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Total 71574 results found since Jan 2013.

Nose-to-Brain Delivery of Hesperidin Nanoparticles Loaded In-Situ Gel for Neuroprotective Action
CONCLUSION: This study showed the potential of HSP NPs to be an effective neuroprotective agent.PMID:37708993 | DOI:10.1016/j.pharma.2023.09.001
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Suraj Bamankar Vaishali Londhe Source Type: research

Nose-to-brain delivery of hesperidin nanoparticles loaded in-situ gel for neuroprotective action
CONCLUSION: This study showed the potential of HSP NPs to be an effective neuroprotective agent.PMID:37708993 | DOI:10.1016/j.pharma.2023.09.001
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Suraj Bamankar Vaishali Londhe Source Type: research

Nose-to-Brain Delivery of Hesperidin Nanoparticles Loaded In-Situ Gel for Neuroprotective Action
CONCLUSION: This study showed the potential of HSP NPs to be an effective neuroprotective agent.PMID:37708993 | DOI:10.1016/j.pharma.2023.09.001
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Suraj Bamankar Vaishali Londhe Source Type: research

PLGA-based microspheres loaded with metformin hydrochloride: modified double emulsion method preparation, optimization, characterization, and in vitro evaluation
Ann Pharm Fr. 2023 Sep 12:S0003-4509(23)00105-0. doi: 10.1016/j.pharma.2023.09.002. Online ahead of print.ABSTRACTThe modified solvent removal method was used to encapsulate metformin hydrochloride (MH) within poly(lactic-co-glycolic acid) (PLGA) microspheres. The study investigated the effect of varying polymer concentrations on the loading and release of the drug from the microspheres. The encapsulation process involved using a double emulsion method, resulting in microspheres with particle diameters ranging from approximately 4.4 µm to 2.7 µm. The study achieved high encapsulation efficiencies, ranging from 81% to 90%...
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Priyanka Chauhan Himanshu Paliwal Chetan Singh Chauhan Ankit Paliwal Source Type: research

Charge variants of proposed biosimilar to Omalizumab: Isolation, purification and analysis by HPLC methods
In this study, biosimilar product of Xolair was expressed in mammalian cell culture process in laboratory to isolate charge variants (acidic, main peak and basic). Different charge variants were isolated from intermediate purified biosimilar product of Xolair. Isolated charge variants were purified with preparative cation exchange chromatography technique and characterized with different analytical tools includes size exclusion chromatography (SEC-HPLC) and cation exchange chromatography (CEX-HPLC). Purity of acidic, main peak and basic variants was 99.58%, 99.98% and 98.64% respectively as per SEC-HPLC and according to CE...
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Tarun Gupta Sriram Seshadri Source Type: research

Nose-to-Brain Delivery of Hesperidin Nanoparticles Loaded In-Situ Gel for Neuroprotective Action
CONCLUSION: This study showed the potential of HSP NPs to be an effective neuroprotective agent.PMID:37708993 | DOI:10.1016/j.pharma.2023.09.001
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Suraj Bamankar Vaishali Londhe Source Type: research

PLGA-based microspheres loaded with metformin hydrochloride: modified double emulsion method preparation, optimization, characterization, and in vitro evaluation
Ann Pharm Fr. 2023 Sep 12:S0003-4509(23)00105-0. doi: 10.1016/j.pharma.2023.09.002. Online ahead of print.ABSTRACTThe modified solvent removal method was used to encapsulate metformin hydrochloride (MH) within poly(lactic-co-glycolic acid) (PLGA) microspheres. The study investigated the effect of varying polymer concentrations on the loading and release of the drug from the microspheres. The encapsulation process involved using a double emulsion method, resulting in microspheres with particle diameters ranging from approximately 4.4 µm to 2.7 µm. The study achieved high encapsulation efficiencies, ranging from 81% to 90%...
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Priyanka Chauhan Himanshu Paliwal Chetan Singh Chauhan Ankit Paliwal Source Type: research

Charge variants of proposed biosimilar to Omalizumab: Isolation, purification and analysis by HPLC methods
In this study, biosimilar product of Xolair was expressed in mammalian cell culture process in laboratory to isolate charge variants (acidic, main peak and basic). Different charge variants were isolated from intermediate purified biosimilar product of Xolair. Isolated charge variants were purified with preparative cation exchange chromatography technique and characterized with different analytical tools includes size exclusion chromatography (SEC-HPLC) and cation exchange chromatography (CEX-HPLC). Purity of acidic, main peak and basic variants was 99.58%, 99.98% and 98.64% respectively as per SEC-HPLC and according to CE...
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Tarun Gupta Sriram Seshadri Source Type: research

Japanese pharma Eisai forms digital dementia support biz
It will commence operations in 2024 by releasing a predictive algorithm for early dementia diagnosis.  
Source: mobihealthnews - September 14, 2023 Category: Information Technology Source Type: news

GSK and Save the Children renew award-winning partnership, with focus on & #039;zero dose & #039; children who have never received a vaccine
GSK and Save the Children have announced today that they are renewing their award-winning partnership for a further five years. GSK will invest £15 million in the partnership with Save the Children and they will work together to increase child vaccination rates, with a focus on reducing the number of 'zero dose' children in Ethiopia and Nigeria.
Source: World Pharma News - September 14, 2023 Category: Pharmaceuticals Tags: Featured GlaxoSmithKline Business and Industry Source Type: news

Improved Pharma expands laboratory space by 50% to accommodate recent growth in our research and development programs
New expansion includes a solid-state analytical laboratory, additional client sample storage areas, and office space WEST LAFAYETTE, Ind., Sept. 14, 2023 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce it has recently expanded into adjacent laboratory space in the Purdue Kurz...
Source: PRWeb: Medical Pharmaceuticals - September 14, 2023 Category: Pharmaceuticals Tags: CXP Source Type: news