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Drug: Cipro
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Safety of Antibiotic Irrigations for Acute Exacerbations of Chronic Rhinosinusitis in Patients with Identical Drug Allergies or Adverse Reactions: A Pilot Study
Conclusions: Currently, no prior study has examined whether adverse reactions to a systemic antibiotic also occur when the medication is delivered topically via sinonasal irrigations. Our findings suggest that topical administration of antibiotics may be a safe alternative for patients with adverse effects to the systemic form.PMID:37522348 | DOI:10.1177/01455613231189057
Source: Ear, Nose and Throat Journal - July 31, 2023 Category: ENT & OMF Authors: Hye Rhyn Chung Jessa E Miller Jeffrey D Suh Source Type: research
A novel electrochemical aptasensor based on eco-friendly synthesized titanium dioxide nanosheets and polyethyleneimine grafted reduced graphene oxide for ultrasensitive and selective detection of ciprofloxacin
Anal Chim Acta. 2023 Sep 22;1275:341607. doi: 10.1016/j.aca.2023.341607. Epub 2023 Jul 10.ABSTRACTDeveloping a rapid, sensitive, and efficient analytical method for the trace-level determination of highly concerning antibiotic ciprofloxacin (CIP) is desirable to guarantee the safety of human health and ecosystems. In this work, a novel electrochemical aptasensor based on polyethyleneimine grafted reduced graphene oxide and titanium dioxide (rGO/PEI/TiO2) nanocomposite was constructed for ultrasensitive and selective detection of CIP. Through the in-situ electrochemical oxidation of Ti3C2Tx nanosheets, TiO2 nanosheets with ...
Source: Analytica Chimica Acta - July 31, 2023 Category: Chemistry Authors: Yangguang Zhu Xiufen Li Mengfan Wu Mingjiao Shi Qichen Tian Li Fu Hsu-Sheng Tsai Wan-Feng Xie Guosong Lai Gang Wang Nan Jiang Chen Ye Cheng-Te Lin Source Type: research
Safety of Antibiotic Irrigations for Acute Exacerbations of Chronic Rhinosinusitis in Patients with Identical Drug Allergies or Adverse Reactions: A Pilot Study
Conclusions: Currently, no prior study has examined whether adverse reactions to a systemic antibiotic also occur when the medication is delivered topically via sinonasal irrigations. Our findings suggest that topical administration of antibiotics may be a safe alternative for patients with adverse effects to the systemic form.PMID:37522348 | DOI:10.1177/01455613231189057
Source: Ear, Nose and Throat Journal - July 31, 2023 Category: ENT & OMF Authors: Hye Rhyn Chung Jessa E Miller Jeffrey D Suh Source Type: research
A novel electrochemical aptasensor based on eco-friendly synthesized titanium dioxide nanosheets and polyethyleneimine grafted reduced graphene oxide for ultrasensitive and selective detection of ciprofloxacin
Anal Chim Acta. 2023 Sep 22;1275:341607. doi: 10.1016/j.aca.2023.341607. Epub 2023 Jul 10.ABSTRACTDeveloping a rapid, sensitive, and efficient analytical method for the trace-level determination of highly concerning antibiotic ciprofloxacin (CIP) is desirable to guarantee the safety of human health and ecosystems. In this work, a novel electrochemical aptasensor based on polyethyleneimine grafted reduced graphene oxide and titanium dioxide (rGO/PEI/TiO2) nanocomposite was constructed for ultrasensitive and selective detection of CIP. Through the in-situ electrochemical oxidation of Ti3C2Tx nanosheets, TiO2 nanosheets with ...
Source: Analytica Chimica Acta - July 31, 2023 Category: Chemistry Authors: Yangguang Zhu Xiufen Li Mengfan Wu Mingjiao Shi Qichen Tian Li Fu Hsu-Sheng Tsai Wan-Feng Xie Guosong Lai Gang Wang Nan Jiang Chen Ye Cheng-Te Lin Source Type: research
POPULATION PHARMACOKINETIC MODELING OF THE INFLUENCE OF CHRONIC AND ACUTE BIOFILM-FORMING Pseudomonas aeruginosa LUNG INFECTION ON CIPROFLOXACIN FREE PULMONARY AND EPITHELIAL LINING FLUID CONCENTRATIONS
Eur J Pharm Sci. 2023 Jul 28:106546. doi: 10.1016/j.ejps.2023.106546. Online ahead of print.ABSTRACTWe previously reported that ciprofloxacin (CIP) free lung interstitial concentrations are decreased by biofilm-forming Pseudomonas aeruginosa pulmonary chronic (14 d) infection. To get a better understanding on the influence of infection on CIP lung distribution, in the present study free lung interstitial fluid and epithelial lining fluid (ELF) concentrations were determined by microdialysis in biofilm-forming P. aeruginosa acutely (2 d) and chronically infected (14 d) Wistar rats following CIP 20 mg/kg i.v. bolus dosing. A...
Source: European Journal of Pharmaceutical Sciences - July 30, 2023 Category: Drugs & Pharmacology Authors: Graziela DE Araujo Lock Vict ória Etges Helfer Bruna Bernar Dias Bruna Gaelzer Silva Torres Bibiana Verlindo DE-Ara újo Teresa Dalla-Costa Source Type: research
Whole genome sequencing of Bacillus anthracis isolated from animal in the 1960s, Brazil, belonging to the South America subclade
Comp Immunol Microbiol Infect Dis. 2023 Jul 25;100:102027. doi: 10.1016/j.cimid.2023.102027. Online ahead of print.ABSTRACTBacillus anthracis causes anthrax disease and can affect humans and other animals. This zoonotic disease has an impact on the economic and health aspects. B. anthracis population is divided into three major clades: A (with worldwide distribution), B, and C (restricted to specific regions). Anthrax is most common in agricultural regions of central and southwestern Asia, sub-Saharan Africa, Southern and Eastern Europe, the Caribbean, and Central and South America. Here, we sequenced by short and long rea...
Source: Comparative immunology, microbiology and infectious diseases. - July 30, 2023 Category: Allergy & Immunology Authors: T ânia Sueli de Andrade Carlos Henrique Camargo Karoline Rodrigues Campos Alex Domingos Reis Marlon Benedito do Nascimento Santos Vanessa Nieri Zanelatto Elizabeth Harummyy Takagi Claudio Tavares Sacchi Source Type: research
Antimicrobial resistance of Pseudomonas aeruginosa isolated from patients with pneumonia during the COVID-19 pandemic and pre-pandemic periods in Northeast Brazil
Braz J Med Biol Res. 2023 Jul 21;56:e12726. doi: 10.1590/1414-431X2023e12726. eCollection 2023.ABSTRACTHealthcare-related infections caused by resistant microorganisms are a severe public health problem and are becoming increasingly prevalent in the hospital environment, especially Pseudomonas aeruginosa. This work aimed to evaluate the resistance profile of Pseudomonas aeruginosa to antimicrobials before the COVID-19 pandemic and during the pandemic period. Bacteria strains were obtained from tracheal aspiration, sputum, and bronchoalveolar lavage for diagnosis and phenotypic characterization. Matrix assisted laser-desorp...
Source: Braz J Med Biol Res - July 26, 2023 Category: Research Authors: G P Mesquita M C C Costa M A Silva L G Ara újo B G Vila Nova É J M Castro L C M Castelo Branco R C S da Silva S G Marques A G Abreu Source Type: research
