Filtered By:
Cancer: Colorectal Cancer

This page shows you your search results in order of date.

Order by Relevance | Date

Total 2560 results found since Jan 2013.

Comparative Studies of Essential Oil Composition and Biological Activities of Callistemon citrinus from western Himalaya
Chem Biodivers. 2023 Sep 20:e202301129. doi: 10.1002/cbdv.202301129. Online ahead of print.ABSTRACTThis work described a comprehensive study to estimate chemical constituents of essential oils (EOs) extracted from different parts of the Callistemon citrinus viz: fruits, leaves and aerial part. The EOs were characterized using physicochemical parameters, and GC-FID/MS. It was observed that among different parts, aerial part has the highest oil yield (0.90%) followed by leaves and fruits. Further, seventeen compounds were characterized, and represented total amount (97.2-99.5%) with domination of monoterpenes (12.5-34.6%) an...
Source: Chemistry and Biodiversity - September 20, 2023 Category: Biochemistry Authors: Sachin Vashisath Smita Kapoor Vandana Kumari Shabana Butt Dinesh Kumar Source Type: research

Impact of adjuvant chemotherapy on long-term overall survival in patients with high-risk stage II colon cancer: a nationwide cohort study
CONCLUSION: 5-year overall survival was significantly higher in patients with high-risk stage II colon cancer treated with adjuvant chemotherapy compared with no chemotherapy. Adjuvant treatment was given to less than half of the patients who were eligible for it.PMID:37725517 | DOI:10.1080/0284186X.2023.2251086
Source: Acta Oncologica - September 19, 2023 Category: Cancer & Oncology Authors: Victoria Rosberg Mikkel Jessen Camilla Qvortrup Henry George Smith Peter-Martin Krarup Source Type: research

Comparison of the short-term and long-term outcomes of three different types of inferior mesenteric artery ligation in left colonic and rectal cancers: a network meta-analysis
AbstractTo perform a network meta-analysis of the literature to assess the short-term and long-term outcomes of three operations for left colon and rectal cancer. Electronic literature searches were performed in the PubMed, Web of Science, EMBASE, and Cochrane Central Register of Controlled Trials databases up to August 2022. A Bayesian network meta-analysis using R software, ADDIS, and Review Manager 5.4 was conducted to compare outcomes of high ligation of the inferior mesenteric artery(IMA),low ligation of the IMA with D2 dissection (LLD2), and low ligation of the IMA with D3 dissection (LLD3). Sensitivity analysis was ...
Source: Updates in Surgery - September 16, 2023 Category: Surgery Source Type: research

Development of a xylose-inducible promoter and riboswitch combination system for manipulating gene expression in < em > Fusobacterium nucleatum < /em >
In this study, we engineered a leakage-free hybrid system for precise gene expression controls in Fusobacterium nucleatum by integrating the xylose-inducible expression system with the theophylline-responsive riboswitch. This innovative method enables concurrent control of target gene expression at both transcription and translation initiation levels. Using luciferase and the indole-producing enzyme tryptophanase (TnaA) as reporters, we demonstrated that the hybrid system displays virtually no observable signal in the absence of inducers. We employed this system to express FtsX, a protein related to fusobacterial cytokines...
Source: Applied and Environmental Microbiology - September 11, 2023 Category: Microbiology Authors: Bibek G C Peng Zhou Arindam Naha Jianhua Gu Chenggang Wu Source Type: research

ICG angiography in prevention of colorectal anastomotic leakage
CONCLUSION: Fluorescent luminescence will qualitatively improve intraoperative diagnosis of hypoperfusion of resection edges. Undoubtedly, this will reduce the incidence of colorectal anastomotic leaks caused by ischemia of large bowel wall.PMID:37682544 | DOI:10.17116/hirurgia202309225
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: A L Bedzhanyan K N Petrenko A A Sumbaev Yu V Frolova V V Nikoda A V Butenko Source Type: research

X-ray-controllable release of carbon monoxide potentiates radiotherapy by ultrastable hybrid nanoreservoirs
Biomaterials. 2023 Sep 2;302:122313. doi: 10.1016/j.biomaterials.2023.122313. Online ahead of print.ABSTRACTCarbon monoxide (CO) exhibits unique abilities in sensitizing cancer radiotherapy (RT). However, the development of a highly stable CO-delivery nanosystem with sustained CO release in tumor tissues and the prevention of CO leakage into normal tissues remains a challenge. Herein, an organic-inorganic hybrid strategy is proposed to create ultrastable CO nanoreservoirs by locking an unstable iron carbonyl (FeCO) prodrug in a stable mesoporous silica matrix. Different from traditional FeCO-loading nanoplatforms, FeCO-bri...
Source: Biomaterials - September 6, 2023 Category: Materials Science Authors: Junna Lu Fangman Chen Xiaochun Xie Ziping Wu Yinglu Chen Yidan Zhang Hui Fang Feixia Ruan Dan Shao Zheng Wang Renjun Pei Source Type: research

Delayed esophageal anastomotic complication and ramucirumab therapy: A case report
In conclusion, this is the only known report of delayed esophageal anastomotic complication associated with ramuciru mab. VEGF inhibitor therapies such as bevacizumab have been associated with late (greater than 3 months postoperative) colorectal anastomotic complications including fistulas and leaks. Risk factors that have been associated are perioperative radiotherapy and history of early postoperative leak. The se findings raise concern whether VEGF inhibitor therapy should be used in post-esophagectomy patients with recurrence if these rare but catastrophic events are likely to be terminal.
Source: Thoracic Cancer - September 5, 2023 Category: Cancer & Oncology Authors: Robert H. Roth, Madison J. Malfitano, Matthew Reilley, Linda W. Martin Tags: CASE REPORT Source Type: research

Low anterior resection syndrome
Ann Gastroenterol Surg. 2023 May 23;7(5):719-724. doi: 10.1002/ags3.12695. eCollection 2023 Sep.ABSTRACTLow anterior resection syndrome (LARS) is the distressful defecatory functional problem after sphincter-saving surgery for rectal cancer. Although the symptoms of fecal urgency, frequency, and incontinence may develop in most of the patients after surgery, there is no definitive treatments for LARS. Multifactorial etiologies and various risk factors have been identified, but the reduction of storage capacity in the rectum is one of the main reasons for LARS. Anal sphincter muscle or nerve damage during rectoanal resectio...
Source: Hand Surgery - September 4, 2023 Category: Surgery Authors: Seung-Bum Ryoo Source Type: research

Minimally invasive colectomies can be performed with similar outcomes to open counterparts for colorectal cancer emergencies: a propensity score matching analysis utilizing ACS-NSQIP
ConclusionsThis study demonstrates that MIS was associated with superior postoperative outcomes compared to open surgery without compromising oncological outcomes in patients undergoing emergency colectomy for colon cancer. Within the matched cohort, MIS was associated with lower rates of mortality, pulmonary complications, ileus, and shorter postoperative length of stay.
Source: Techniques in Coloproctology - August 29, 2023 Category: Surgery Source Type: research

Brand new mom, 28, whose symptoms were brushed off as 'normal part of pregnancy' is diagnosed with stage three COLON CANCER
Kelly Spill, now 31, from New Jersey, was diagnosed with stage 3 colon cancer at age 28 after doctors dismissed her symptoms like rectal bleeding as 'part of pregnancy.'
Source: the Mail online | Health - August 25, 2023 Category: Consumer Health News Source Type: news