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Total 15396 results found since Jan 2013.

Understanding paraneoplastic syndromes in athletes.
Abstract The understanding of paraneoplastic syndromes has improved over the last several years. These disorders are brought about by tumor secretion of substances that can alter hormonal function and create immune cross-reactivity with normal tissues. This, in turn, can alter normal metabolic pathways resulting in paraneoplastic syndromes. The athlete must maintain an awareness of their body because these syndromes affect diverse organ systems. Commonly associated malignancies include small cell lung cancer, breast cancer, gynecologic tumors, and gastroenterological malignancies. These cancers most notably affect...
Source: Current Sports Medicine Reports - January 1, 2013 Category: Sports Medicine Authors: Cabry R, Ballyamanda S, Kraft M, Hong E Tags: Curr Sports Med Rep Source Type: research

Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk
CONCLUSION: The detrimental associations of poor sleep with all-cause and cause-specific mortality risks are exacerbated by low PA, suggesting likely synergistic effects. Our study supports the need to target both behaviours in research and clinical practice.PMID:34187783 | DOI:10.1136/bjsports-2021-104046
Source: British Journal of Sports Medicine - June 30, 2021 Category: Sports Medicine Authors: Bo-Huei Huang Mitch J Duncan Peter A Cistulli Natasha Nassar Mark Hamer Emmanuel Stamatakis Source Type: research

Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies
CONCLUSION: Muscle-strengthening activities were inversely associated with the risk of all-cause mortality and major non-communicable diseases including CVD, total cancer, diabetes and lung cancer; however, the influence of a higher volume of muscle-strengthening activities on all-cause mortality, CVD and total cancer is unclear when considering the observed J-shaped associations.SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020219808.PMID:35228201 | DOI:10.1136/bjsports-2021-105061
Source: British Journal of Sports Medicine - March 1, 2022 Category: Sports Medicine Authors: Haruki Momma Ryoko Kawakami Takanori Honda Susumu S Sawada Source Type: research

Stop hunting for zebras in Texas: end the diagnostic culture of "rule-out": We need to make the most of clinical context rather than order every investigation, writes Saurabh Jha
"The patient's skull was struck by a baseball bat. He has a perfectly legitimate reason for subarachnoid hemorrhage. He already had a CT [computed tomogram] of the head showing the bleed in good detail. Why another?" I remonstrated with Watson, the neurosurgeon. "But you don't know that there is no intracranial aneurysm. You can't rule that out. He needs a CT angiogram of the brain immediately," protested Watson. Hit by a hard object (cause) and blood in brain (effect) is deductive reasoning at its simplest. But Watson was correct: I could not rule out cerebral artery aneurysm without a CT angiogram. I could not, for that ...
Source: British Journal of Sports Medicine - October 30, 2015 Category: Sports Medicine Authors: Jha, S. Tags: Republished research from the BMJ Source Type: research

Alternative Medicine Alone Leads to Lower Cancer Survival
Cancer patients who opt for alternative therapy instead of conventional medicine significantly decrease their chances of survival, according to researchers at Yale School of Medicine. Although the popularity of alternative medicine continues to grow, a recent study published in the Journal of the National Cancer Institute found survival rates significantly reduced for those who use it as first-line therapy. Conventional cancer treatments — chemotherapy, surgery and radiation — still produce a much better chance of survival. Mesothelioma was not included in the study, but the findings are relevant to this rare and aggr...
Source: Asbestos and Mesothelioma News - August 23, 2017 Category: Environmental Health Authors: Matt Mauney Tags: acupuncture cancer Alternative medicine alternative mesothelioma treatment alternative therapy survival alternative vs conventional medicine breast cancer colon cancer Conventional cancer treatments Dr. David Gorski Dr. Skyler Johnson Source Type: news

Treatment of severe rash caused by crizotinib with both traditional Chinese medicine and Western medicine: Two case reports and literature review
Rationale: Lung adenocarcinoma is the most common pathologic pattern of lung cancer. During the past decades, a number of targeted agents have been explored to treat advanced lung adenocarcinoma. Recently, Crizotinib, the antagonist of anaplastic lymphoma kinase (ALK), has been widely used in ALK-rearranged lung cancer treatment. Crizotinib is generally well tolerated while its most frequent adverse events include visual disorders, gastrointestinal disturbances, cardiac and endocrine abnormalities. Rash caused by crizotinib is rarely seen, and there are few case reports of severe rash caused by crizotinib. Patient conce...
Source: Medicine - November 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Long-term use of combined conventional medicine and Chinese herbal medicine decreases the mortality risk of patients with lung cancer.
CONCLUSION: CHM users had significantly lower mortality than CHM nonusers. The longer the CHM use, the more the mortality HR declined. Glehnia littoralisF. Schmidt ex Miq., Polyporus umbellatus(Pers.) Fries and Trichosanthes kirilowii Maxim. possess a highly substantial anticancer activity compared with other herbs. PMID: 32951705 [PubMed - in process]
Source: Complementary Therapies in Medicine - July 31, 2020 Category: Complementary Medicine Authors: Yeh MH, Wu HC, Lin NW, Hsieh JJ, Yeh JW, Chiu HP, Wu MC, Tsai TY, Yeh CC, Li TM Tags: Complement Ther Med Source Type: research

Efficacy Analysis of Wandai Decoction Combined with Traditional Chinese Medicine Fumigation and Washing in Patients with Chronic Vaginitis After Sintilimab Treatment for Small Cell Lung Cancer
CONCLUSIONS: Wandai decoction combined with traditional Chinese medicine fumigation and washing was effective in treating chronic vaginitis after sintilimab treatment for small cell lung cancer. The treatment ameliorated symptoms of leukorrhea abnormalities, vulvar pruritus, and local inflammation, and promoted the recovery of the vaginal microbial environment. Despite the limitations of our study (small sample size and lack of comparison between different types of chronic vaginitis, which hinders the confirmation of extensive efficacy), we consider Wandai decoction combined with traditional Chinese medicine fumigation and...
Source: Alternative Therapies in Health and Medicine - June 15, 2023 Category: Complementary Medicine Authors: Yanjia Wu Lin Tang Source Type: research

117in * should personalised medicine be funded in countries with limited resources?
Personalised medicine implies that treatment is based on molecular analysis of an individual tumour specimen. A biomarker may define groups of patients who can benefit from a specific treatment, such as the Estrogen Receptor and HER2 in breast cancer, B-RAF mutation in melanoma and EGFR and ALK mutation in lung cancer. Large clinical trials support treatments based on these tests but whether they should be used in countries of limited resources depends on their cost-effectiveness compared to other potential use of limited resources for health-care. ER and tamoxifen and HER2 and trastuzumab as adjuvant therapy for breast ca...
Source: Annals of Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Tannock, I. F. Tags: ESMO Emerging Countries Committee (ECC) - AORTIC-SLACOM-UICC joint symposium: personalised medicine with limited resources: myth or reality? Source Type: research