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mRNA Immunotherapy Targets Cancer
Researchers at the Mount Sinai Hospital have developed an mRNA-based treatment for cancer. The approach combines the delivery of mRNA therapy in lipid nanoparticles and also involves co-delivering dendritic cells that have also been primed through tr...
Source: Medgadget - August 25, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Oncology immunotherapy MountSinaiNYC mRNA Immunotherapy Source Type: blogs

20th Birthday Classic: “Healthcare” vs. “Health Care”: The Definitive Word(s)
This is the last of the classics that THCB will run to celebrate our 20th birthday. And we are finally tackling the most important of questions. Is what we call this thing one word or two? Back in 2012 Michael Millenson had the definitive answer–Matthew Holt By MICHAEL L. MILLENSON A recent contributor to this blog wondered about the correctness of “health care” versus “healthcare.” I’d like to answer that question by channeling my inner William Safire (the late, great New York Times language maven). If you’ll stick with me, I’ll also disclose why the Centers for Medicare & Medicaid Serv...
Source: The Health Care Blog - August 25, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy health care Healthcare Michael Millenson Source Type: blogs

Gene Therapy Targets Chronic Pain
Scientists at New York University have developed a gene therapy for chronic pain. The technology works by targeting the NaV1.7 sodium ion channel present on neurons, which is an important component of the pain response. The researchers encoded a vers...
Source: Medgadget - August 25, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Pain Management chronic pain nyu Source Type: blogs

Navigating the broken medical system: challenges faced by foreign medical graduates
As I sit here contemplating the beginning of this unsent letter, I find myself questioning its intended recipient and purpose. The truth is, I don’t have the answers just yet. Perhaps, by the end of these few paragraphs, some clarity will emerge. When I left my home country to come to the United States, I Read more… Navigating the broken medical system: challenges faced by foreign medical graduates originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 25, 2023 Category: General Medicine Authors: Tags: Physician Hospital-Based Medicine Source Type: blogs

The Longevity-Associated Variant of BPIFB4 Reduces Heart Disease Severity
Few human longevity-associated gene variants are replicated in multiple patient populations. One of those is a variant of BPIFB4, that appears to improve immune function and lower inflammation by adjusting the behavior of macrophage cells of the innate immune system. Delivering the variant to mice using a gene therapy has similar effects. It may well operate via other mechanisms as well, however. Few proteins in a living cell turn out to have only one purpose. In today's open access paper, researchers report that the BPIFB4 variant reduces the severity of coronary artery disease in humans and mice. Delivering the va...
Source: Fight Aging! - August 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Microsoft CEO Sees Generative AI as Transformative as Relational Databases
At Epic’s 2023 User Group Meeting (#epicugm), Microsoft CEO Satya Nadella and Sumit Rana, Senior Vice President at Epic sat down for a one-on-one conversation about generative AI. Their conversation was fascinating on two levels. First, it was surprising that they did not speak to the deeper partnership between the two companies that was announced in the hours ahead of their time on stage. Second, was the blink-and-you-missed-it difference between how the two men view generative AI. Deeper Partnership Between Epic and Microsoft Early on Tuesday morning an announcement was made about the expanded collaboration between...
Source: EMR and HIPAA - August 25, 2023 Category: Information Technology Authors: Colin Hung Tags: AI/Machine Learning C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Azure ChatGPT Epic Epic UGM Generative AI Healthcare AI Judy Faulkner Microsoft Nuance DAX Satya Nadella Sumit Rana Source Type: blogs

What Trend in RCM Are You Keeping Your Eye on Right Now and Why?
With the current economic uncertainty and challenges, a lot of healthcare organization’s financial statuses are dealing with some challenges. As a result, the world of healthcare is also constantly adapting and coming up with new Revenue Cycle Management solutions. But if everything is constantly changing, how are we supposed to keep track of what solution is best for our organizations? In search of that answer, we reached out to our wickedly smart Healthcare IT Today Community to see what trends in RCM they are keeping their eyes on and why. We’ve compiled all of their answers together in the video down below....
Source: EMR and HIPAA - August 25, 2023 Category: Information Technology Authors: Grayson Miller Tags: AI/Machine Learning C-Suite Leadership Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Revenue Cycle Management AHIMA Amanda Devlin Cedar Chartis ChartSwap Experian Health Future Fami Source Type: blogs

Exploring how thoughts shape emotions and perception PODCAST
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Miguel Villagra, a hospitalist, as we explore how our thoughts shape emotions, dissecting cognitive distortions like all-or-nothing thinking, overgeneralization, and more. Discover strategies to break free from negative loops, challenge assumptions, and cultivate a balanced perspective. Learn how awareness of our thoughts can Read more… Exploring how thoughts shape emotions and perception [PODCAST] originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 24, 2023 Category: General Medicine Authors: Tags: Podcast Psychiatry Source Type: blogs

PF4 Released by Platelets a Common Factor in Multiple Interventions Known to Reduce Neuroinflammation
Chronic inflammation of brain tissue is characteristic of aging and neurodegenerative conditions. The worse the inflammation, the worse the outcome. Lasting, unresolved inflammation in the absence of the usual causes of inflammation such as injury or infection occurs in aged tissues for a variety of reasons, including the pro-inflammatory signaling of senescent cells and triggering of innate immune responses by the mislocalization of mitochondrial DNA that occurs as a result of mitochondrial dysfunction. Current methods of suppressing inflammation are crude, a matter of blocking specific inflammatory signals passing betwee...
Source: Fight Aging! - August 24, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

THCB 20th Birthday Classic: Value-based care – no progress since 1997?
As the 20th Birthday rolls on I thought I’d bring out a more recent piece first published in October 2020, albeit one that relies heavily on 25 year old data to make a point. This is some evidence to back up Jeff Goldsmith’s comment on the original that for all the talk “ ‘Value based” payment is a religious movement, not a business trend’ ” By the way, Humana updated these numbers last year and there’s been basically no change — Matthew Holt By MATTHEW HOLT Humana is out with a report saying that its Medicare Advantage members who are covered by value-based care (VBC) ar...
Source: The Health Care Blog - August 24, 2023 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care Capitation Humana Medicare Advantage VBC Source Type: blogs

Ming Lei Departs Division for Research Capacity Building
It’s with mixed emotions that I share that Ming Lei left our Division for Research Capacity Building (DRCB) earlier this month to become senior associate vice president for research and graduate education at West Virginia University (WVU) Health Sciences. Ming also joined the faculty in WVU’s School of Medicine as vice dean for research and a professor in the department of microbiology, immunology, and cell biology. Ming has been part of the NIH community since 2008, serving in key positions at the National Cancer Institute before joining NIGMS in 2018. During his tenure in DRCB, Ming led numerous initiatives to...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 24, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages NIGMS Staff News Source Type: blogs

Provider-Led Value-Based Care at Vanderbilt University Medical Center
In this video, two experts at Vanderbilt University Medical Center (VUMC) in Tennessee describe how they implemented value-based care from the provider’s point of view. They distinguish provider-led from payer-led bundles, reveal how VUMC had to evolve, and describe which medical conditions are most appropriate for value-based care. Value-based care is not new. Kaiser Permanente, a well-known employer-based provider, started in 1945. Even earlier, in 1937, the member-owned Group Health Association (GHA) formed in Washington, D.C. But in the current wave of taking on risk, payers dominated. According to C.J. Stimson, ...
Source: EMR and HIPAA - August 24, 2023 Category: Information Technology Authors: John Lynn Tags: Administration Analytics/Big Data Clinical Health IT Company Healthcare IT Hospital - Health System Revenue Cycle Management Brittany Cunningham CJ Stimson Healthcare IT Video Interviews Healthcare Scene Featured HFMA HFMA 2023 H Source Type: blogs

Navigating Correlation and Causation with Life Sciences in the Age of AI
The following is a guest article by Alex Long, Head of Life Sciences Sales Strategy at Dell Technologies In science, avoiding correlation without causation is a cornerstone of research methodology. This fundamental principle ensures that scientific conclusions are grounded in evidence rather than coincidental associations. However, as we venture into the Artificial Intelligence (AI) age, a new challenge emerges – that of “Correlation, not Creation.” A classic example highlighting the distinction between correlation and causation is the seemingly bizarre connection between ice cream sales and swimming acci...
Source: EMR and HIPAA - August 24, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AI Hallucination Alex Long Correlation vs Causation Dell Technologies Generative AI Healthcare Scene Featured Human Source Type: blogs

The medical establishment ’s fight for and against diversity
The recent ruling of the Supreme Court of the United States (SCOTUS) to eliminate race-conscious decision-making from college admissions is being openly challenged by the medical establishment. The American Association of American Medical Colleges (AAMC), the Medical Board of California, and the John A. Burns School of Medicine (JABSOM) at the University of Hawaii (among others) Read more… The medical establishment’s fight for and against diversity originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 24, 2023 Category: General Medicine Authors: Tags: Education Medical school Source Type: blogs

The ChatGPT Revolution – Here ’s Our New Book On Generative AI In Healthcare
Artificial intelligence (AI) has been the dominant topic in medicine and healthcare for years as these fields have become more and more technology-dependent. Then, in November 2022, generative AI stormed onto the scene and captured the attention of the masses. The release of ChatGPT finally meant that AI was not a tool for a handful of developers and researchers, but millions of people could start using it in practice. Our latest ebook covers this technological revolution. From the onset, we at The Medical Futurist have been diligently covering all news, studies, and announcements to help patients, healthcare prof...
Source: The Medical Futurist - August 24, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF AI AI in medicine artificial intelligence ChatGPT generative AI in medicine Med-PaLM multimodal AI Source Type: blogs