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Cancer: Squamous Cell Carcinoma

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Total 7262 results found since Jan 2013.

Prognostic Value of Functional Assessment of Cancer Therapy-General (FACT-G) in Advanced Non-Small-Cell Lung Cancer Treated with Korean Medicine.
Conclusion: The FACT-G total score and PWB score as HRQoL measurements were significant prognostic factors for survival in advanced NSCLC patients treated with Korean medicine. This finding implies that the FACT-G can be used in clinical practice as a predictor of survival in patients with advanced NSCLC. PMID: 32454853 [PubMed - as supplied by publisher]
Source: Evidence-based Complementary and Alternative Medicine - May 27, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Traditional Chinese medicine for oral squamous cell carcinoma: A Bayesian network meta-analysis protocol
Conclusions: The findings will provide reference for evaluating the efficacy and safety of different traditional Chinese medicine for OSCC, and provide a helpful evidence for clinicians to formulate the best adjuvant treatment strategy for OSCC patients. Trial registration number: INPLASY202090082.
Source: Medicine - October 23, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

The "other" types of skin cancer
Almost everyone knows about the dangers of melanoma, but there are also two lesser-known types of skin cancer: basal and squamous cell carcinoma. Lisa Garner, M.D., talks with "Sound Medicine" about their risks. Basal cell carcinoma is the most commonly diagnosed type of skin cancer. It occurs primarily in white or light-skinned people and frequently occurs in skin exposed to the sun, like the he....
Source: Sound Medicine - April 14, 2013 Category: Global & Universal Authors: Sound Medicine Source Type: news

Local Recurrence and Epithelial Dysplasia at the Resection Margin of Oral Squamous Cell Carcinoma
Objectives:  At the annual meeting of the American Academy of Oral Medicine (AAOM) in 2014, we reported on local recurrence resulting from dysplastic epithelia remaining at the resection margin in 15 patients with oral squamous cell carcinoma (OSCC). In the present study, the relationship between p53 status i n dysplasia at the resection margin and recurrence was investigated with the same series of 15 OSCCs.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - October 1, 2018 Category: ENT & OMF Authors: Ayaka Abe, Kenji Kawano Tags: Oral Medicine Source Type: research

Precision medicine for human cancers with Notch signaling dysregulation (Review).
Abstract NOTCH1, NOTCH2, NOTCH3 and NOTCH4 are transmembrane receptors that transduce juxtacrine signals of the delta‑like canonical Notch ligand (DLL)1, DLL3, DLL4, jagged canonical Notch ligand (JAG)1 and JAG2. Canonical Notch signaling activates the transcription of BMI1 proto‑oncogene polycomb ring finger, cyclin D1, CD44, cyclin dependent kinase inhibitor 1A, hes family bHLH transcription factor 1, hes related family bHLH transcription factor with YRPW motif 1, MYC, NOTCH3, RE1 silencing transcription factor and transcription factor 7 in a cellular context‑dependent manner, while non‑canonical Notch s...
Source: International Journal of Molecular Medicine - December 3, 2019 Category: Molecular Biology Authors: Katoh M, Katoh M Tags: Int J Mol Med Source Type: research

Eppikajutsuto (a Japanese herbal medicine) regulates mTOR and induces apoptosis in oral cancer cells
ConclusionsThe results suggested that eppikajutsuto might exhibit antitumor effect against OSC ‐19in vitro by suppressing mTOR activation. However, additional studiesin vitro andin vivo are required to confirm the antitumor effect of eppikajutsuto.
Source: Traditional and Kampo Medicine - April 20, 2020 Category: Complementary Medicine Authors: Haruna Makita, Kazuhira Endo, Akiko Shirai, Kanji Kawasaki, Rei Mishima, Yoshiya Kasahara, Kazuya Ishikawa, Takayoshi Ueno, Yosuke Nakanishi, Satoru Kondo, Naohiro Wakisaka, Tomokazu Yoshizaki, Keiko Ogawa ‐Ochiai Tags: ORIGINAL ARTICLE Source Type: research

miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer.
In conclusion, we report diagnostic miRNA biomarkers for in-depth clinical evaluation. Furthermore, in an effort to avoid unnecessary toxicity we propose predictive biomarkers. The biomarker candidates support personalized treatment decisions of lung cancer patients and await their confirmation in randomized clinical trials. PMID: 33253979 [PubMed - as supplied by publisher]
Source: Translational Research : the journal of laboratory and clinical medicine - November 27, 2020 Category: Laboratory Medicine Authors: Zhong S, Golpon H, Zardo P, Borlak J Tags: Transl Res Source Type: research

Nuclear Medicine Lymphoscintigraphy
Conclusions: NM imaging was negative in 3.3% and false positive in 0.67% of cases. No significant relationship between the lesion location and the tracer used to the results of NM LN mapping interpretation.
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Aboueldahab, N. Tags: Sarcoma/ Melanoma Source Type: research

Risk of obstructive sleep apnea after treatment of head and neck squamous cell carcinoma: a cross-sectional study
Journal of Clinical Sleep Medicine, Ahead of Print.
Source: Journal of Clinical Sleep Medicine : JCSM - March 3, 2022 Category: Sleep Medicine Authors: Ronald Gavidia Galit Levi Dunietz Louise M. O ’Brien Sonja G. Schütz Matthew E. Spector Paul L. Swiecicki Ronald D. Chervin 1Department of Neurology, Division of Sleep Medicine, University of Michigan, Ann Arbor, Michigan 2Department of Otolaryngology Source Type: research

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma.
Authors: Gong W, Xiao Y, Wei Z, Yuan Y, Qiu M, Sun C, Zeng X, Liang X, Feng M, Chen Q Abstract Precision medicine is a new strategy that aims at preventing and treating human diseases by focusing on individual variations in people's genes, environment and lifestyle. Precision medicine has been used for cancer diagnosis and treatment and shows evident clinical efficacy. Rapid developments in molecular biology, genetics and sequencing technologies, as well as computational technology, has enabled the establishment of "big data", such as the Human Genome Project, which provides a basis for precision medicine. Head and...
Source: Oncotarget - December 9, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The EANM practical guidelines for sentinel lymph node localisation in oral cavity squamous cell carcinoma
ConclusionThe present practice guidelines will help nuclear medicine practitioners play their essential role in providing high-quality lymphatic mapping for the care of early N0 oral cavity squamous cell carcinoma patients.
Source: European Journal of Nuclear Medicine and Molecular Imaging - January 29, 2019 Category: Nuclear Medicine Source Type: research

Current Trends in Precision Medicine and Next-Generation Sequencing in Head and Neck Cancer
Opinion statementAs the field of oncology enters the era of precision medicine and targeted therapies, we have come to realize that there may be no single “magic bullet” for patients with head and neck cancer. While immune check point inhibitors and some targeted therapeutics have shown great promise in improving oncologic outcomes, the current standard of care in most patients with head and neck squamous cell carcinoma (HNSCC) remains a combinati on of surgery, radiation, and/or cytotoxic chemotherapy. Nevertheless, advances in precision medicine, next-generation sequencing (NGS), and targeted therapies have a potenti...
Source: Current Treatment Options in Oncology - February 23, 2022 Category: Cancer & Oncology Source Type: research

Traditional Chinese medicine as complementary treatment for hepatocellular carcinoma
Conclusions: The prognostics and survival rate of patients with hepatocellular carcinomas may be enhanced by targeted treatment of this major cell population. Traditional Chinese medicine has shown benefits to both tumour progression and drug resistance, as well as to the prevention of recurrence and metastasis. [Ethiop. J. Health Dev. 2021; 35(4): 320-327]Key words: Hepatocellular carcinoma, Chinese medicine, herbal treatment, squamous cell carcinoma, cancer stem cells.
Source: Ethiopian Journal of Health Development - November 25, 2021 Category: African Health Authors: Jiao Kede, Bie Limei, Yin XiLing, Yu Liqiu Source Type: research

Rapid bone repair in a patient with lung cancer metastases to the spine using a novel herbal medicine: A case report.
Authors: Pu R, Zhao Q, Li Z, Zhang L, Luo X, Zeren Y, Yu C, Li X Abstract The prognosis of lung carcinoma with metastasis to the bone, particularly to the spine, is poor. Chemotherapy and radiotherapy are established treatments for metastatic bone disease, but their effectiveness is unsatisfactory and bone repair following their use is slow and difficult. Medicine prepared from herbal extracts may be an alternative treatment option. The present study discusses the case of a 59-year-old patient diagnosed with squamous cell lung cancer (T2N3M1) in which first-line chemotherapy using docetaxel plus cisplatin failed. H...
Source: Oncology Letters - September 8, 2016 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research