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Infectious Disease: Meningitis

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Total 837 results found since Jan 2013.

Fat enhanced leukocyte-platelet-rich fibrin versus fascia lata in endoscopic reconstruction of CSF leaks
ConclusionThe fat enhanced L-PRF membrane is a valid reliable option in repair of CSF leaks. The membrane is autologous, readily available, easily prepared, and has the advange of including stromal fat, stromal vascular fraction (SVF), and leukocyte-platelet-rich fibrin (L-PRF). The present study showed that fat enhanced L-PRF membrane is stable, non-absorbable, not liable to shrink or become necrotic, and can establish good seal of the skull base defect and further enhance the healing process. The use of the membrane also has the advantage of avoiding thigh incision and possible hematoma formation.
Source: European Archives of Oto-Rhino-Laryngology - August 21, 2023 Category: ENT & OMF Source Type: research

Reducing CSF complications by a recycled Hadad ’s flap combined with autologous mucosa in secondary endoscope transsphenoidal surgery
ConclusionA recycled HBF incorporated with an autologous mucosa is reliable for reconstructing the skull base in secondary transsphenoidal surgery, especially for patients simultaneously suffering from diabetes mellitus and central skull base tumors.
Source: Frontiers in Oncology - August 2, 2023 Category: Cancer & Oncology Source Type: research

Fat enhanced leukocyte-platelet-rich fibrin versus fascia lata in endoscopic reconstruction of CSF leaks
ConclusionThe fat enhanced L-PRF membrane is a valid reliable option in repair of CSF leaks. The membrane is autologous, readily available, easily prepared, and has the advange of including stromal fat, stromal vascular fraction (SVF), and leukocyte-platelet-rich fibrin (L-PRF). The present study showed that fat enhanced L-PRF membrane is stable, non-absorbable, not liable to shrink or become necrotic, and can establish good seal of the skull base defect and further enhance the healing process. The use of the membrane also has the advantage of avoiding thigh incision and possible hematoma formation.
Source: European Archives of Oto-Rhino-Laryngology - July 28, 2023 Category: ENT & OMF Source Type: research

Early Surgical Management of Displaced Orbital Roof Fractures: Prospective Observational Study
This study aimed to evaluate the clinical, radiological and functional outcome of early (within 24  h) surgical intervention of displaced orbital roof fractures. This is a prospective observational study for patients with displaced orbital roof fractures. Six patients underwent early surgical management within hours of admission. The primary outcome variables were functional and aesthetic (evalu ated through clinical and radiological assessments). The rate of immediate and delayed complications over a 6-months minimum follow-up period was recorded. All patients were males. The median age at the time of presentation was 23...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 22, 2023 Category: ENT & OMF Source Type: research

Rare Cases of Cerebrospinal Fluid Oto-Rhinorrhoea in Patients with Congenital Inner Ear Malformations
AbstractSpontaneous cerebrospinal fluid (CSF) oto-rhinorrhoea is rare and may develop secondary to inner ear malformation. Any child discharging watery fluid through nose or ear spontaneously in a head dependent position should be a high index of suspicion of CSF leak. If watery rhinorrhoea is present then apart from biochemical analysis of fluid discharge to confirm it to be CSF, computed tomography of paranasal sinuses and temporal bone should be carried out to differentiate between CSF oto-rhinorrhoea and CSF rhinorrhoea. Congenital deformities of the inner ear can be associated with meningitis and varying degrees of he...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 21, 2023 Category: ENT & OMF Source Type: research

Investigating the aggregation perspective of Dengue virus proteome
This study was designed to investigate, in detail, the predicted viral protein aggregation prone regions among all serotypes. Further, in order to understand the cross-talk between viral protein aggregation and aggregation of cellular proteins, cross-seeding experiments between the DENV NS1 (1-30), corresponding to the β-roll domain and the diabetes hallmark protein, amylin, were performed. Various techniques such as fluorescence spectroscopy, circular dichroism, atomic force microscopy and immunoblotting have been employed for this. We observe that the DENV proteomes have many predicted APRs and the NS1 (1-30) of DENV1-3...
Source: Virology - July 20, 2023 Category: Virology Authors: Shivani Krishna Kapuganti Kumar Udit Saumya Deepanshu Verma Rajanish Giri Source Type: research

A randomized trial of the effects of platelet- rich plasma on postoperative complications after meningomyelocele sac repair
CONCLUSIONS: We have shown that PRP treatment of postoperative meningomyelocele infants facilitates healing and lowers the risk of CSF leakage, meningitis, and skin necrosis.PMID:37401291 | DOI:10.26355/eurrev_202306_32792
Source: Pharmacological Reviews - July 4, 2023 Category: Drugs & Pharmacology Authors: Ö Arabacı M E Akyol E Çelikkaleli B S önmez E Çetin B Beger Source Type: research