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Total 32769 results found since Jan 2013.
Sodium-Glucose Cotransporter-2 Inhibitors in Patients with Non-diabetic Chronic Kidney Disease: A Systematic Review
Iran J Kidney Dis. 2023 Jul;17(4):175-183.ABSTRACTSodium-glucose cotransporter-2 (SGLT2) inhibitors modulate kidney function in diabetic chronic kidney disease trials. Furthermore, recent studies have showed their effect on kidney dysfunction in non-diabetic chronic kidney disease (CKD). Here, we focus on the impact of SGLT2 inhibitors on some renal parameters in nondiabetic CKD by discussing completed and ongoing trials. Different databases and search engines of Web of Science, PubMed, Google Scholar, Scopus, SID, and Magiran were searched until November 2022. We included human studies that evaluated the effect of SGLT2 i...
Source: Iranian Journal of Kidney Diseases - August 27, 2023 Category: Urology & Nephrology Authors: Nakisa Rasaei Leila Malekmakan Ghazal Gholamabbas Mina Mashayekh Farshad Hadianfard Mahsa Torabi Source Type: research
Ethical challenges as perceived by nurses in pediatric oncology units
CONCLUSION: From the nurses' perspective, the major ethical challenges in providing ethical care in pediatric oncology units were reducing tension toward promoting the patients' psychological safety, showing respect for the identity and dignity of the children with cancer, and expanding support of the patients' families. By creating the right cultural and professional context and establishing proper protocols, healthcare policymakers and administrators can take effective steps toward eliminating the barriers to providing ethical care.PMID:37624231 | DOI:10.1177/09697330231191278
Source: Nursing Ethics - August 25, 2023 Category: Nursing Authors: Fateme Mohammadi Zeinab Naderi Leila Nikrouz Khodayar Oshvandi Seyedeh Zahra Masoumi Parisa Sabetsarvestani Mostafa Bijani Source Type: research
Molecular Investigation of the Association Among Common Interleukin-6 Polymorphism and Human Papillomavirus Genotypes with Cervical Cancer Among Iranian Women
This study aims to investigate the molecular investigation of HPV infection and its association with the common polymorphism of IL-6 in cervical carcinoma in Iran. This case-control study collected 62 precancerous and cancerous lesions and 62 healthy samples from cancer-free women, subsequent negative colposcopy, and cervical cytology. The frequency of HPV genotypes and the genotyping of IL-6 rs1800795 and rs1800796 were done by different PCR techniques. Results were analyzed using the Epi Info version 7, 2012, with the χ2 test. Compared with cervical intraepithelial neoplasia grade 1 (CINI), the HPV positivity rate is sa...
Source: Cancer Control - August 25, 2023 Category: Cancer & Oncology Authors: Parisa Pourroostaei Ardakani Shadi Abkhiz Kazhaal Sheykhi Kamand Adhami Mojarad Bahareh Rahimi Mohammad Panahi Masoud Hooshmand Source Type: research
The Effect of Mediterranean Diet on Body Composition, Inflammatory Factors, and Nutritional Status in Patients with Cachexia Induced by Colorectal Cancer: A Randomized Clinical Trial
CONCLUSION: It appears that the implementation of the Mediterranean diet might be a strategy to improve nutritional status, quality of life, inflammatory markers, and body composition in patients with colorectal cancer cachexia.TRIAL REGISTRATION: Iranian Registry of Clinical Trials (www.irct.ir); ID: IRCT20211027052884N1.PMID:37621140 | DOI:10.1177/15347354231195322
Source: Cancer Control - August 25, 2023 Category: Cancer & Oncology Authors: Amir Bagheri Farzaneh Asoudeh Saied Rezaei Mohammad Babaei Ahmad Esmaillzadeh Source Type: research
Ethical challenges as perceived by nurses in pediatric oncology units
CONCLUSION: From the nurses' perspective, the major ethical challenges in providing ethical care in pediatric oncology units were reducing tension toward promoting the patients' psychological safety, showing respect for the identity and dignity of the children with cancer, and expanding support of the patients' families. By creating the right cultural and professional context and establishing proper protocols, healthcare policymakers and administrators can take effective steps toward eliminating the barriers to providing ethical care.PMID:37624231 | DOI:10.1177/09697330231191278
Source: Nursing Ethics - August 25, 2023 Category: Nursing Authors: Fateme Mohammadi Zeinab Naderi Leila Nikrouz Khodayar Oshvandi Seyedeh Zahra Masoumi Parisa Sabetsarvestani Mostafa Bijani Source Type: research
Iranian Pharmacist's Experiences of COVID-19 Pandemic: A qualitative study
CONCLUSIONS: Pharmacists dealt with different concerns and challenges during the COVID-19 pandemic. They are one of the main primary care providers and need to be supported by the authorities to maintain their standard level of services.PMID:37619945 | DOI:10.1016/j.pharma.2023.08.009
Source: Annales Pharmaceutiques Francaises - August 24, 2023 Category: Drugs & Pharmacology Authors: Mozhgan Rahnama SeyyedKomeyl Hosseinifar Abdolghani Abdollahimohammad Mandana Moradi Source Type: research
Antibacterial potential of biosynthesized silver nanoparticles using Nepeta sessilifolia Bunge and Salvia hydrangea DC. ex Benth. extracts from the natural habitats of Iran's Rangelands
Nowadays, the use of herbal extracts for the production of nanoparticles has attracted a lot of attention due to the fast reaction, economy, and compatibility with the environment. The aim of the present study...
Source: BMC Complementary and Alternative Medicine - August 24, 2023 Category: Complementary Medicine Authors: Mansureh Ghavam Tags: Research Source Type: research
Evaluation of the antitumor activity of moronecidin (Piscidin)-like peptide in combination with anti-PD-1 antibody against melanoma tumor
CONCLUSION: Treatments with anti-PD-1 inhibitors alone had only a minor effect on tumor size, whereas combination therapy resulted in significant tumor growth control and increased animal survival. MLP therapy combined with anti-PD-1 antibody improves anti-tumor immune response in addition to inducing tumor cell apoptosis. As a result, the evidence suggests that intratumoral injection of MPL can improve anti-PD-1 antibody antitumor response.PMID:37605720 | PMC:PMC10440138 | DOI:10.22038/IJBMS.2023.69639.15166
Source: Cancer Control - August 22, 2023 Category: Cancer & Oncology Authors: Mohsen Mohammadi Amin Moradi Hasan-Abad Ali Ghasemi Source Type: research
Expression levels of foxo-1, p27kip1, mir-27, mir-186 and akt1/akt-p proteins in women with endometrial cancer and hyperplasia: implications for the human reproductive system
CONCLUSIONS: Our findings suggest that FOXO-1, miR-27, miR-186, and Akt1-P/Akt1 protein have the potential to serve as tissue biomarkers for early diagnosis, prognosis, and progression of EC in the human reproductive system.PMID:37601705 | PMC:PMC10439323 | DOI:10.4183/aeb.2023.1
Source: Cancer Control - August 21, 2023 Category: Cancer & Oncology Authors: P Ghaderi S Fallah H R Khaledi A Tehranian F Rahmati S Sheikhhasani Source Type: research
Molecular Status of < em > BRAF < /em > Mutation in Epithelial Ovarian Cancer: An Analysis of 57 Cases in the Northeast of Iran
CONCLUSION: The BRAF mutation is most frequent in borderline tumors but not in invasive serous carcinomas. It seems that 2 different pathways exist for the development of ovarian epithelial neoplasms: one for borderline tumors and the other for high-grade invasive carcinomas. Our study supports this hypothesis. The BRAF mutation is rare in mucinous neoplasms.PMID:37600581 | PMC:PMC10439751 | DOI:10.30699/IJP.2023.554750.2907
Source: Cancer Control - August 21, 2023 Category: Cancer & Oncology Authors: Amirhossein Jafarian Masoumeh Jafaripour Masoumeh Gharib Maryam Salehi Nema Mohamadian Roshan Sare Etemad Khatoone Mirshekar Maryam Sheikhi Masoumeh Heidari Behnaz Ahmadian Zahra Khoshnegah Hossein Ayatollahi Payam Siyadat Source Type: research
