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Procedure: Heart Valve Surgery
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Total 1815 results found since Jan 2013.
Nephrotic syndrome induced by aortic regurgitation with Takayasu arteritis: an autopsy case with long-term clinical follow-up
AbstractTakayasu arteritis is a rare, chronic, and large-vessel vasculitis involving the aorta and its branches in a complex autoimmune reaction. Takayasu arteritis sometimes complicates aortic regurgitation and chronic kidney disease, but rarely accompanies nephrotic syndrome. We had a patient with Takayasu arteritis and concomitant aortic regurgitation. She had nephrotic syndrome that was refractory to immunosuppressive therapy but was promptly improved after surgical aortic valve replacement. In her kidney biopsy, glomeruli had mild mesangial proliferative changes without immune complex deposition. Her proteinuria remai...
Source: CEN Case Reports - September 22, 2023 Category: Urology & Nephrology Source Type: research
Minimally invasive, surgical, and transcatheter aortic valve replacement: Network meta-analysis
CONCLUSIONS: MS was protective against 30-day mortality, stroke, AKI, and long-term mortality compared to FS; TAVR showed higher rates of 30-day PVL and PPM but was protective against AKI. Conversely, MT showed higher rates of 30-day PVL and major bleeding. With the emergence of TAVR, the appropriate benchmarks for SAVR comparison in future trials should be the minimally-invasive SAVR approaches to provide clinical equipoise.PMID:37611742 | DOI:10.1016/j.jjcc.2023.08.010
Source: Journal of Cardiology - August 23, 2023 Category: Cardiology Authors: Ahmed K Awad Adham Ahmed Dave M Mathew Kathryn S Varghese Serena M Mathew Sofia Khaja Paige C Newell Alexis K Okoh Sameer Hirji Source Type: research
Cusp overlap technique decreases paravalvular leakage in self-expandable transcatheter aortic valve replacement
AbstractThe cusp overlap technique allows greater visual separation between the basal annular plane and the conduction system and decreases the permanent pacemaker implantation rate. We assessed the impact of the cusp overlap technique on conduction disturbance and paravalvular leakage after transcatheter aortic valve replacement. A total of 97 patients underwent transfemoral transcatheter aortic valve replacement with self-expandable valves at our institution from November 2018 to January 2023. The mean age of the patients was 85 years, and 23% were male. The patients were divided into two groups: the cusp overlap techn...
Source: Heart and Vessels - August 22, 2023 Category: Cardiology Source Type: research
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Transcatheter aortic valve replacement with the self-expanding ACURATE Neo2 in patients with horizontal aorta: Insights from the ITAL-neo registry
Horizontal aorta (HA), defined by an aortic angulation (AA) ≥48°, is associated with worse outcomes particularly after self-expanding (SE) trans-catheter heart valve (THV) implantation. Although the SE ACURATE Neo THV demonstrated favorable procedural success rates in patients with HA, it remains associated with a non-negligible rate of moderate or greate r paravalvular leak (PVL).
Source: International Journal of Cardiology - July 30, 2023 Category: Cardiology Authors: Monica Barki, Alfonso Ielasi, Andrea Buono, Diego Maffeo, Carolina Montonati, Dario Pellegrini, Mariano Pellicano, Riccardo Gorla, Giuliano Costa, Ottavia Cozzi, Marco Ancona, Francesco Soriano, Marco De Carlo, Erica Ferrara, Francesco Giannini, Mauro Mas Source Type: research
Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells.
Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Experimental observation on a new chimney-shaped mechanical valve completely implanted above the mitral annulus in animals
This study aims to perform the preclinical large animal experiments for surgically implanting a chimney-shaped artificial mechanical heart valve with zero left ventricular occupancy, which fully accommodates the movement of the valve leaflets in the valve frame and realizes completely supra-annular surgical implantation. A total of 7 sheep underwent the replacement of artificial valve, and 5 sheep survived normally until anatomical examination. The mechanical properties of these artificial mitral valves remain functionally normal. There was no obvious thromboembolism around the artificial valve and in the important organs....
Source: General Thoracic and Cardiovascular Surgery - July 15, 2023 Category: Cardiovascular & Thoracic Surgery Source Type: research
Comparison of hemodynamics and root configurations between remodeling and reimplantation methods for valve-sparing aortic root replacement: a pulsatile flow study
ConclusionsRM with ESA and RI with neo-sinuses showed comparable hemodynamics. ESA to RM reduced regurgitation.
Source: Surgery Today - June 26, 2023 Category: Surgery Source Type: research
1-year outcomes of patients implanted with the Perceval sutureless valve: the Japanese post-marketing surveillance study
AbstractSutureless offers an alternative to standard valves in surgical aortic valve replacement (SAVR). We sought to confirm the efficacy and safety of the Perceval sutureless valve in Japanese patients. Prospective observational study of 204 patients who underwent SAVR with Perceval at 19 sites in Japan between March and December 2019. The primary outcomes were 30-day mortality and postoperative complications; the secondary outcome was all-cause mortality at 1 year. Efficacy outcomes were changed in New York Heart Association (NYHA) class, pressure gradients, effective orifice area (EOA), EOA indexed to body surface area...
Source: Heart and Vessels - May 30, 2023 Category: Cardiology Source Type: research
Less Invasive Procedure for 'Leaky' Heart Valves Proves Successful
A large study finds the minimally invasive intervention known as TEER (transcatheter edge-to-edge repair) effective for fixing tears in heart valves.
Source: WebMD Health - May 24, 2023 Category: Consumer Health News Source Type: news
Risk evaluation of adverse aortic events in patients with non-circular aortic annulus after transcatheter aortic valve implantation: a numerical study
This study numerically investigated the distribution of four wall shear stress (WSS)-based indicators and three helicity-based indicators in eight patient-specific aortas with different annulus including circular, type I elliptical and type II elliptical shapes. Both elliptical annulus features can significantly enhance the intensity of the helicity (h2) in the ascending aorta (p < 0.001). However, for the type I elliptical annulus, the spiral flow structure was changed into low-velocity and disturbed flow pattern close to the inner side of the aortic arch. For the type II elliptical annulus, the spiral flow remained bu...
Source: Biomechanics and Modeling in Mechanobiology - May 8, 2023 Category: Biomedical Science Authors: Jun Wen Qi Gao Jingnan Chen Xinya Li Kaiyue Zhang Gang He Min Dai Pan Song Source Type: research
