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Total 4011 results found since Jan 2013.

Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis
In conclusion, vutrisiran is an efficacious and generally well-tolerated alternative option for the treatment of polyneuropathy of hATTR amyloidosis, which has the potential advantage of infrequent subcutaneous dosage.
Source: Drugs - September 20, 2023 Category: Drugs & Pharmacology Source Type: research

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Managing osteoporosis in COPD
Endocr Metab Immune Disord Drug Targets. 2023 Sep 13. doi: 10.2174/1871530323666230913105752. Online ahead of print.ABSTRACTChronic obstructive pulmonary disease (COPD) is a serious respiratory disease with high morbidity, disability and mortality worldwide. Every year, many people die from the disease or its comorbidities. Osteoporosis is a common complication of COPD, which can lead to increased fractures in COPD patients, aggravate the disease, and then bring great pain and burden to patients. The possible factors leading to osteoporosis in COPD patients include systemic inflammation, corticosteroid use, vitamin D defic...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Drugs & Pharmacology Authors: Lilan Shen Juanqin Lv Jie Li Jing Zhou Xiaomin Wang Source Type: research

The effect of vitamin D treatment on quality of life in patients with fibromyalgia
ConclusionWe determined that vitamin D deficiency is significantly more prevalent in patients diagnosed with fibromyalgia. Vitamin D supplementation was observed to have a positive effect on quality of life and reduction of pain.
Source: Irish Journal of Medical Science - September 14, 2023 Category: General Medicine Source Type: research

Novel Variant of < em > SLC34A3 < /em > in a Compound Heterozygous Brazilian Girl with Hereditary Hypophosphatemic Rickets with Hypercalciuria
We report a Brazilian girl with HHRH who presented with knee pain and progressive genu valgum deformity that became apparent later in childhood (at age 8). Nephrocalcinosis was also identified at age 13. Next-generation sequencing (NGS) target panel directed to inherited forms of rickets detected compound heterozygous pathogenic variants in SLC34A3, including a novel missense variant c.1217G>T (p.Gly406Val). Compliance to oral phosphorus therapy was suboptimal and adjunctive chlorthalidone therapy improved hypercalciuria. Our case highlights the phenotypic variability of patients with HHRH and expands the growing list o...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - September 8, 2023 Category: Endocrinology Authors: Luciana Pinto Valadares Daniel Rocha de Carvalho Source Type: research