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Total 40 results found since Jan 2013.

Direct and crowding-out effects of a Hepatitis B vaccination campaign
Econ Hum Biol. 2023 Jul 23;51:101279. doi: 10.1016/j.ehb.2023.101279. Online ahead of print.ABSTRACTWe evaluate the direct and spillover causal effects of a Hepatitis B (HB) vaccination campaign in French schools on the vaccination adherence of the targeted pupils. Using a regression discontinuity design, we show that this campaign created an exogenous shock on vaccination behavior, increasing the HB vaccination rate for children aged 11 and above. At the same time, we show a drop in the measles, mumps, and rubella (MMR) vaccination rate of the targeted pupils and an increase in the parental belief that measles is a benign...
Source: Economics and Human Biology - August 11, 2023 Category: Biology Authors: Cl émentine Garrouste Arthur Juet Anne-Laure Samson Source Type: research

The Head of the Global Vaccine Group Gavi Is Resigning. Here ’s What He Learned During the Pandemic
The COVID-19 pandemic was a crucible for the public health world, and perhaps none were tested more than Gavi, the global nonprofit that makes vaccines its business. Faced with ensuring that the COVID-19 vaccines reached as many people in the developing world as possible, the organization created a new entity, COVAX, that served as the conduit for purchasing and distributing vaccines for the lowest-resource countries in the world. Dr. Seth Berkley, who has headed the organization for years, is stepping down in August when his current term ends. In a conversation with TIME, Berkley reflects on his tenure and what he, Gavi, ...
Source: TIME: Health - July 24, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

The Head of the Global Vaccine Group Gavi Is Stepping Down. Here ’s What He Learned During the Pandemic
The COVID-19 pandemic was a crucible for the public health world, and perhaps none were tested more than Gavi, the global nonprofit that makes vaccines its business. Faced with ensuring that the COVID-19 vaccines reached as many people in the developing world as possible, the organization created a new entity, COVAX, that served as the conduit for purchasing and distributing vaccines for the lowest-resource countries in the world. Dr. Seth Berkley, who has headed the organization for years, is stepping down in August when his current term ends. In a conversation with TIME, Berkley reflects on his tenure and what he, Gavi, ...
Source: TIME: Health - July 24, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Is a ‘polyepidemic’ humanity’s next big threat? Childhood vaccine crusader shares concerns for future
By the start of 2011, the year epidemiologist Seth Berkley became CEO of Gavi, the Vaccine Alliance, the ambitious nonprofit had over its 11-year history supported the immunization of 288 million children in poor countries. But it also had a $3.7 billion funding gap between its plans and donor financial pledges. Making matters worse, an internal battle raged about how much it should invest in strengthening health systems versus more technological solutions, such as new or improved vaccines, favored by its main funder, the Bill & Melinda Gates Foundation. “It was a crisis,” Berkley says. Berkley plans to step d...
Source: ScienceNOW - July 20, 2023 Category: Science Source Type: news

TWiV 995: Viral origin stories
TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid. Click arrow to play Download TWiV 995 (74 MB .mp3, 123 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server • More evidence for SARS-CoV-2 s...
Source: This Week in Virology - MP3 Edition - March 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed. The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Science Snippet: Lipids in the Limelight
This study could inform the advancement of new antibiotics.Developing new imaging technologies to track lipid droplet formation and breakdown in cancer cells. Understanding this phenomenon could shed light on why lipid droplets accumulate in these cells, which could aid in creating new therapies. Learn about other scientific terms with the NIGMS glossary.
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - July 27, 2022 Category: Research Authors: Chrissa Chverchko Tags: Cells Chemistry, Biochemistry and Pharmacology Cellular Processes COVID-19 Medicines Science-snippet Source Type: blogs

Vaccines based on the replication-deficient simian adenoviral vector ChAdOx1: Standardized template with key considerations for a risk/benefit assessment
Vaccine. 2022 Jun 14:S0264-410X(22)00755-1. doi: 10.1016/j.vaccine.2022.06.008. Online ahead of print.ABSTRACTReplication-deficient adenoviral vectors have been under investigation as a platform technology for vaccine development for several years and have recently been successfully deployed as an effective COVID-19 counter measure. A replication-deficient adenoviral vector based on the simian adenovirus type Y25 and named ChAdOx1 has been evaluated in several clinical trials since 2012. The Brighton Collaboration Benefit-Risk Assessment of VAccines by TechnolOgy (BRAVATO) was formed to evaluate the safety and other key fe...
Source: Vaccine - June 17, 2022 Category: Allergy & Immunology Authors: Pedro M Folegatti Daniel Jenkin Susan Morris Sarah Gilbert Denny Kim James S Robertson Emily R Smith Emalee Martin Marc Gurwith Robert T Chen Benefit-Risk Assessment of VAccines by TechnolOgy Working Group BRAVATO, ex-V3SWG) Source Type: research

Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Evaluation of Immune and Vaccine Competence in Steroid-Sensitive Nephrotic Syndrome Pediatric Patients
In conclusion, SSNS children at disease onset pre-immunosuppressive therapy showed a competent immune and vaccine response against tetanus and HBV, which can be correctly evaluated by quantification of antigen-specific memory B cells rather than by measuring serum IgG levels. This approach allows early identification of the impairment of immune and vaccine competence, which may derive from protracted use of different immunosuppressive drugs during disease course.
Source: Frontiers in Immunology - March 12, 2021 Category: Allergy & Immunology Source Type: research

Fight Aging! Newsletter, November 23rd 2020
In conclusion, the study indicates that HBOT may induce significant senolytic effects that include significantly increasing telomere length and clearance of senescent cells in the aging populations. Data on the Prevalence of Liver Fibrosis in Middle Age https://www.fightaging.org/archives/2020/11/data-on-the-prevalence-of-liver-fibrosis-in-middle-age/ Fibrosis is a consequence of age-related disarray in tissue maintenance processes, leading to the deposition of scar-like collagen that disrupts tissue structure and function. It is an ultimately fatal issue for which there are only poor treatment options a...
Source: Fight Aging! - November 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Viruses, Vol. 11, Pages 627: Identification, Pathogenicity of Novel Fowl Adenovirus Serotype 4 SDJN0105 in Shandong, China and Immunoprotective Evaluation of the Newly Developed Inactivated Oil-emulsion FAdV-4 Vaccine
In this study, we isolated a novel FAdV-4 strain SDJN0105 from a broiler farm with HHS disease in Shandong Province. Pathogenicity was evaluated by the observation of clinical symptoms, necropsy changes, and pathological tissue sections after oral and intramuscular (IM) infection of Specific pathogen free (SPF) chickens. The chickens infected by IM injection all died within three days, and chickens infected via the oculonasal route died within five days post-infection (dpi). Histopathological examination revealed that the pathology was confined to heart, liver, spleen, lung, kidney, and particularly the liver. Irrespective...
Source: Viruses - July 7, 2019 Category: Virology Authors: Kai Meng Xiaoyuan Yuan Jiang Yu Yuxia Zhang Wu Ai Youling Wang Tags: Article Source Type: research

Household transmission and disease transmissibility of a large HAV outbreak in Lazio, Italy, 2016–2017
Publication date: Available online 13 June 2019Source: EpidemicsAuthor(s): Giorgio GuzzettaAbstractA major outbreak of Hepatitis A Virus (HAV) has swept through Europe between mid-2016 and 2017, mainly within the community of men who have sex with men (MSM). Over the same period, about 1,000 outbreak-related cases of acute Hepatitis A (AHA) were recorded in Lazio region, Italy.We calibrated a Bayesian model to reconstruct likely transmission events within all 44 households where multiple infections were recorded, representing a total of 103 cases from the HAV outbreak in Lazio. Based on information on the observed times of...
Source: Epidemics - June 15, 2019 Category: Epidemiology Source Type: research