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Total 32 results found since Jan 2013.

Infraclavicular Catheter in MELAS Syndrome for Analgesic Purposes
M Onay, T Tanyel Kiremitçi, G Erdoğan Kayhan, D İlhan Algın, MS GüleçNeurology India 2023 71(4):764-766 MELAS syndrome is defined as mitochondrial myopathy accompanied by encephalopathy, lactic acidosis, myoclonus, stroke-like episodes. It has a progressive course, multi-systemic effects and severe complications. Myoclonic contractions are unresponsive to many anti-epileptic drugs; these contractions and spasms may lead to severe pain. Systemic analgesic drugs are not sufficient to control pain. Therefore, continuous brachial plexus blockage may be pr...
Source: Neurology India - August 18, 2023 Category: Neurology Authors: M Onay T Tanyel Kiremit & #231;i G Erdo & #287;an Kayhan D & #304;lhan Alg & #305;n MS G & #252;le & #231; Source Type: research

Neuromuscular Complications of Radiation Fibrosis Syndrome
AbstractPurpose of ReviewRadiation fibrosis syndrome (RFS) can adversely affect the function and quality of life of cancer survivors. This paper summarizes the neuromuscular complications of RFS and common clinical manifestations in the patient groups most commonly affected including those treated for Hodgkin ’s lymphoma, head and neck cancer, and breast cancer.Recent FindingsA wide range of clinical sequelae can be seen in RFS including myelopathy, radiculopathy, plexopathy, neuropathy, myopathy, or any combinations of these disorders, a phenomenon termed “myelo-radiculo-plexo-neuro-myopathy. ” Shoulder dysfunction,...
Source: Current Physical Medicine and Rehabilitation Reports - April 6, 2023 Category: Rehabilitation Source Type: research

Immune Checkpoint Inhibitor–Associated Myositis: A Distinct Form of Inflammatory Myopathy
Research on the relationship between inflammatory myopathy and malignancy has grown considerably within the last century. Now, the burgeoning field of inflammatory myopathy has yet another player in the mix: immune checkpoint inhibitor–associated myositis (ICI myositis). Immune checkpoint inhibitor–associated myositis is indicated by clinical diagnosis of inflammatory myopathy after initiation of immune checkpoint inhibitor for cancer management. Current literature reflects low prevalence but high mortality associated with ICI myositis, especially when involving myasthenia gravis and myocarditis. Immune checkpoint inhi...
Source: JCR: Journal of Clinical Rheumatology - October 1, 2022 Category: Rheumatology Tags: Review Source Type: research

Immune Checkpoint Inhibitor-Associated Myositis: A Distinct Form of Inflammatory Myopathy
J Clin Rheumatol. 2022 Jun 14. doi: 10.1097/RHU.0000000000001874. Online ahead of print.ABSTRACTResearch on the relationship between inflammatory myopathy and malignancy has grown considerably within the last century. Now, the burgeoning field of inflammatory myopathy has yet another player in the mix: immune checkpoint inhibitor-associated myositis (ICI myositis). Immune checkpoint inhibitor-associated myositis is indicated by clinical diagnosis of inflammatory myopathy after initiation of immune checkpoint inhibitor for cancer management. Current literature reflects low prevalence but high mortality associated with ICI m...
Source: Clinical Lung Cancer - June 13, 2022 Category: Cancer & Oncology Authors: Didem Saygin Nilasha Ghosh Pankti Reid Source Type: research

Diabetes mellitus tendino-myopathy: epidemiology, clinical features, diagnosis and management of an overlooked diabetic complication
AbstractTendino-myopathy, an unexplored niche, is a non-vascular unstated T2DM complication, which is largely disregarded in clinical practice, thus, we aim to explore it in this review. Literature search using published data from different online resources. Epidemiologically, reported prevalence varies around 10 –90%, which is marked variable and unreliable. Clinically, diabetic tendino-myopathy is typified by restriction of movement, pain/tenderness, cramps and decreased functions. Moreover, myopathy is characterized by muscle atrophy, weakness and ischemia, and tendinopathy by deformities and reduced fu nctions/precis...
Source: Acta Diabetologica - June 3, 2022 Category: Endocrinology Source Type: research

Adrenal carcinoma: a case report
ConclusionThis case illustrates a rare presentation of adrenal carcinoma. Awareness of this presentation may facilitate early evaluation and management.
Source: Journal of Medical Case Reports - May 30, 2022 Category: General Medicine Source Type: research

Diabetes mellitus tendino-myopathy: epidemiology, clinical features, diagnosis and management of an overlooked diabetic complication
AbstractTendino-myopathy, an unexplored niche, is a non-vascular unstated T2DM complication, which is largely disregarded in clinical practice, thus, we aim to explore it in this review. Literature search using published data from different online resources. Epidemiologically, reported prevalence varies around 10 –90%, which is marked variable and unreliable. Clinically, diabetic tendino-myopathy is typified by restriction of movement, pain/tenderness, cramps and decreased functions. Moreover, myopathy is characterized by muscle atrophy, weakness and ischemia, and tendinopathy by deformities and reduced fu nctions/precis...
Source: Acta Diabetologica - March 15, 2022 Category: Endocrinology Source Type: research

Thymoma may explain the confusion: a case report
ConclusionThis case illustrates an exceptional association of two entities and the difficulty encountered during their diagnosis and treatment. The management of these two diseases is different, so it is essential to recognize this concomitant presentation.
Source: Journal of Medical Case Reports - December 16, 2021 Category: General Medicine Source Type: research

Diagnosis and management of X-linked hypophosphatemia in children and adolescent in the Gulf Cooperation Council countries
ConclusionThis guideline was developed to provide an approach to the diagnosis of XLH, especially where there is no family history of the disease, and that other related conditions are not mistaken for XLH. We also guide the medical management of XLH with conventional treatment and with burosumab, a recombinant human IgG1 monoclonal antibody to FGF23.
Source: Archives of Orthopaedic and Trauma Surgery - March 4, 2021 Category: Orthopaedics Source Type: research

Advances in the management of statin myopathy
Purpose of review Statins are highly effective therapies for reducing low-density lipoprotein cholesterol and preventing cardiovascular events. However, many patients taking statins experience statin-associated muscle symptoms. In the current manuscript, we review algorithms to define statin intolerance and approaches to optimize cardiovascular risk reduction and reduce the nocebo effect among individuals reporting statin-associated muscle pain. Recent findings Patients with statin intolerance have a higher cardiovascular event risk. These data underscore the need to apply clinical strategies that improve treatm...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - March 2, 2021 Category: Endocrinology Tags: LIPIDS: Edited by Gerald F. Watts Source Type: research

Chest Pain, Statins, Troponin Elevation, and Myopathy: A Diagnostic and Management Dilemma
A 64-year-old man with known ischemic heart disease and previous myocardial infarction and stent implantation presented to the Emergency Department with bilateral arm pain and chest discomfort with mixed features. He described a dull, central sensation within the chest, which did not radiate to the neck, jaw, or back. Additionally, he had a 3-week history of fatigue and intermittent myalgias, predominantly affecting the shoulders on exertion. Cardiac risk factors included hypertension and hypercholesterolemia.
Source: The American Journal of Medicine - November 8, 2020 Category: General Medicine Authors: Daniel T. Tardo, Alana Bruce, Alice Pearlman, Louis W. Wang, Allan Sturgess, Mark Pitney Tags: Diagnostic Dilemma Source Type: research

Chest pain, statins, troponin elevation and myopathy: A diagnostic and management dilemma
A 64 year old male with known ischemic heart disease and previous myocardial infarction and stent implantation presented to the Emergency Department with bilateral arm pain and chest discomfort with mixed features. He described a dull, central sensation within the chest which did not radiate to the neck, jaw or back. Additionally, he had a three week history of fatigue and intermittent myalgias, predominantly affecting the shoulders on exertion. Cardiac risk factors included hypertension and hypercholesterolemia.
Source: The American Journal of Medicine - November 8, 2020 Category: General Medicine Authors: Daniel T. Tardo, Alana Bruce, Alice Pearlman, Louis W. Wang, Allan Sturgess, Mark Pitney Tags: Diagnostic Dilemma Source Type: research

Comparative Analysis of the Influence of Selected Physical Factors on the Level of Pain in the Course of Temporomandibular Joint Disorders.
Conclusions: Conclusions based on the results of our own research indicate that the selected methods of treatment demonstrate an analgesic effect in terms of the overall discomfort in the course of TMD, and that they may be an alternative pain relief thereby reducing the patient's intake of painkillers. PMID: 33101559 [PubMed - in process]
Source: Pain Research and Management - October 28, 2020 Category: Anesthesiology Authors: Kopacz Ł, Ciosek Ż, Gronwald H, Skomro P, Ardan R, Lietz-Kijak D Tags: Pain Res Manag Source Type: research

Independent risk factors for simvastatin-related myopathy and relevance to different types of muscle symptom
ConclusionsThe absolute risk of simvastatin-related myopathy is low, but individuals at higher risk can be identified to help guide patient management. The lack of association of the myopathy risk score with other muscle symptoms reinforces randomized placebo-controlled evidence that statins do not cause the vast majority of reported muscle symptoms.
Source: European Heart Journal - July 23, 2020 Category: Cardiology Source Type: research

Sudden Cardiac Arrest in an Asymptomatic Zinc Phosphide-Poisoned Patient: A Case Report.
Abstract Zinc phosphide is a gray to black powder mainly used as a rodenticide. In contact with gastric fluid, it releases phosphine which is the main toxic material of this compound. Phosphine interferes with oxidative respiratory cycle of the cells, but is generally expected to manifest its toxicity with prodromal signs and symptoms including abdominal pain, nausea and vomiting, metabolic acidosis, and increased liver function tests. A 64-year-old man was referred to our center with the history of ingestion of three full table spoons of zinc phosphide powder with only a mild GI discomfort. Abdominal X-ray reveal...
Source: Cardiovascular Toxicology - May 24, 2020 Category: Cardiology Authors: Parhizgar P, Forouzanfar R, Hadeiy SK, Zamani N, Hassanian-Moghaddam H Tags: Cardiovasc Toxicol Source Type: research