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Total 9684 results found since Jan 2013.

Challenges in anti-aging medicine-trends in biomarker discovery and therapeutic interventions for a healthy lifespan
J Cell Mol Med. 2023 Aug 23. doi: 10.1111/jcmm.17912. Online ahead of print.ABSTRACTWe are facing a growing aging population, along with increasing pressure on health systems, caused by the impact of chronic co-morbidities (i.e. cancer, cardiovascular and neurodegenerative diseases) and functional disabilities as people age. Relatively simple preventive lifestyle interventions, such as dietary restriction and physical exercise, are important contributors to active and healthy aging in the general population. However, as shown in model organisms or in 'in vitro' conditions, lifestyle-independent interventions may have addit...
Source: Molecular Medicine - August 23, 2023 Category: Molecular Biology Authors: Iuliana Popescu Joris Deelen Maddalena Illario Jan Adams Source Type: research

Glycaemic control and insulin therapy are significant confounders of the obesity paradox in patients with heart failure and diabetes mellitus
CONCLUSION: In patients with HFrEF, a higher BMI is associated with better survival irrespective of concomitant DM. However, insulin treatment and poor glycaemic control make the relationship much weaker.PMID:37608126 | DOI:10.1007/s00392-023-02268-3
Source: Clin Med Res - August 22, 2023 Category: Research Authors: Hanna Fr öhlich Anna Bossmeyer Syed Kazmi Kevin M Goode Stefan Agewall Dan Atar Morten Grundtvig Norbert Frey John G F Cleland Lutz Frankenstein Andrew L Clark Tobias T äger Source Type: research

Ultrasound vs. fluoroscopic guidance in genicular nerve radiofrequency thermocoagulation for chronic knee pain: which one is the future?
CONCLUSIONS: For the radiofrequency thermocoagulation of the genicular nerve, both imaging approaches are available. Ultrasonography guidance appears to be better than fluoroscopy guidance in this technique because of the lower radiation dose and the ability to detect the target location and neighboring tissues more precisely under ultrasonography guidance.PMID:37606117 | DOI:10.26355/eurrev_202308_33280
Source: Pharmacological Reviews - August 22, 2023 Category: Drugs & Pharmacology Authors: G Da ğıstan E G önüllü Source Type: research

Glycaemic control and insulin therapy are significant confounders of the obesity paradox in patients with heart failure and diabetes mellitus
CONCLUSION: In patients with HFrEF, a higher BMI is associated with better survival irrespective of concomitant DM. However, insulin treatment and poor glycaemic control make the relationship much weaker.PMID:37608126 | DOI:10.1007/s00392-023-02268-3
Source: Clin Med Res - August 22, 2023 Category: Research Authors: Hanna Fr öhlich Anna Bossmeyer Syed Kazmi Kevin M Goode Stefan Agewall Dan Atar Morten Grundtvig Norbert Frey John G F Cleland Lutz Frankenstein Andrew L Clark Tobias T äger Source Type: research

Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis
Lancet Glob Health. 2023 Sep;11(9):e1345-e1362. doi: 10.1016/S2214-109X(23)00305-4.ABSTRACTBACKGROUND: The epidemiology of human papillomavirus (HPV) in women has been well documented. Less is known about the epidemiology of HPV in men. We aim to provide updated global and regional pooled overall, type-specific, and age-specific prevalence estimates of genital HPV infection in men.METHODS: We conducted a systematic review and meta-analysis to assess the prevalence of genital HPV infection in the general male population. We searched Embase, Ovid MEDLINE, and the Global Index Medicus for studies published between Jan 1, 1995...
Source: Cancer Control - August 17, 2023 Category: Cancer & Oncology Authors: Laia Bruni Ginesa Albero Jane Rowley Laia Alemany Marc Arbyn Anna R Giuliano Lauri E Markowitz Nathalie Broutet Melanie Taylor Source Type: research

Development of reference material for quality control of uranium analysis in marine sediments
This study was conducted to develop reference material (RM) for the quality control of 238U and 234U analyses in marine sediments. The RM was prepared according to ISO Guides 31, 34, and 35. A homogeneity test of the marine sediment RM was implemented by analyzing two batch samples from ten bottles using multiple acid digestion and alkali fusion, respectively. We found that the 238U and 234U reference values of the RM were 43.0 ± 1.7 Bq kg-1(k=1) and 41.5 ± 1.9 Bq kg-1(k=1), respectively. This marine sediment RM will be useful for the quality control of analytical methods for similar samples and proficiency tests.PMID:37...
Source: Applied Radiation and Isotopes - August 16, 2023 Category: Radiology Authors: Y Jung S H Lee M J Lee Source Type: research

Investigation of the Therapeutic Effect and Mechanism of Holographic Meridian Scraping Therapy on Knee Osteoarthritis
CONCLUSIONS: Combining holographic meridian scraping therapy with celecoxib effectively treats KOA and significantly improves patient conditions, along with reductions in serum TNF-α and IL-1β levels.PMID:37573584
Source: Alternative Therapies in Health and Medicine - August 13, 2023 Category: Complementary Medicine Authors: Yulong Deng Man Zhang Wei Li Shuguo Cui Junge Dong Chenglin Mu Zhiyuan Zheng Jiaxiang Yang Source Type: research