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Vaccination: Malaria Vaccine
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Total 1540 results found since Jan 2013.
Understanding the Intransigence of Malaria in Malawi
Am J Trop Med Hyg. 2022 Oct 11;107(4_Suppl):40-48. doi: 10.4269/ajtmh.21-1263. Print 2022 Oct 11.ABSTRACTDespite the scale-up of interventions against malaria over the past decade, this disease remains a leading threat to health in Malawi. To evaluate the epidemiology of both Plasmodium falciparum infection and malaria disease, the Malawi International Center of Excellence for Malaria Research (ICEMR) has developed and implemented diverse and robust surveillance and research projects. Descriptive studies in ICEMR Phase 1 increased our understanding of the declining effectiveness of long-lasting insecticidal nets (LLINs), t...
Source: Am J Trop Med Hyg - October 13, 2022 Category: Infectious Diseases Authors: Lauren M Cohee Jessy Goupeyou-Youmsi Karl B Seydel Charles Mangani Peter Ntenda Alick Sixpence Rex B Mbewe Alfred Matengeni Shannon Takala-Harrison Edward D Walker Mark L Wilson Themba Mzilahowa Miriam K Laufer Clarissa Valim Terrie E Taylor Don P Mathang Source Type: research
Strategies for malaria vaccination during the COVID-19 pandemic in African countries
Bull World Health Organ. 2022 Oct 1;100(10):582-582A. doi: 10.2471/BLT.21.287472.NO ABSTRACTPMID:36188023 | PMC:PMC9511673 | DOI:10.2471/BLT.21.287472
Source: Bulletin of the World Health Organization - October 3, 2022 Category: International Medicine & Public Health Authors: Kapil Narain Sudhan Rackimuthu Faisal A Nawaz Osaretin Christabel Okonji Henry Ashworth Stefan S Du Plessis Jaffer Shah Source Type: research
Population genetic analysis of Plasmodium falciparum cell-traversal protein for ookinetes and sporozoite among malaria patients from southern Nigeria
Infect Genet Evol. 2022 Sep 28:105369. doi: 10.1016/j.meegid.2022.105369. Online ahead of print.ABSTRACTPlasmodium falciparum immune escape mechanisms affect antigens being prioritized for vaccine design. As a result of the multiple surface antigens the parasite exhibits at different life cycle stages, designing a vaccine that would efficiently boost the immune system in clearing infections has been challenging. The P. falciparum cell-traversal protein for ookinetes and sporozoite (Pfceltos) is instrumental for ookinete traversal of the mosquito midgut and sporozoites invasion of the human liver cells. Pfceltos elicits bot...
Source: Infection, Genetics and Evolution - October 1, 2022 Category: Genetics & Stem Cells Authors: Mary A Oboh Clement Isaac Marissa N Schroeter Olanrewaju B Morenikeji Alfred Amambua-Ngwa Martin M Meremikwu Bolaji N Thomas Source Type: research
Housebreaking Plasmodium parasites leave their fingerprints at the door
Trends Parasitol. 2022 Sep 23:S1471-4922(22)00209-4. doi: 10.1016/j.pt.2022.09.005. Online ahead of print.ABSTRACTProtective antibodies against Plasmodium falciparum merozoite antigens, including EBA-175, can inhibit erythrocyte invasion. New data from Musasia et al. indicate that these antibodies can also trigger antibody-dependent phagocytosis of ring-infected and uninfected erythrocytes and that this correlates with protection from malaria. This provides a new pathway for vaccine design.PMID:36163104 | DOI:10.1016/j.pt.2022.09.005
Source: Trends in Parasitology - September 26, 2022 Category: Parasitology Authors: Lara Bardtke Ian A Cockburn Source Type: research
