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Total 1068 results found since Jan 2013.

The Man Who Thinks He Can Live Forever
In a neat little neighborhood in Venice, Calif., there’s a block of squat, similar homes, filled with mortals spending their finite days on the planet eating pizza with friends, blowing out candles on birthday cakes, and binging late-night television. Halfway down the street, there’s a cavernous black modern box. This is where Bryan Johnson is working on what he calls “the most significant revolution in the history of Homo sapiens.”  [time-brightcove not-tgx=”true”] Johnson, 46, is a centimillionaire tech entrepreneur who has spent most of the last three years in pursuit of a si...
Source: TIME: Health - September 20, 2023 Category: Consumer Health News Authors: Charlotte Alter Tags: Uncategorized feature Source Type: news

Finding Power in My Panic Attacks
Trouble started in the form of rivulets of sweat dampening the waistband of my underwear. It was a bluebird afternoon in Phoenix in December of 2020, mid 60s, desert dry, and my heart was jackhammering against my ribcage. Breathing felt like I was sucking air through a stir straw. A small ABC News crew was arrayed before me, ready to broadcast the report I’d written that day, but with my vision narrowed to a needle’s eye, I could barely see them. I tried to swallow away the sandiness in my mouth but realized I’d forgotten how. [time-brightcove not-tgx=”true”] “I can’t swallow!...
Source: TIME: Health - September 12, 2023 Category: Consumer Health News Authors: Matt Gutman Tags: Uncategorized freelance Source Type: news

Machine-Learning-Aided Prediction of Brain Metastases Development in Non-Small-Cell Lung Cancers
CONCLUSION: Analysis of the importance of input features suggests that the models are learning the relevant relationships between clinical features/development of BM. A higher number of samples is to be prioritized to improve performance. Employed prospectively at initial diagnosis, such models can help select high-risk subgroups for surveillance brain MRI.PMID:37689579 | DOI:10.1016/j.cllc.2023.08.002
Source: Clinical Lung Cancer - September 9, 2023 Category: Cancer & Oncology Authors: Giovanni Vison à Lisa M Spiller Sophia Hahn Elke Hattingen Thomas J Vogl Gabriele Schweikert Katrin Bankov Melanie Demes Henning Reis Peter Wild Pia S Zeiner Fabian Acker Martin Sebastian Katharina J Wenger Source Type: research

Frontal trans-sinusal approach: how I do it
We present our technique to perform a frontal trans-sinusal approach in a patient affected by a large olfactory groove meningioma.Discussion-conclusionThe frontal trans-sinusal approach allows to approach safely lesions of the median anterior cranial fossa. This approach provides lower brain retraction, easier access to olfactory grooves, and earlier tumor devascularization. However, it remains limited to patients with large-sized frontal sinuses and entails some postoperative risks such as mucocele or CSF leak.
Source: Acta Neurochirurgica - September 6, 2023 Category: Neurosurgery Source Type: research

Evaluating the neuroprotective effects of progesterone receptors on experimental traumatic brain injury: The PI3K/Akt pathway
ConclusionAccording to these findings, PRs are acting as critical mediators for the neuroprotective properties of P4 on oxidative stress, pro-inflammatory cytokine levels, and neurological outcomes. PRs also play an important role in regulating the PI3K/p-Akt expression and nongenomic function of P4.
Source: Brain and Behavior - September 4, 2023 Category: Neurology Authors: Ladan Amirkhosravi, Mohammad khaksari, Sedigheh Amiresmaili, Mojgan Sanjari, Parisa Khorasani, Morteza Hashemian Tags: ORIGINAL ARTICLE Source Type: research

In Silico Prediction of Selected Bioactive Compounds Present in Alpinia elegans (C.Presl) K.Schum Seed Oil as Potential Drug Candidates Against Human Cancer Cell Lines
CONCLUSION: The binding energy indicated that the ligands could securely dock to the receptors, thus suggesting that interaction between the ligands and receptors was stable. Results have shown that the compounds are promising candidates against human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.PMID:37642045 | DOI:10.31557/APJCP.2023.24.8.2601
Source: Asian Pacific Journal of Cancer Prevention - August 29, 2023 Category: Cancer & Oncology Authors: Jane Marie N Caasi Raiza Isabel D G Baldoza Mary Sophia C Bauzon Mirabella Anne F Odtohan Librado A Santiago Myla R Santiago-Bautista Source Type: research

Microbial production of docosahexaenoic acid (DHA): biosynthetic pathways, physical parameter optimization, and health benefits
Arch Microbiol. 2023 Aug 29;205(9):321. doi: 10.1007/s00203-023-03666-x.ABSTRACTOmega-3 fatty acids, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and α-linolenic acid (ALA), are essential polyunsaturated fatty acids with diverse health benefits. The limited conversion of dietary DHA necessitates its consumption as food supplements. Omega-3 fatty acids possess anti-arrhythmic and anti-inflammatory capabilities, contributing to cardiovascular health. Additionally, DHA consumption is linked to improved vision, brain, and memory development. Furthermore, omega-3 fatty acids offer protection against vario...
Source: Archives of Microbiology - August 29, 2023 Category: Microbiology Authors: Naaz Abbas Sana Riaz Sania Mazhar Ramsha Essa Maria Maryam Yasar Saleem Quratulain Syed Ishrat Perveen Bakhtawar Bukhari Saira Ashfaq Syed Hussain Imam Abidi Source Type: research

In Silico Prediction of Selected Bioactive Compounds Present in Alpinia elegans (C.Presl) K.Schum Seed Oil as Potential Drug Candidates Against Human Cancer Cell Lines
CONCLUSION: The binding energy indicated that the ligands could securely dock to the receptors, thus suggesting that interaction between the ligands and receptors was stable. Results have shown that the compounds are promising candidates against human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.PMID:37642045 | DOI:10.31557/APJCP.2023.24.8.2601
Source: Asian Pacific Journal of Cancer Prevention - August 29, 2023 Category: Cancer & Oncology Authors: Jane Marie N Caasi Raiza Isabel D G Baldoza Mary Sophia C Bauzon Mirabella Anne F Odtohan Librado A Santiago Myla R Santiago-Bautista Source Type: research

Microbial production of docosahexaenoic acid (DHA): biosynthetic pathways, physical parameter optimization, and health benefits
Arch Microbiol. 2023 Aug 29;205(9):321. doi: 10.1007/s00203-023-03666-x.ABSTRACTOmega-3 fatty acids, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and α-linolenic acid (ALA), are essential polyunsaturated fatty acids with diverse health benefits. The limited conversion of dietary DHA necessitates its consumption as food supplements. Omega-3 fatty acids possess anti-arrhythmic and anti-inflammatory capabilities, contributing to cardiovascular health. Additionally, DHA consumption is linked to improved vision, brain, and memory development. Furthermore, omega-3 fatty acids offer protection against vario...
Source: Archives of Microbiology - August 29, 2023 Category: Microbiology Authors: Naaz Abbas Sana Riaz Sania Mazhar Ramsha Essa Maria Maryam Yasar Saleem Quratulain Syed Ishrat Perveen Bakhtawar Bukhari Saira Ashfaq Syed Hussain Imam Abidi Source Type: research

In Silico Prediction of Selected Bioactive Compounds Present in Alpinia elegans (C.Presl) K.Schum Seed Oil as Potential Drug Candidates Against Human Cancer Cell Lines
CONCLUSION: The binding energy indicated that the ligands could securely dock to the receptors, thus suggesting that interaction between the ligands and receptors was stable. Results have shown that the compounds are promising candidates against human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.PMID:37642045 | DOI:10.31557/APJCP.2023.24.8.2601
Source: Asian Pacific Journal of Cancer Prevention - August 29, 2023 Category: Cancer & Oncology Authors: Jane Marie N Caasi Raiza Isabel D G Baldoza Mary Sophia C Bauzon Mirabella Anne F Odtohan Librado A Santiago Myla R Santiago-Bautista Source Type: research