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Vaccination: Bird Flu (H5N1 Avian Influenza) Vaccine

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Total 76 results found since Jan 2013.

Prediction of highly pathogenic avian influenza vaccine efficacy in chickens by comparison of in vitro and in vivo data: A meta-analysis and systematic review
Vaccine. 2023 Aug 1:S0264-410X(23)00922-2. doi: 10.1016/j.vaccine.2023.07.076. Online ahead of print.ABSTRACTVaccines for avian influenza (AI) can protect poultry against disease, mortality, and virus transmission. Numerous factors, including: vaccine platform, immunogenicity, and relatedness to the field strain, are known to be important to achieving optimal AI vaccine efficacy. To better understand how these factors contribute to vaccine protection, a systematic meta-analysis was conducted to evaluate efficacy data for vaccines in chickens challenged with highly pathogenic (HP) AI. Data from a total of 120 individual tri...
Source: Vaccine - August 3, 2023 Category: Allergy & Immunology Authors: Jongseo Mo Erica Spackman David E Swayne Source Type: research

The U.S. Scientist At the Heart of COVID-19 Lab Leak Conspiracies Is Still Trying to Save the World From the Next Pandemic
Ralph Baric stepped onto the auditorium stage at the University of North Carolina, Chapel Hill, and looked out at the sparse audience that had come to hear him speak. On the large projector screen hanging behind him, the following words appeared: How Bad the Next Pandemic Could Be, What Might It Look Like, and Will We be Ready. The date was May 29, 2018. “Well, I have to admit I’m a little worried about giving this talk,” Baric said. “The reason is being labelled a harbinger of doom.” The screen shifted, and images of the four horsemen of the apocalypse—Death, Famine, War, and Plague&mda...
Source: TIME: Health - July 11, 2023 Category: Consumer Health News Authors: Dan Werb Tags: Uncategorized COVID-19 feature freelance Source Type: news

The ‘invented persona’ behind a key pandemic database
When Jeremy Kamil started to sequence samples of the rapidly spreading pandemic coronavirus in the spring of 2020, it was clear where he should deposit the genetic data: in GISAID , a long-running database for influenza genomes that had established itself as the go-to repository for SARS-CoV-2 as well. Kamil, a virologist at Louisiana State University’s (LSU’s) Health Sciences Center Shreveport, says he quickly struck up a friendly relationship with a Steven Meyers, who used a gisaid.org email address. The two often exchanged emails and talked on the phone, sometimes for hours, about the pandemic and data sh...
Source: ScienceNOW - April 19, 2023 Category: Science Source Type: news

Bird shots: Is vaccinating poultry the best defense against a deadly bird flu?
Lakeside, California— Hilliker’s Ranch Fresh Eggs in this San Diego suburb has 30,000 chickens in three “cage-free,” open-air barns, where birds crowd the floor like rush-hour riders on a big city subway. “A cage-free aviary is a very interesting science experiment,” says Frank Hilliker, who runs the farm his grandfather started in 1942. He worries mightily about infections spreading through the massed birds. On his iPhone, he pulls up a list of the vaccines his chickens get: against Newcastle disease, infectious laryngotracheitis, coryza, colibacillosis, salmonella, infectious bronchitis, and fowlpox....
Source: ScienceNOW - April 6, 2023 Category: Science Source Type: news

Live recombinant Newcastle disease virus vectored vaccine expressing the haemagglutinin of H9N2 avian influenza virus suppresses viral replication in chickens
In this study, rK148/Y280-HA, a novel recombinant Newcastle disease virus (NDV) vectored vaccine against Y280 lineage H9N2 LPAI was developed and evaluated using two mass-applicable administration methods, spray vaccination and drinking water vaccination. Regardless of low serum antibody haemagglutination inhibition titres against NDV and Y280 lineage H9N2 LPAI after applying the rK148/Y280-HA vaccine, vaccination with both administration methods protected chickens against virulent NDV and Y280-lineage H9N2 LPAIV after the challenge. Taken together, these results indicate that the rK148/Y280 vaccine can be administered usi...
Source: Avian Pathology - November 15, 2022 Category: Pathology Authors: Jiho Lee Andrew Y Cho Deok-Hwan Kim Joong-Bok Lee Seung-Yong Park In-Soo Choi Sang-Won Lee Chang-Seon Song Source Type: research

U.S. weighs crackdown on experiments that could make viruses more dangerous
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Source: ScienceNOW - October 19, 2022 Category: Science Source Type: news

Epidemiology and molecular characterization of avian influenza virus in backyard poultry of Chattogram, Bangladesh
Infect Genet Evol. 2022 Oct 8:105377. doi: 10.1016/j.meegid.2022.105377. Online ahead of print.ABSTRACTDucks, the natural reservoir of avian influenza virus (AIV), act as reassortment vessels for HPAI and low pathogenic avian influenza (LPAI) virus for domestic and wild bird species. In Bangladesh, earlier research was mainly focused on AIV in commercial poultry and live bird markets, where there is scanty literature reported on AIV in apparently healthy backyard poultry at the household level. The present cross-sectional study was carried out to reveal the genomic epidemiology of AIV of backyard poultry in coastal (Anowar...
Source: Infection, Genetics and Evolution - October 11, 2022 Category: Genetics & Stem Cells Authors: Pronesh Dutta Ariful Islam Md Abu Sayeed Md Ashiqur Rahman Md Sadeque Abdullah Otun Saha Mohammed Ziaur Rahman Marcel Klaassen Md Ahasanul Hoque Mohammad Mahmudul Hassan Source Type: research

Using social contact data to improve the overall effect estimate of a cluster-randomized influenza vaccination program in Senegal
This study estimates the overall effect of two influenza vaccination programs consecutively administered in a cluster-randomized trial in western Senegal over the course of two influenza seasons from 2009-2011. We apply cutting-edge methodology combining social contact data with infection data to reduce bias in estimation arising from contamination between clusters. Our time-varying estimates reveal a reduction in seasonal influenza from the intervention and a nonsignificant increase in H1N1 pandemic influenza. We estimate an additive change in overall cumulative incidence (which was 6.13% in the control arm) of -0.68 perc...
Source: Cancer Control - June 20, 2022 Category: Cancer & Oncology Authors: Gail E Potter Nicole Bohme Carnegie Jonathan D Sugimoto Aldiouma Diallo John C Victor Kathleen M Neuzil M Elizabeth Halloran Source Type: research