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Drug: Dexamethasone
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Total 346 results found since Jan 2013.
CircFOXN2 alleviates glucocorticoid- and tacrolimus-induced dyslipidemia by reducing FASN mRNA stability by binding to PTBP1 during liver transplantation
CONCLUSION: CircFOXN2 alleviated the dysregulation of lipid metabolism induced by the combination of TAC and Dex by modulating the PTBP1/FASN axis.PMID:37575056 | DOI:10.1152/ajpcell.00462.2022
Source: Am J Physiol Cell Ph... - August 14, 2023 Category: Cytology Authors: Li-Jian Chen Yang Xin Miao-Xian Yuan Chun-Yi Ji Yu-Ming Peng Qiang Yin Source Type: research
Direct drug milling in organic PLGA solution facilitates the encapsulation of nanosized drug into PLGA microparticles
The objective of this study was to prepare poly(lactide-co-glycolide) (PLGA) microparticles loaded with nanosized drug by combining non-aqueous wet bead milling and microencapsulation. 200 - 300 nm dexamethasone, hydrocortisone and dexamethasone sodium phosphate nanosuspensions were successfully prepared by wet bead milling the drug in dichloromethane using PLGA as a stabilizer. PLGA microparticles loaded with nanosized drugs were then prepared by a solid-in-oil-in-water (S/O/W) solvent evaporation method or solid-in-oil-in-oil (S/O/O) organic phase separation method. The microparticles were characterized by laser diffract...
Source: European Journal of Pharmaceutics and Biopharmaceutics - August 14, 2023 Category: Drugs & Pharmacology Authors: Chenghao Zhang Roland Bodmeier Source Type: research
CircFOXN2 alleviates glucocorticoid- and tacrolimus-induced dyslipidemia by reducing FASN mRNA stability by binding to PTBP1 during liver transplantation
CONCLUSION: CircFOXN2 alleviated the dysregulation of lipid metabolism induced by the combination of TAC and Dex by modulating the PTBP1/FASN axis.PMID:37575056 | DOI:10.1152/ajpcell.00462.2022
Source: Am J Physiol Cell Ph... - August 14, 2023 Category: Cytology Authors: Li-Jian Chen Yang Xin Miao-Xian Yuan Chun-Yi Ji Yu-Ming Peng Qiang Yin Source Type: research
Direct drug milling in organic PLGA solution facilitates the encapsulation of nanosized drug into PLGA microparticles
The objective of this study was to prepare poly(lactide-co-glycolide) (PLGA) microparticles loaded with nanosized drug by combining non-aqueous wet bead milling and microencapsulation. 200 - 300 nm dexamethasone, hydrocortisone and dexamethasone sodium phosphate nanosuspensions were successfully prepared by wet bead milling the drug in dichloromethane using PLGA as a stabilizer. PLGA microparticles loaded with nanosized drugs were then prepared by a solid-in-oil-in-water (S/O/W) solvent evaporation method or solid-in-oil-in-oil (S/O/O) organic phase separation method. The microparticles were characterized by laser diffract...
Source: European Journal of Pharmaceutics and Biopharmaceutics - August 14, 2023 Category: Drugs & Pharmacology Authors: Chenghao Zhang Roland Bodmeier Source Type: research
CircFOXN2 alleviates glucocorticoid- and tacrolimus-induced dyslipidemia by reducing FASN mRNA stability by binding to PTBP1 during liver transplantation
CONCLUSION: CircFOXN2 alleviated the dysregulation of lipid metabolism induced by the combination of TAC and Dex by modulating the PTBP1/FASN axis.PMID:37575056 | DOI:10.1152/ajpcell.00462.2022
Source: Am J Physiol Cell Ph... - August 14, 2023 Category: Cytology Authors: Li-Jian Chen Yang Xin Miao-Xian Yuan Chun-Yi Ji Yu-Ming Peng Qiang Yin Source Type: research
Hemophagocytic lymphohistiocytosis as a rare complication of dengue haemorrhagic fever: a case report
ConclusionThis case emphasizes the need to consider HLH as a potential complication when persistent fever and cytopenias are present after recovering from dengue fever, particularly in patients with unusual clinical features like hepatosplenomegaly. Early recognition and prompt treatment with appropriate immunosuppressive therapy, such as intravenous dexamethasone, can lead to a successful response and good prognosis.
Source: Journal of Medical Case Reports - June 1, 2023 Category: General Medicine Source Type: research
