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Specialty: Rheumatology

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Total 637 results found since Jan 2013.

Rapid and sustained response to JAK inhibition in a child with severe MDA5  + juvenile dermatomyositis
Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood. Amyopathic or hypomyopathic courses have been described.
Source: Pediatric Rheumatology - September 19, 2023 Category: Rheumatology Authors: Timmy Strauss, Claudia G ünther, Anja Schnabel, Christine Wolf, Gabriele Hahn, Min Ae Lee-Kirsch and Normi Brück Tags: Case Report Source Type: research

Myositis after SARS-CoV-2 vaccination occurs more frequently than assumed and is probably causally related
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1601.ABSTRACTWe read with interest the article by Camargo-Coronel et al. reporting on a systematic review of patients with idiopathic, inflammatory myopathy developing after anti-SARS-CoV-2 vaccinations.PMID:37721345 | DOI:10.4081/reumatismo.2023.1601
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: J Finsterer A S MohanaSundaram F Scorza Source Type: research

Immunopathological features of myopathy associated with small-to-medium-sized vessel vasculitis and differences from autoimmune myositis
CONCLUSIONS: Patients with vasculitis demonstrated mild myofiber damage based on the lower involvement of CD56/NCAM-expressing myofibers compared to those with AIM. Complement component deposits on the vessel walls and hypervascularity in the endomysium areas may be immunopathological features of vasculitic myopathy.PMID:37706291 | DOI:10.55563/clinexprheumatol/hpoapl
Source: Clinical and Experimental Rheumatology - September 14, 2023 Category: Rheumatology Authors: Shun Nomura Yasuhiro Shimojima Takanori Ichikawa Daigo Miyazaki Akinori Uruha Dai Kishida Yoshiki Sekijima Source Type: research

Immune ‐mediated necrotizing myopathy with concomitant development of Kikuchi–Fujimoto disease
AbstractImmune-mediated necrotizing myopathy (IMNM) is a distinct type of idiopathic inflammatory myositis, pathologically characterized by myofiber necrosis and degeneration in the absence of lymphocyte infiltration. Herein, we present a case of IMNM with concomitant development of Kikuchi –Fujimoto disease (KFD), characterized by histiocytic necrotizing lymphadenitis, in a 36-year-old woman who had a treatment history for rheumatoid arthritis (RA). Treatment with oral prednisolone and tacrolimus as immunosuppressants resulted in the remission of the skeletomuscular involvement and lymphadenopathy. To the best of our kn...
Source: International Journal of Rheumatic Diseases - September 1, 2023 Category: Rheumatology Authors: Takanori Ichikawa, Ryo Furukawa, Yasuhiro Shimojima, Yumi Hoshino, Dai Kishida, Yoshiki Sekijima Tags: CASE REPORT Source Type: research

Association between self-reported race and ethnicity and myositis-specific autoantibodies in a diverse cohort of patients with inflammatory myopathy
AbstractMyositis-specific autoantibodies (MSAs) are highly specific biomarkers for idiopathic inflammatory myopathies (IIMs). We investigated whether self-reported race and ethnicity were associated with the presence of specific MSAs. Charts of patients with IIM seen at 3 large healthcare systems in the same US city were reviewed. Demographic data and MSA test results were abstracted. Associations between race and ethnicity and presence of MSAs were analyzed using bivariate analysis and further characterized using separate unadjusted and adjusted logistic regression models. One hundred twenty-one subjects were included (19...
Source: Clinical Rheumatology - August 4, 2023 Category: Rheumatology Source Type: research

Value of the HFA-PEFF diagnostic algorithms for heart failure with preserved ejection fraction to the inflammatory myopathy population
The HFA-PEFF score has been validated to hold great diagnostic and prognostic utility for heart failure with preserved ejection fraction (HFpEF). Idiopathic inflammatory myopathy (IIM) is recognized as one of ...
Source: Arthritis Research and Therapy - August 4, 2023 Category: Rheumatology Authors: Yunjing Shi, Hao Zhang, Zeping Qiu, Yanjia Chen, Xiuxiu Su, Huihui Chi, Tienan Feng, Yue Sun, Honglei Liu, Xiaobing Cheng, Junna Ye, Hui Shi, Qiongyi Hu, Zhuochao Zhou, Jianfen Meng, Jialin Teng & hellip; Tags: Research Source Type: research

Association between self-reported race and ethnicity and myositis-specific autoantibodies in a diverse cohort of patients with inflammatory myopathy
AbstractMyositis-specific autoantibodies (MSAs) are highly specific biomarkers for idiopathic inflammatory myopathies (IIMs). We investigated whether self-reported race and ethnicity were associated with the presence of specific MSAs. Charts of patients with IIM seen at 3 large healthcare systems in the same US city were reviewed. Demographic data and MSA test results were abstracted. Associations between race and ethnicity and presence of MSAs were analyzed using bivariate analysis and further characterized using separate unadjusted and adjusted logistic regression models. One hundred twenty-one subjects were included (19...
Source: Clinical Rheumatology - August 4, 2023 Category: Rheumatology Source Type: research

Differences in muscle magnetic resonance imaging findings between anti-signal recognition particle antibody-positive myopathy and anti-aminoacyl-tRNA synthetase antibody-positive myositis
CONCLUSIONS: A comparison of thigh MRI between anti-SRP myopathy and anti-ARS myositis showed different findings and lesion sites reflecting the different pathophysiology that may contribute to their diagnosis.PMID:37497714 | DOI:10.55563/clinexprheumatol/fjfkfs
Source: Clinical and Experimental Rheumatology - July 27, 2023 Category: Rheumatology Authors: Masatoshi Kimura Ayako Aizawa Risa Kudou Yuki Rikitake Chihiro Iwao Mao Rikitake Kousho Iwao Yumi Kariya Takeshi Kawaguchi Motohiro Matsuda Shunichi Miyauchi Ichiro Takajo Kunihiko Umekita Source Type: research