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Antimicrobial resistance of Pseudomonas aeruginosa isolated from patients with pneumonia during the COVID-19 pandemic and pre-pandemic periods in Northeast Brazil
Braz J Med Biol Res. 2023 Jul 21;56:e12726. doi: 10.1590/1414-431X2023e12726. eCollection 2023.ABSTRACTHealthcare-related infections caused by resistant microorganisms are a severe public health problem and are becoming increasingly prevalent in the hospital environment, especially Pseudomonas aeruginosa. This work aimed to evaluate the resistance profile of Pseudomonas aeruginosa to antimicrobials before the COVID-19 pandemic and during the pandemic period. Bacteria strains were obtained from tracheal aspiration, sputum, and bronchoalveolar lavage for diagnosis and phenotypic characterization. Matrix assisted laser-desorp...
Source: Braz J Med Biol Res - July 26, 2023 Category: Research Authors: G P Mesquita M C C Costa M A Silva L G Ara újo B G Vila Nova É J M Castro L C M Castelo Branco R C S da Silva S G Marques A G Abreu Source Type: research

The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease
Mini Rev Med Chem. 2023 Jul 25. doi: 10.2174/1389557523666230725115324. Online ahead of print.ABSTRACTAlongside the prescription of commonly used antivirals, such as acyclovir, remdesivir, oseltamivir, and ciprofloxacin, the most efficient way to prevent or treat communicable diseases is by vaccination. Vaccines have been the most efficient way to prevent or treat highly transmissible infectious agents, such as Ebola, Anthrax, and Dengue Fever. Most epidemics of these highly transmissible infectious agents occur in places, such as South America, Central America, Tropical Asia, and Africa, where the availability of resource...
Source: Mini Reviews in Medicinal Chemistry - July 25, 2023 Category: Chemistry Authors: Anthony Garcia Oliver Grundmann Source Type: research