Oregon and Washington, but it’s novel for the East. So when the smoke from Canadian wildfires deluged cities through the East and Midwest, it came as kind of a shock. For a day last week, New York City supposedly had the worst air quality in the world.  The next day Philadelphia had that dubious distinction.  The air quality index ...
Source: The Health Care Blog - June 14, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Non-Health Climate Change East Coast Kim Bellard West Coast Wildfires Source Type: blogs

Better Health Care Tests, Faster
This article looks at some specific problems and solutions. Speeding up Test Development We’ve seen with COVID-19 how quickly a virus can evolve and how hard it is to design both tests and vaccinations that accommodate different variants. Virax Biolabs uses data from the World Health Organization and others to develop tests quickly. For instance, new viral variants tend to spread in the southern hemisphere before hitting the northern hemisphere in our Winter, so Virax can check existing data to prepare better tests for the North. The company is developing a T-cell diagnostics and profiling platform called Virax Immu...
Source: EMR and HIPAA - June 13, 2023 Category: Information Technology Authors: Andy Oram Tags: Health IT Company Healthcare IT Hospital - Health System Interoperability CLIA COVID-19 Hydreight Immunexpress ixlayer Laboratories Labs Rolland Carlson Sepsis Sepsis Lab Tests Septicyte Shane Madden testing Tomasz George Source Type: blogs

Mobile Printer Produces Microneedle Vaccines
Researchers at MIT have developed a printer that can create large numbers of microneedle patch-style vaccines in places where they are needed quickly. Moreover, the printed patches can deliver thermostable mRNA vaccines, whereby the mRNA therapeutic ...
Source: Medgadget - May 3, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health microneedle mit Source Type: blogs

Fight Aging! Newsletter, May 1st 2023
In conclusion, frailty progression accelerates in males with one LTCs and females with two LTCs or more. Health providers should be aware of planning a suitable intervention once the elderly have two or more health conditions. Plasma Transfer Lowers Epigenetic Age and Mortality in Rats https://www.fightaging.org/archives/2023/04/plasma-transfer-lowers-epigenetic-age-and-mortality-in-rats/ Plasma transfer from young to old individuals has produced mixed results in animals and little to no benefit in humans where assessed rigorously. These studies were driven by the hypothesis that young plasma contains me...
Source: Fight Aging! - April 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Maximizing Healthcare Data Starts with a Human-Centric Approach
The following is a guest article by Chris Anello, Director of Digital Platforms at iTech AG The COVID-19 pandemic pushed healthcare organizations to the edge and exposed both challenges and opportunities related to public health data. Some of these opportunities come down to basics of data interoperability and data sharing—challenges highlighted in a GAO report published last fall. But when it comes to putting the data in front of citizens, healthcare decision makers, government employees, and other key stakeholders, customer experience becomes a major part of the equation. The appetite for data around COVID-19 cases, ho...
Source: EMR and HIPAA - April 28, 2023 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data C-Suite Leadership Communication and Patient Experience Health IT Company Healthcare IT CDC Chris Anello COVID-19 CX Data Interoperability Data Sets Data Sharing GAO Healthcare Accessibility Healthcare Data Source Type: blogs

Nanoparticles Deliver mRNA Therapy to the Lungs
Researchers at MIT have developed lipid nanoparticles that are highly efficient at delivering mRNA therapies to lung cells. Getting therapeutic agents into the lungs can be challenging, but there are a variety of medical challenges that could be addr...
Source: Medgadget - April 18, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Nanomedicine News mit Source Type: blogs

Tiny Cylinders for Controlled Drug Release
Researchers at Rice University have developed a new type of microparticle for drug delivery, made from a polymer called PLGA that has already been extensively explored as a component in drug delivery systems. However, what makes these new particles d...
Source: Medgadget - April 10, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine riceuniversity Source Type: blogs

CRISPR Combined with Glowing Proteins for Viral Detection
Researchers at Eindhoven University of Technology in the Netherlands have developed a sensitive diagnostic test for viral pathogens that is suitable for use in low-resource regions. The test is based on CRISPR proteins that can detect viral genetic m...
Source: Medgadget - March 23, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Genetics Medicine Public Health CRISPR TUeindhoven Source Type: blogs