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Condition: Rhabdomyolysis
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Total 403 results found since Jan 2013.
Temporary hypothyroidism in severe crush syndrome: a potential novel entity
CONCLUSIONS: In severe forms of crush syndrome, temporary hypothyroidism might be seen. The exact mechanism underlying this entity is not well-known. Further clinical and experimental trials should be conducted to illuminate the mechanism of disrupted thyroid hormonogenesis in crush syndrome victims.PMID:37596376 | DOI:10.1007/s42000-023-00475-1
Source: Hormones - August 18, 2023 Category: Endocrinology Authors: Ahmet Burak Dirim Gamze Ergun Sezer Emine Uzun Murvet Yilmaz Source Type: research
Genes, Vol. 14, Pages 1393: NGS-Based Genetic Analysis in a Cohort of Italian Patients with Suspected Inherited Myopathies and/or HyperCKemia
Conclusion These data confirm the high genetic heterogeneity of hyperCKemia and metabolic myopathies. The reduced diagnostic yield suggests the existence of additional genes associated with this condition but also allows speculation that a significant number of cases presenting with hyperCKemia or muscle symptoms are due to extrinsic, not genetic, factors.
Source: Genes - July 2, 2023 Category: Genetics & Stem Cells Authors: Federica Invernizzi Rossella Izzo Isabel Colangelo Andrea Legati Nadia Zanetti Barbara Garavaglia Eleonora Lamantea Lorenzo Peverelli Anna Ardissone Isabella Moroni Lorenzo Maggi Silvia Bonanno Laura Fiori Daniele Velardo Francesca Magri Giacomo P. Comi D Tags: Article Source Type: research
Development and validation of an eco-friendly HPLC –UV method for determination of atorvastatin and vitamin D3 in pure form and pharmaceutical formulation
Statin-associated muscle symptoms are considered as obvious adverse effects of prolonged statin therapy such as myopathy, myalgia, and rhabdomyolysis. These side effects are associated with vitamin D3 deficiency ...
Source: Chemistry Central Journal - June 20, 2023 Category: Chemistry Authors: Khaled Maged, Magda M. El-Henawee and Soad S. Abd El-Hay Tags: Research Source Type: research
Case report: Mitochondrial trifunctional protein deficiency caused by HADHB gene mutation (c.1175C > T) characterized by higher brain dysfunction followed by neuropathy, presented gadolinium enhancement on brain imaging in an adult patient
Mitochondrial trifunctional protein (MTP) deficiency is an autosomal recessive disorder caused by impaired metabolism of long-chain fatty acids (LCFAs). Childhood and late-onset MTP deficiency is characterized by myopathy/rhabdomyolysis and peripheral neuropathy; however, the features are unclear. A 44-year-old woman was clinically diagnosed with Charcot-Marie-Tooth disease at 3 years of age due to gait disturbance. Her activity and voluntary speech gradually decreased in her 40s. Cognitive function was evaluated and brain imaging tests were performed. The Mini-Mental State Examination and frontal assessment battery scores...
Source: Frontiers in Neurology - June 13, 2023 Category: Neurology Source Type: research
Can coenzyme Q10 alleviate the toxic effect of fenofibrate on skeletal muscle?
In conclusion, treatment with CoQ10 improved muscular structure by suppressing oxidative stress, att enuating inflammation, and inhibiting apoptosis.
Source: Histochemistry and Cell Biology - June 4, 2023 Category: Biomedical Science Source Type: research
Expanding the phenotype of DNMT3A as a cause a congenital myopathy with rhabdomyolysis
Tatton-Brown-Rahman syndrome (TBRS; MIM 615879) is characterized by tall stature, a distinctive facial appearance, and impaired intellectual development[1]. Characteristic physical features include low set eyebrows, narrow palpebral fissures, pes planus, hypermobile joints and kyphoscoliosis. TBRS is also known as DNMT3A-overgrowth syndrome[2] and is associated with increased susceptibility to the development of acute myeloid leukemia (AML; MIM: 601626)[3]. Recently, autistic traits were shown to be prevalent in a series of TBRS patients[4].
Source: Neuromuscular Disorders - April 4, 2023 Category: Neurology Authors: Roula Ghaoui, Thuong T. Ha, Jennifer Kerkhof, Haley McConkey, Song Gao, Milena Babic, Rob King, Gianina Ravenscroft, Barbara Kocyzek, Sophia Otto, Nigel G. Laing, Hamish Scott, Bekim Sadikovic, Karin S. Kassahn Tags: Case report Source Type: research
Statin associated Muscular Adverse Effects
CONCLUSION: Early recognition of muscle symptoms is required to prevent rhabdomyolysis. Further researchare needed to completely elucidate the pathophysiology of statin-induced muscular adverse effects.PMID:36847228 | DOI:10.2174/1574886318666230227143627
Source: Current Drug Safety - February 27, 2023 Category: Drugs & Pharmacology Authors: Rania Kammoun Ons Charfi Ghozlane Lakhoua Ahmed Zaiem Riadh Daghfous Sarrah Kastalli Imen Aouinti Sihem El Aidli Source Type: research
What to Know if Your Doctor Put You on Statins to Lower Cholesterol
High cholesterol is a prime example of having too much of a good thing. Our bodies naturally make this substance in the liver and then transport it throughout the body for multiple functions, including hormone regulation, cell tissue regeneration, and vitamin absorption. When the system is working well, cholesterol can boost overall health. But when a certain type called low-density lipoprotein—LDL, sometimes dubbed the “bad” kind—is overproduced, not only does it block the “good” kind called high-density lipoprotein (HDL), but it can also begin to accumulate in the arteries and form thi...
Source: TIME: Health - January 25, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news
Drugs That Interact With Colchicine Via Inhibition of Cytochrome P450 3A4 and P-Glycoprotein: A Signal Detection Analysis Using a Database of Spontaneously Reported Adverse Events (FAERS)
CONCLUSION AND RELEVANCE: This study identifies numerous safety signals for colchicine and CYP3A4/P-gp inhibitor drugs. Avoiding the interaction or monitoring for toxicity in patients when co-prescribing colchicine and these agents is highly recommended.PMID:36688283 | DOI:10.1177/10600280221148031
Source: The Annals of Pharmacotherapy - January 23, 2023 Category: Drugs & Pharmacology Authors: Ainhoa G ómez-Lumbreras Richard D Boyce Lorenzo Villa-Zapata Malinda S Tan Philip D Hansten John Horn Daniel C Malone Source Type: research
