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American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control
Conclusions Collectively, there is consistent, compelling evidence that physical activity plays a role in preventing many types of cancer and for improving longevity among cancer survivors, although the evidence related to higher risk of melanoma demonstrates the importance of sun safe practices while being physically active. Together, these findings underscore the importance of physical activity in cancer prevention and control. Fitness and public health professionals and health care providers worldwide are encouraged to spread the message to the general population and cancer survivors to be physically active as their a...
Source: Medicine and Science in Sports and Exercise - October 17, 2019 Category: Sports Medicine Tags: SPECIAL COMMUNICATIONS Source Type: research

UV protection for young athletes: using participatory program planning to develop a sports schools program
ConclusionsPPP process has greatly influenced concept and materials of CSSP for sports schools. Integration of future program participants has proven to be an important component in creating a fitting and feasible program. CSSP for sports schools is a program free of charge that enables sports schools to integrate UVP into their daily routine. It will be disseminated in cooperation withGerman Olympic Sports Confederation andGerman Cancer Aid in 2021.
Source: Environmental Health and Preventive Medicine - August 9, 2020 Category: Environmental Health Source Type: research

Development of a skin cancer prevention programm for outdoor athlets
Conclusions We were able to give another hint for the relation of skin cancer development and the higher increase in outdoor sportsmen. From these data we developed in the UIPM for the athletes a "skin tumor prevention program". With this program the individual risk and the individual damage is analysed based on the cumulative UV-Dose of training and competition. Athletes, trainers and officials should be more sensitized in skin cancer prevention.
Source: British Journal of Sports Medicine - January 31, 2017 Category: Sports Medicine Authors: Nachtigall, N. Tags: Monaco abstracts Source Type: research

The Relationship Between Cricket Participation, Health, and Wellbeing: A Systematic Scoping Review
Int J Sports Med DOI: 10.1055/a-1686-6632Summarising and synthesising the evidence on cricket health and wellbeing can help inform cricket stakeholders and navigate future research directions. The purpose of this study was to investigate the relationship between cricket participation, health and wellbeing at all ages and playing standards, and identify research gaps in the existing literature. A scoping review was performed from inception to March, 2020. Studies were included if they assessed a construct related to health and/or wellbeing in cricketers, available in English. 219 articles ...
Source: International Journal of Sports Medicine - November 3, 2021 Category: Sports Medicine Authors: Bullock, Garrett Scott Perera, Nirmala Murray, Andrew Orchard, John Arden, Nigel A. Filbay, Stephanie R. Tags: Review Source Type: research

Associations between cardiorespiratory fitness in youth and the incidence of site-specific cancer in men: a cohort study with register linkage
CONCLUSION: We report a number of protective associations between higher CRF in healthy young men and the subsequent hazard of site-specific cancers. These results have implications for public health policymaking, strengthening the incentive to promote health through improving CRF in youth.PMID:37582636 | DOI:10.1136/bjsports-2022-106617
Source: British Journal of Sports Medicine - August 15, 2023 Category: Sports Medicine Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Eblom-Bak Hans Georg Kuhn Lauren Lissner Maria Åberg Mats B örjesson Source Type: research

Health headlines: focusing on hospital safety, using zebrafish to understand cancer and fixing ACL tears with a sponge
Boston Children’s Hospital’s doctors and researchers are constantly working to uncover and understand health and medical questions. Health Headlines is a twice-monthly summary of some of the most important research findings and news. Top news this week includes how hospitals are changing to become safer, how zebrafish are helping cancer researchers make strides and how sponges are being used to repair torn ACLs. How hospitals are changing to become safer The New York Times “Opinionator” blog reports patient safety experts say that medical errors are more a function of faulty systems than faulty people. In recent ye...
Source: Thrive, Children's Hospital Boston - February 5, 2016 Category: Pediatrics Authors: Andrea Duggan Tags: Health Headlines In the News Research ACL reconstruction Division of Sports Medicine Leonard Zon Lyle Micheli Martha Murray Source Type: news

Bio Intelligence: 5 Ways the Age of Information Will Democratize Modern Medicine
On July 13th 2013 at 7:15 pm I was sitting in a Wegman’s café eating dinner with two startup founders I was mentoring when I received a phone call from a dermatologist. He had removed a mole from my 10-year-old daughter’s arm a week earlier. My daughter and my six-year-old son sat at the table next to us chatting, eating, and playing games on their tablets. With just three words –“This is bad”—our entire world changed. We never saw it coming, we had no information, we were immediately at the mercy of strangers, and the normal we had known was irrevocably shattered in an instant, never to return. Within two wee...
Source: Society for Participatory Medicine - July 31, 2016 Category: Journals (General) Authors: Nanette Mattox Tags: Book Review Source Type: news

In precision medicine, pioneering young patient teaches veteran doctor
Allison Schablein seems an unlikely candidate to teach medicine to Mark Kieran. She’s an 8-year-old New Hampshire second grader who loves basketball, hip hop, acrobatic dancing and jewelry. He’s a pediatric neuro-oncologist with a PhD in molecular biology, not to mention decades of clinical and research experience. But teach Kieran, Allison does. In December 2012, Allison was diagnosed with metastatic anaplastic astrocytoma brain tumors — two on her brain stem, two on her spine, and three at the top of her head. She had surgery and chemotherapy — and for two months her tumors responded to therapy. Then treatment st...
Source: Thrive, Children's Hospital Boston - January 28, 2016 Category: Pediatrics Authors: Irene Sege Tags: Diseases & Conditions Our Patients’ Stories Research Brain tumor Dana-Farber/Boston Children's Cancer and Blood Disorders Center glioma Mark Kieran precision medicine Source Type: news

117in * should personalised medicine be funded in countries with limited resources?
Personalised medicine implies that treatment is based on molecular analysis of an individual tumour specimen. A biomarker may define groups of patients who can benefit from a specific treatment, such as the Estrogen Receptor and HER2 in breast cancer, B-RAF mutation in melanoma and EGFR and ALK mutation in lung cancer. Large clinical trials support treatments based on these tests but whether they should be used in countries of limited resources depends on their cost-effectiveness compared to other potential use of limited resources for health-care. ER and tamoxifen and HER2 and trastuzumab as adjuvant therapy for breast ca...
Source: Annals of Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Tannock, I. F. Tags: ESMO Emerging Countries Committee (ECC) - AORTIC-SLACOM-UICC joint symposium: personalised medicine with limited resources: myth or reality? Source Type: research

Using Lessons From an Underserved Family Medicine Dermatology Fellowship to Improve Family Medicine Resident Learning in Dermatology (Richard Usatine MD)
The first half of the session will describe the only underserved family medicine dermatology fellowship in the country. The second half will apply ideas from the fellowship training to the training of family medicine residents in dermatology. One of the stated goals of the fellowship is to improve the quality of dermatology training across the board for family physicians. The faculty and fellows in the program have been instrumental in developing new resources and curricula in dermatology. These resources will be shared with the participants. Some of the special skills learned in the fellowship that could be taught to fami...
Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded - April 26, 2015 Category: Primary Care Source Type: news

Allison’ story: Precision medicine, hope and inspiration
  We are honored U.S. News & World Report has named Dana-Farber/Boston Children’s Cancer and Blood Disorders Center the #1 pediatric cancer program in the U.S. As we celebrate this honor, we’re reflecting on some of the greatest children’s stories ever told — stories of the patients and families whose lives touch ours and inspire us. Allison, a pediatric cancer survivor, is one of those patients. This hip-hop loving third grader is a pediatric brain tumor survivor and a precision medicine pioneer. Allison is examined by nurse Maryann Zimmerman. When Allison’s tumors stopped responding to ...
Source: Thrive, Children's Hospital Boston - June 30, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Dana-Farber/Boston Children's Cancer and Blood Disorders Center precision medicine Source Type: news

Allison ’ story: Precision medicine, hope and inspiration
  We are honored U.S. News & World Report has named Dana-Farber/Boston Children’s Cancer and Blood Disorders Center the #1 pediatric cancer program in the U.S. As we celebrate this honor, we’re reflecting on some of the greatest children’s stories ever told — stories of the patients and families whose lives touch ours and inspire us. Allison, a pediatric cancer survivor, is one of those patients. This hip-hop loving third grader is a pediatric brain tumor survivor and a precision medicine pioneer. Allison is examined by nurse Maryann Zimmerman. When Allison’s tumors stopped responding to ...
Source: Thrive, Children's Hospital Boston - June 30, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Dana-Farber/Boston Children's Cancer and Blood Disorders Center precision medicine Source Type: news

Prognostic Value of Functional Assessment of Cancer Therapy-General (FACT-G) in Advanced Non-Small-Cell Lung Cancer Treated with Korean Medicine.
Conclusion: The FACT-G total score and PWB score as HRQoL measurements were significant prognostic factors for survival in advanced NSCLC patients treated with Korean medicine. This finding implies that the FACT-G can be used in clinical practice as a predictor of survival in patients with advanced NSCLC. PMID: 32454853 [PubMed - as supplied by publisher]
Source: Evidence-based Complementary and Alternative Medicine - May 27, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Precision medicine and precision therapeutics: hedgehog signaling pathway, basal cell carcinoma and beyond.
Authors: Mohan SV, Chang AL Abstract Precision medicine and precision therapeutics is currently in its infancy with tremendous potential to improve patient care by better identifying individuals at risk for skin cancer and predict tumor responses to treatment. This review focuses on the Hedgehog signaling pathway, its critical role in the pathogenesis of basal cell carcinoma, and the emergence of targeted treatments for advanced basal cell carcinoma. Opportunities to utilize precision medicine are outlined, such as molecular profiling to predict basal cell carcinoma response to targeted therapy and to inform therap...
Source: Seminars in Cutaneous Medicine and Surgery - November 14, 2014 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research

The impact of companion diagnostic device measurement performance on clinical validation of personalized medicine
A key component of personalized medicine is companion diagnostics that measure biomarkers, for example, protein expression, gene amplification or specific mutations. Most of the recent attention concerning molecular cancer diagnostics has been focused on the biomarkers of response to therapy, such as V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations in metastatic colorectal cancer, epidermal growth factor receptor mutations in metastatic malignant melanoma. The presence or absence of these markers is directly linked to the response rates of particular targeted therapies with small‐molecule kinas...
Source: Statistics in Medicine - March 16, 2015 Category: Statistics Authors: Meijuan Li, Tinghui Yu, Yun‐Fu Hu Tags: Research Article Source Type: research