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Nutrition: Sodium
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60% Of Sun Screens Would Fail Federal Safety Tests!
Here in South Florida, spring break is in full swing.
Temperatures are in the mid-to-high-80s, and tourists are flocking to our beautiful, sunny beaches.
Of course, that also means it’s prime time for sunscreen companies to kick up their marketing efforts in an attempt to whip up more fear over the sun.
They want to scare you into thinking that each time the sun strikes your unprotected skin, you risk malignant melanoma, the deadliest form of skin cancer.
If you’re a regular reader, you know that I’ve been vocal about Big Retail’s money grab and how they put out misinformation because they profit each time you slat...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Source Type: news
Molecules, Vol. 28, Pages 6685: Relation between Conventional and Starch-Assisted ASP Injection and Impact of Crystallinity on Flood Formation
This study explores conventional ASP flooding using PT SPR Langgak’s special surfactants, simulating Langgak oilfield conditions in Sumatra, Indonesia. By comparing the outcomes of this flooding technique with that of starch-assisted ASP performed in another study, the benefits of adding starch nanoparticles to flooding are evident. Nano-starch ASP increased oil recovery by 18.37%, 10.76%, and 10.37% for the three configurations investigated in this study. Water flooding preceded ASP flooding, and flooding operations were carried out at 60 °C. This study employed sodium hydroxide (NaOH), sodium ca...
Source: Molecules - September 18, 2023 Category: Chemistry Authors: Hasanain A. Al-Jaber Agus Arsad Sulalit Bandyopadhyay Mohd Zaidi Jaafar Muhammad Tahir Mustafa Jawad Nuhma Abdulmunem R. Abdulmunem Mohammad Yasin Abdulfatah Hajar Alias Tags: Article Source Type: research
Double layer spherical Nanoparticles with Hyaluronic Acid Coating to Enhance Oral Delivery of Exenatide in T2DM rats
Eur J Pharm Biopharm. 2023 Sep 6:S0939-6411(23)00236-9. doi: 10.1016/j.ejpb.2023.09.003. Online ahead of print.ABSTRACTSoybean phospholipid was used as an amphiphilic material to form reverse micelles (RMs) in medium glycerol monolinoleate (Maisine) with Exenatide (EXT.) encapsulated in the polar core formed by the hydrophilic part of phospholipid. Cremopher RH40 and caprylocaproyl macrogol-8 glycerides EP/caprylocaproyl polyoxyl-8 glycerides NF (Labrasol) were added as surfactants to prepare reverse micelle-self emulsifying drug delivery system (RMs-SEDDS). On this basis, oil in water (O/W) emulsion was further prepared. ...
Source: European Journal of Pharmaceutics and Biopharmaceutics - September 8, 2023 Category: Drugs & Pharmacology Authors: Yiying Lu Linjie Wu Mengting Lin Xiaoyan Bao Haiqing Zhong Peng Ke Qi Dai Qiyao Yang Xinjiang Tang WenHong Xu DongHang Xu Min Han Source Type: research
Characterization of airborne particulate matter and its toxic and proarrhythmic effects: A case study in Aburr á Valley, Colombia
This study characterized the PM collected from the north, south, and central zones to evaluate its chemical composition and morphology. Different elements such as silicon, carbon, aluminum, potassium, calcium, sodium, iron, magnesium, and copper and the presence of unburned fuel, motor oil, and silicon fibers were identified. In vitro and in silico studies were conducted to evaluate the toxicity of the PM, and it was found that the PM collected from the central zone had the greatest impact on cell viability and caused DNA damage. The in silico study demonstrated that PM has concentration-dependent proarrhythmic effects, re...
Source: Environmental Pollution - August 31, 2023 Category: Environmental Health Authors: Laura C Palacio Geraldine Durango-Giraldo Camilo Zapata-Hernandez Gloria A Santa-Gonz ález Diego Uribe Javier Saiz Robison Buitrago-Sierra Catalina Tob ón Source Type: research
Sesamin ameliorates lipotoxicity and lipid accumulation through the activation of the estrogen receptor alpha signaling pathway
This study aimed to explore the molecular mechanisms by which sesamin may improve lipid metabolism dysregulation. A in vitro hepatic steatosis model was established by exposing HepG2 cells to palmitate sodium. The results showed that sesamin effectively mitigated lipotoxicity and reduced reactive oxygen species production. Additionally, sesamin suppressed lipid accumulation by regulating key factors involved in lipogenesis and lipolysis, such as fatty acid synthase (FASN), sterol regulatory element-binding protein 1c (SREBP-1c), forkhead box protein O-1, and adipose triglyceride lipase. Molecular docking results indicated ...
Source: Biochemical Pharmacology - August 31, 2023 Category: Drugs & Pharmacology Authors: Thi Hoa Pham Gi Ho Lee Sun Woo Jin Seung Yeon Lee Eun Hee Han Nam Doo Kim Chul Yung Choi Gil-Saeng Jeong Sang Ki Lee Hyung Sik Kim Hye Gwang Jeong Source Type: research
Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition
ConclusionsAltered expression of CR-dependent regulatory genes during PNAC accompanies cholestasis and is, in part, due to increased cytokine (IL-1 β and TNFα) production. Evaluation of the effects of modulating CR in PNAC thus deserves further investigation.
Source: PLoS One - August 30, 2023 Category: Biomedical Science Authors: Colin T. Shearn Source Type: research
Colonization potential of endophytes from halophytic plants growing in the “Runn of Kutch” salt marshes and their contribution to mitigating salt stress in tomato cultivation
Increasing soil salinity depreciates the quantity of the crop produce. Looking at the tremendous potential of plant-associated microorganisms in salinity stress mitigation, it would be very useful in exploring and deciphering salt-tolerant microorganisms from halophytic plants and their utilization in cultivated plants. With this aim, in the present study, four halophytic plants were taken from Rann of Kutch, and bacterial endophytes were isolated from different plant organs. These endophytes were characterized by plant growth and health promotion features. The molecular identification was done based on 16 s rRNA sequenc...
Source: Frontiers in Microbiology - August 29, 2023 Category: Microbiology Source Type: research
An oral cholera vaccine in the prevention and/or treatment of inflammatory bowel disease
by Marine Meunier, Adrian Spillmann, Christel Rousseaux, Klaus Schwamborn, Melissa Hanson
The oral cholera vaccine WC-rBS consists of 4 different inactivated strains ofVibrio cholerae (LPS source) admixed with recombinant cholera toxin B subunit. Because of its unique composition and anti-inflammatory properties reported for both CTB and low doses of LPS from other Gram-negative bacteria, we speculated that WC-rBS might have anti-inflammatory potential in a chronic autoimmune disease such as inflammatory bowel diseases. Firstin vitro endotoxin tolerance experiments showed the surprising WC-rBS potential in the modulation ...
Source: PLoS One - August 28, 2023 Category: Biomedical Science Authors: Marine Meunier Source Type: research
New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN
Physiol Rev. 2023 Aug 24. doi: 10.1152/physrev.00014.2022. Online ahead of print.ABSTRACTCell excitability and its modulation by hormones and neurotransmitters involve the concerted action of membrane proteins, especially ion channels. Unique complements of co-expressed ion channels are exquisitely balanced against each other in different excitable cell types, establishing distinct electrical properties that are tailored for diverse physiological contributions, and dysfunction of any component may induce a disease state. A crucial parameter controlling cell excitability is the resting membrane potential (RMP) set by extra-...
Source: Physiological Reviews - August 24, 2023 Category: Physiology Authors: Arnaud Monteil Nathalie C Gu érineau Antonio Gil-Nagel Paloma Parra-Diaz Philippe Lory Adriano Senatore Source Type: research
