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Condition: Dermatomyositis
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Total 989 results found since Jan 2013.
Rapid and sustained response to JAK inhibition in a child with severe MDA5 + juvenile dermatomyositis
Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood. Amyopathic or hypomyopathic courses have been described.
Source: Pediatric Rheumatology - September 19, 2023 Category: Rheumatology Authors: Timmy Strauss, Claudia G ünther, Anja Schnabel, Christine Wolf, Gabriele Hahn, Min Ae Lee-Kirsch and Normi Brück Tags: Case Report Source Type: research
Narrowband Intense Pulsed Light Treatment for Refractory Facial Rash Associated with Dermatomyositis
We present a case of cutaneous dermatomyositis that was successfully treated with narrowband intense pulsed light.PMID:37719932 | PMC:PMC10504899 | DOI:10.2147/CCID.S426762
Source: Clinical, Cosmetic and Investigational Dermatology - September 18, 2023 Category: Dermatology Authors: Yuxin Zheng Suiqing Cai Source Type: research
Cancer-associated regional ischemic myopathy: a rare myopathy
Paraneoplastic myopathies are often inflammatory or necrotizing, and can be associated with specific antibodies.[1] Regional ischemic immune myopathy (RIIM) is a rare disorder attributed to muscle vasculopathy and considered paraneoplastic.[2] Contrary to dermatomyositis, which is associated with complement mediated muscle microangiopathy, capillary depletion, perifascicular pathology and sometimes muscle ischemia,[3] RIIM is characterized by regional necrosis in border zones between damaged perimysial vessels.
Source: Neuromuscular Disorders - September 17, 2023 Category: Neurology Authors: Andre Granger, Pannathat Soontrapa, Christopher J. Klein, Margherita Milone Source Type: research
Two cases of dermatomyositis associated with neuroendocrine tumors
AbstractDermatomyositis is an idiopathic inflammatory myopathy with cutaneous manifestations, which is associated with several types of malignancies, yet it has been rarely linked to neuroendocrine tumors (NETs). Here we report two cases of dermatomyositis associated with NETs of differing primary sites. Case 1: A 46-year-old female presented with a facial rash and proximal muscle weakness of both extremities. Investigations revealed elevated creatine kinase (CK) and positive anti-transcriptional intermediary factor 1- γ antibody (TIF1γ). The patient had been diagnosed with dermatomyositis and underwent a total body CT s...
Source: International Cancer Conference Journal - August 31, 2023 Category: Cancer & Oncology Source Type: research
Pyomyositis Secondary to Localized Cellulitis in a Dermatomyositis Patient: A Case Report and Review of Infectious Complications in Dermatomyositis
Clin Cosmet Investig Dermatol. 2023 Aug 11;16:2201-2209. doi: 10.2147/CCID.S417772. eCollection 2023.ABSTRACTDermatomyositis (DM) is an autoimmune disorder characterized by proximal muscle weakness and distinct cutaneous features. Unfortunately, infection is a frequent and potentially life-threatening complication in patients with DM. Here, we present a case of pyomyositis in a patient with DM resulting from localized cellulitis. The patient also presented with subcutaneous calcification nodules and dermatomyositis-associated lipodermatosclerosis nodules. To our knowledge, there have been no reports of pyomyositis in patie...
Source: Clinical, Cosmetic and Investigational Dermatology - August 17, 2023 Category: Dermatology Authors: Xingwei Zhang Xiaoyan Lyu Source Type: research
Increased serum soluble interleukin-2 receptor levels in dermatomyositis are associated with Th17/Treg immune imbalance
This study highlights the potential utility of serum sIL-2R levels as a valuable biomarker for assessing disease activity and liver involvement in dermatomyositis. Elevated serum concentrations of sIL-2R were observed in patients with DM, exhibiting significant associations with Th17 cell populations and Th17/ Treg ratios. These findings indicate that sIL-2R may be implicated in the immunopathogenesis of DM, thereby warranting further investigation to elucidate its role in the disease process.
Source: Clinical and Experimental Medicine - August 2, 2023 Category: Research Source Type: research
Differences in muscle magnetic resonance imaging findings between anti-signal recognition particle antibody-positive myopathy and anti-aminoacyl-tRNA synthetase antibody-positive myositis
CONCLUSIONS: A comparison of thigh MRI between anti-SRP myopathy and anti-ARS myositis showed different findings and lesion sites reflecting the different pathophysiology that may contribute to their diagnosis.PMID:37497714 | DOI:10.55563/clinexprheumatol/fjfkfs
Source: Clinical and Experimental Rheumatology - July 27, 2023 Category: Rheumatology Authors: Masatoshi Kimura Ayako Aizawa Risa Kudou Yuki Rikitake Chihiro Iwao Mao Rikitake Kousho Iwao Yumi Kariya Takeshi Kawaguchi Motohiro Matsuda Shunichi Miyauchi Ichiro Takajo Kunihiko Umekita Source Type: research
