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Cardiorespiratory fitness and death from cancer: a 42-year follow-up from the Copenhagen Male Study.
CONCLUSIONS: CRF is highly significantly inversely associated with death from cancer and all-cause mortality. The associations are robust for exclusion of subjects dying within 20 years of study inclusion, thereby suggesting a minimal influence of reverse causation.
PMID: 27888214 [PubMed - as supplied by publisher]
Source: British Journal of Sports Medicine - November 24, 2016 Category: Sports Medicine Authors: Jensen MT, Holtermann A, Bay H, Gyntelberg F Tags: Br J Sports Med Source Type: research
Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study.
CONCLUSIONS: Higher cardiorespiratory fitness was associated with lower risk of premature mortality and incidence of CVD, respiratory disease and colorectal cancer.
PMID: 30796106 [PubMed - as supplied by publisher]
Source: British Journal of Sports Medicine - February 22, 2019 Category: Sports Medicine Authors: Steell L, Ho FK, Sillars A, Petermann-Rocha F, Li H, Lyall DM, Iliodromiti S, Welsh P, Anderson J, MacKay DF, Pell JP, Sattar N, Gill JM, Gray SR, Celis-Morales CA Tags: Br J Sports Med Source Type: research
Physical Activity and Prostate Cancer: An Updated Review
AbstractProstate cancer affects a major proportion of older men, and effective preventive measures are few. Earlier suggestions of 10 –30% risk reduction from vigorous physical activity thus merit further analysis. This narrative review updates information on associations between physical activity and prostate cancer, seeking activity patterns associated with maximal risk reduction. Systematic searches of Ovid/MEDLINE and PubMed databases from 1996 to June 2016 have linked the terms prostate neoplasms/prostate cancer with occupation, occupational title, sedentary job or heavy work, exercise, physical activity, sports, at...
Source: Sports Medicine - November 13, 2016 Category: Sports Medicine Source Type: research
Associations between cardiorespiratory fitness in youth and the incidence of site-specific cancer in men: a cohort study with register linkage
CONCLUSION: We report a number of protective associations between higher CRF in healthy young men and the subsequent hazard of site-specific cancers. These results have implications for public health policymaking, strengthening the incentive to promote health through improving CRF in youth.PMID:37582636 | DOI:10.1136/bjsports-2022-106617
Source: British Journal of Sports Medicine - August 15, 2023 Category: Sports Medicine Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Eblom-Bak Hans Georg Kuhn Lauren Lissner Maria Åberg Mats B örjesson Source Type: research
Alternative Medicine Alone Leads to Lower Cancer Survival
Cancer patients who opt for alternative therapy instead of conventional medicine significantly decrease their chances of survival, according to researchers at Yale School of Medicine.
Although the popularity of alternative medicine continues to grow, a recent study published in the Journal of the National Cancer Institute found survival rates significantly reduced for those who use it as first-line therapy.
Conventional cancer treatments — chemotherapy, surgery and radiation — still produce a much better chance of survival.
Mesothelioma was not included in the study, but the findings are relevant to this rare and aggr...
Source: Asbestos and Mesothelioma News - August 23, 2017 Category: Environmental Health Authors: Matt Mauney Tags: acupuncture cancer Alternative medicine alternative mesothelioma treatment alternative therapy survival alternative vs conventional medicine breast cancer colon cancer Conventional cancer treatments Dr. David Gorski Dr. Skyler Johnson Source Type: news
Personalized medicine-based strategy for prostate cancer
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Akinobu Gotoh With the emergence of molecularly targeted drugs, the phrase “personalized medicine” has recently become frequently used in the medical community. This phrase basically refers to treatments based on the selection of optimum therapies for individual patients but it can also include treatments based on the integration of various new technologies to enhance clinical care. Interest in personalized medicine will likely continue to increase in the future. Given the rapid advances in molecular biology, genetic engineering, b...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Choosing Wisely® in Preventive Medicine
Publication date: Available online 5 May 2016 Source:American Journal of Preventive Medicine Author(s): Catherine J. Livingston, Randall J. Freeman, Amir Mohammad, Victoria C. Costales, Tisha M. Titus, Bart J. Harvey, Kevin M. Sherin The Choosing Wisely® initiative is a national campaign led by the American Board of Internal Medicine Foundation, focused on quality improvement and advancing a dialogue on avoiding wasteful or unnecessary medical tests, procedures, and treatments. The American College of Preventive Medicine (ACPM) Prevention Practice Committee is an active participant in the Choosing Wisely project....
Source: American Journal of Preventive Medicine - May 5, 2016 Category: Global & Universal Source Type: research
Traditional Chinese Medicine CFF ‐1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR‐related pathways in prostate cancer
In this study, we analyzed the effect of CFF‐1 (alcohol extract from an anticancer compound Chinese medicine) on prostate cancer (PCa) cell lines and studied in detail the mechanism of cell death induced by CFF‐1 in vitro and in vivo. From our data, we found for the first time that CFF‐1 obviously arrested cell cycle in G1 phase, decreased cell viability and then increased nuclear rupture in a dose‐dependent manner and finally resulted in apoptosis in prostate cancer cells. In molecular level, our data showed that CFF‐1 induced inhibition of EGFR auto‐phosphorylation and inactivation of EGFR. Disruption of EGFR...
Source: Cancer Medicine - March 13, 2018 Category: Cancer & Oncology Authors: Zhaomeng Wu, Qingyi Zhu, Yingying Yin, Dan Kang, Runyi Cao, Qian Tian, Yu Zhang, Shan Lu, Ping Liu Tags: Original Research Source Type: research
Nuclear medicine practice in Japan: a report of the eighth nationwide survey in 2017
ConclusionsSingle-photon examinations showed a continuous tendency toward a decline in the survey. In contrast, the number of hybrid SPECT/CT scanner examinations has increased. PET/CT study and radionuclide targeted therapy have steadily increased.
Source: Annals of Nuclear Medicine - June 23, 2019 Category: Nuclear Medicine Source Type: research
Radiation Exposure to the Nuclear Medicine personnel during preparation and handling of 213Bi- radiopharmaceuticals.
Conclusion: The study shows that the use of 213Bi-PSMA/DOTATOC for the therapy of CRPC and NET, respectively, has been convenient, safe and straightforward. The external radiation doses to the occupational workers involved in different procedures were far below the dose limits prescribed by the Regulatory Authority (20mSv/yr). The dose rates from the treated patients showed no detrimental effect on public and environment.
PMID: 31604889 [PubMed - as supplied by publisher]
Source: Journal of Nuclear Medicine Technology - October 13, 2019 Category: Nuclear Medicine Tags: J Nucl Med Technol Source Type: research
Theranostics: Leveraging Molecular Imaging and Therapy to Impact Patient Management and Secure the Future of Nuclear Medicine
This article provides an overview of already approved agents as well as those on the horizon. It is important that as these agents are clinically onboarded, nuclear medicine physicians have the expertise to deploy theranostics safely and efficiently, ensuring that these agents attain and maintain their position as leading lines of therapy in managing patients with cancer as well as becoming an important aspect of nuclear medicine practice in the future.
Source: Journal of Nuclear Medicine - March 1, 2020 Category: Nuclear Medicine Authors: Solnes, L. B., Werner, R. A., Jones, K. M., Sadaghiani, M. S., Bailey, C. R., Lapa, C., Pomper, M. G., Rowe, S. P. Tags: The State of the Art Source Type: research
39in * will circulating biomarkers help to deliver precision medicine?
Precision or personalised medicine represent an emerging approach in treating prostate cancer (PrCa) through the application of available technologies to identify molecular alterations that will allow us to tailor treatments to each particular case. Nonetheless, a preliminary critical step for the application of personalised medicine is to validate this approach through clinical trials that aim either to validate a predictive biomarker of response in a non–-selected population or to treat a selected population based on a strong biological rationale. A key handicap limiting the general implementation of this approach ...
Source: Annals of Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Olmos, D., Castro, E., Romero, N., Morales-Pancorbo, D. Tags: special symposium: precision medicine in prostate cancer Source Type: research
The International Society of Sexual Medicine's Process of Care for the Assessment and Management of Testosterone Deficiency in Adult Men
ConclusionDevelopment of a process of care is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to new insights into the pathophysiology of TD, as well as new, efficacious and safe treatments. We recommend that this process of care be re‐evaluated and updated by the ISSM in 4 years. Dean JD, McMahon CG, Guay AT, Morgentaler A, Althof SE, Becher EF, Bivalacqua TJ, Burnett AL, Buvat J, El Meliegy A, Hellstrom WJG, Jannini EA, Maggi M, McCullogh A, Torres LO and Zitzmann M. The International Society of Sexual Medicine's Process of care for...
Source: The Journal of Sexual Medicine - June 18, 2015 Category: Sexual Medicine Authors: John D. Dean, Chris G. McMahon, Andre T. Guay, Abraham Morgentaler, Stanley E. Althof, Edgardo F. Becher, Trinity J. Bivalacqua, Arthur L. Burnett, Jacques Buvat, Amr El Meliegy, Wayne J.G. Hellstrom, Emmanuele A Jannini, Mario Maggi, Andrew McCullogh, Lu Tags: Original Research Source Type: research
The International Society for Sexual Medicine's Process of Care for the Assessment and Management of Testosterone Deficiency in Adult Men
ConclusionDevelopment of a process of care is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to new insights into the pathophysiology of TD, as well as new, efficacious and safe treatments. We recommend that this process of care be re‐evaluated and updated by the ISSM in 4 years. Dean JD, McMahon CG, Guay AT, Morgentaler A, Althof SE, Becher EF, Bivalacqua TJ, Burnett AL, Buvat J, El Meliegy A, Hellstrom WJG, Jannini EA, Maggi M, McCullough A, Torres LO and Zitzmann M. The International Society for Sexual Medicine's Process of care f...
Source: The Journal of Sexual Medicine - July 1, 2015 Category: Sexual Medicine Authors: John D. Dean, Chris G. McMahon, Andre T. Guay, Abraham Morgentaler, Stanley E. Althof, Edgardo F. Becher, Trinity J. Bivalacqua, Arthur L. Burnett, Jacques Buvat, Amr El Meliegy, Wayne J.G. Hellstrom, Emmanuele A Jannini, Mario Maggi, Andrew McCullough, L Tags: Original Research Source Type: research
EGFR ‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer.
EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer.
Mol Med Rep. 2018 Mar 28;:
Authors: Wu Z, Zhu Q, Zhang Y, Yin Y, Kang D, Cao R, Tian Q, Lu S, Liu P
Abstract
Traditional Chinese medicine (TCM) has the synergistic effect of the combination of a single ingredient and a monomer, and systemic and local therapeutic effects in cancer treatment, through which TCM is able to enhance the curative effect and reduce the side effects. The present study analyzed the effect of TCM‑1 (an anti‑cancer TCM) on ...
Source: Molecular Medicine Reports - April 6, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research
