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Total 2475 results found since Jan 2013.
Pain-related stigma in patients with breast, colon, prostate or lung cancer : Results of a bicentric register-based cross-sectional study
CONCLUSIONS: Our findings support the assumption that the experience of pain can have an impact on the perceived stigmatization of cancer patients. Depression might influence the perceived stigmatization. Therefore, this group of patients should receive special attention and psycho-oncological care in clinical practice. Further research on the course and mechanisms of action of pain-related perceived stigmatization is also required.PMID:37710022 | DOI:10.1007/s00482-023-00752-3
Source: Schmerz - September 14, 2023 Category: Anesthesiology Authors: A Roicke P Esser B Hornemann J Ernst Source Type: research
Comorbidity in patients with Lichen sclerosus: a retrospective cohort study
This study confirmed the association between LS and vulvar cancer (OR = 17.4; 95% CI 12.1-25.3), penis cancer (OR = 9.1; 95% CI 4.3-18.9), prostate cancer (OR = 2.0; 95% CI 1.6-2.4) and breast cancer (OR = 1.6; 95% CI 1.4-1.8). LS was also associated with Crohn´s disease (OR = 2.0; 95% CI 1.6-2.6) and diabetes mellitus type 1 (OR = 1.9; 95% CI 1.6-2.1). The present study revealed novel important data regarding the association of LS with cancer and autoimmune diseases, emphasising the importance of sufficient treatment and follow-up of patients with LS. However, future studies are needed to confirm these results and the po...
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Sandra Jerkovic Gulin Filippa Lundin Oliver Seifert Source Type: research
Expression of microRNA-379 reduces metastatic spread of prostate cancer
DiscussionTaken together, our in vitro and in vivo functional assays support a role for miR-379 as a tumour suppressor. A potential mechanism is unravelled whereby miR-379 deregulation in PCa cells affects the secretion of GDF-15 from osteoblasts which in turn facilitates the metastatic establishment in bone. Our findings support the potential role of miR-379 as a therapeutic solution for prostate cancer.
Source: Frontiers in Oncology - September 12, 2023 Category: Cancer & Oncology Source Type: research
Comorbidity in patients with Lichen sclerosus: a retrospective cohort study
This study confirmed the association between LS and vulvar cancer (OR = 17.4; 95% CI 12.1–25.3), penis cancer (OR = 9.1; 95% CI 4.3–18.9), prostate cancer (OR = 2.0; 95% CI 1.6–2.4) and breast cancer (OR = 1.6; 95% CI 1.4–1.8). LS was also associated with Crohn´s disease (OR = 2.0; 95% CI 1.6–2.6) and diabetes mellitus type 1 (OR = 1.9; 95% CI 1.6–2.1). The present study revealed novel important data regarding the association of LS with cancer and autoimmune diseases, emphasising the importance of sufficient t reatment and follow-up of patients with LS. However, future studies are neede...
Source: European Journal of Medical Research - September 11, 2023 Category: Research Source Type: research
Androgen deprivation therapy caused a drastic proliferation of B-cell lymphoma with IgG4-related disease in patients with prostate cancer: a case report
CONCLUSION: This case is the first report of clinical significance regarding the crucial role of estrogen and estrogen receptor β in malignant lymphoma in a patient with IgG4-related disease. Our report aims to raise awareness of the need to carefully select treatment options for prostate cancer patients with IgG4-related disease or lymphoma.PMID:37688628 | DOI:10.1007/s00432-023-05292-y
Source: Cell Research - September 9, 2023 Category: Cytology Authors: Hajime Sasagawa Kazuyuki Numakura Mizuki Mori Mizuki Kobayashi Soki Kashima Ryohei Yamamoto Taketoshi Nara Mitsuru Saito Shintaro Narita Hiroshi Nanjo Tomonori Habuchi Source Type: research
SpaceOAR hydrogel distribution and early complications in patients undergoing radiation therapy for prostate cancer
CONCLUSIONS: Transperineal hydrogel placement separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy with a low rate of rectal wall injection and immediate complications.ADVANCES IN KNOWLEDGE: SpaceOAR hydrogel can be safely injected into radiation naive patients with low or intermediate-risk organ-confined prostate cancer. The spacer separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy.PMID:37660394 | DOI:10.1259/bjr.20220947
Source: The British Journal of Radiology - September 3, 2023 Category: Radiology Authors: Andrew H Yates Jack W Power Philip J Dempsey Adam Agnew Brian D Murphy Richard Moore Mazen El Bassiouni Michelle M J McNicholas Source Type: research
Pain Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with 223Ra: PARABO, a Prospective, Noninterventional Study
Conclusion: 223Ra reduced pain in patients with mCRPC and symptomatic bone metastases, particularly in patients who received 5–6 injections. The extent of metastatic disease did not impact pain response.
Source: Journal of Nuclear Medicine - September 1, 2023 Category: Nuclear Medicine Authors: Palmedo, H., Ahmadzadehfar, H., Eschmann, S., Niesen, A., Schonberger, J., Barsegian, V., Liepe, K., Mottaghy, F. M., Guan, R., Pinkert, J., Sandstrom, P., Herrmann, K. Tags: Clinical Investigations Source Type: research
CT-guided Transgluteal Prostate Fiducial Marker Insertion for Localized Radiation Therapy
ConclusionTransgluteal CT-guided fiducial marker implantation into the prostate is an alternative method to transperineal and transrectal approaches. In this technique, the risk of septic complications is minor, and general anesthesia is not required. Thus, transgluteal CT-guided marker insertion is a feasible and well-tolerated method for image-guided radiation therapy (IGRT) in patients with prostate cancer.
Source: CardioVascular and Interventional Radiology - August 28, 2023 Category: Radiology Source Type: research
Ultrasound Guided, Freehand Transperineal Prostate Biopsy: An Alternative to the Transrectal Approach
CONCLUSIONS: The use of ultrasound guided freehand transperineal prostate biopsy for the suspicion or surveillance of prostate cancer is feasible and safe. The results were encouraging with respect to the primary outcome measurements. Ultrasound guided freehand transperineal prostate biopsy with the patient under local anesthesia is currently under investigation. Large, prospective, randomized, multiple operator studies to evaluate the comparative effectiveness of freehand transperineal prostate biopsy and transrectal ultrasound guided biopsy techniques are recommended.PMID:37592459 | DOI:10.1016/j.urpr.2015.05.007
Source: Pain Physician - August 18, 2023 Category: Anesthesiology Authors: John Michael DiBianco Jeffrey K Mullins Matthew Allaway Source Type: research
Metastatic Prostate Adenocarcinoma Masquerading as Invasive Fungal Sinusitis
Ear Nose Throat J. 2023 Jul 28:1455613231189137. doi: 10.1177/01455613231189137. Online ahead of print.ABSTRACTA 58 year old male with a history of prostate adenocarcinoma presented with diplopia, severe headaches, and eye pain, consistent with sinusitis. Imaging was concerning for invasive fungal sinusitis (IFS) and an urgent ENT consultation was requested. Endoscopic sinus surgery was performed revealing metastatic prostate adenocarcinoma to the sinuses and anterior cranial fossa. The distinctive imaging features in this case are very useful when considering the divergent management options of IFS and metastatic sinus di...
Source: Ear, Nose and Throat Journal - July 29, 2023 Category: ENT & OMF Authors: Stephanie Huynh E Bradley Strong Osama Raslan Randall A Ow Source Type: research
