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Is previous history a reliable predictor for acute mountain sickness susceptibility? A meta-analysis of diagnostic accuracy.
CONCLUSIONS: The use of AMS history to guide prophylactic strategies for high-altitude ascent is not supported by the literature; however, the low sensitivity and specificity of this diagnostic test could reflect the quality of the available studies. Ensuring that the characteristics of the history and future ascents are similar may improve the clinical utility of AMS history.
PMID: 24297836 [PubMed - as supplied by publisher]
Source: British Journal of Sports Medicine - December 2, 2013 Category: Sports Medicine Authors: Macinnis MJ, Lohse KR, Strong JK, Koehle MS Tags: Br J Sports Med Source Type: research
Wilderness medicine at high altitude: recent developments in the field
Neeraj M Shah,1 Sidra Hussain,2 Mark Cooke,3 John P O’Hara,3 Adrian Mellor3,4 1Division of Asthma, Allergy and Lung Biology, King’s College London, UK; 2School of Medicine, University College London, London, UK; 3Research Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, UK; 4Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK Abstract: Travel to high altitude is increasingly popular. With this comes an increased incidence of high-altitude illness and therefore an increased need to improve our strategies to prevent a...
Source: Clinical Ophthalmology - September 24, 2015 Category: Opthalmology Tags: Open Access Journal of Sports Medicine Source Type: research
A Standardized Traditional Chinese Medicine Preparation Named Yejuhua Capsule Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Downregulating Toll-Like Receptor 4/Nuclear Factor-κB.
This study demonstrated that YJH exerted potential protective effects against LPS-induced ALI in mice and supported that YJH was a potential therapeutic drug for ALI in clinic. And its mechanisms were at least partially associated with downregulations of TLR4/NF-κB pathways.
PMID: 25878714 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - June 3, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Using standardized patients to evaluate medical students’ evidence‐based medicine skills
Conclusion: The EBM OSCE was successfully integrated into the existing eight‐station OSCE and was able to assess student EBM skills.This article is protected by copyright. All rights reserved
Source: Journal of Evidence-Based Medicine - November 1, 2015 Category: Journals (General) Authors: Richard Amini, Nicholas C Hernandez, Samuel M Keim, Paul R Gordon Tags: Original Article Source Type: research
A Review of Complementary and Alternative Medicine Therapies on Muscular Atrophy: A Literature Review of In Vivo/In Vitro Studies.
Conclusions: These results demonstrate that CAM could prevent muscular atrophy. Further studies about CAM on muscular atrophy are needed.
PMID: 30581489 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - December 26, 2018 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Comparison of Xilei-san, a Chinese Herbal Medicine, and Dexamethasone in Mild/Moderate Ulcerative Proctitis: A Double-Blind Randomized Clinical Trial
The Journal of Alternative and Complementary Medicine , Vol. 0, No. 0.
Source: The Journal of Alternative and Complementary Medicine - February 5, 2013 Category: Complementary Medicine Tags: article Source Type: research
The Time Course of Dexamethasone Delivery Using Iontophoresis Through Human Skin Measured via Microdialysis.
Conclusion Transdermal delivery of Dex-P during iontophoresis was successfully measured in vivo through human skin. Measureable concentrations of Dextotal were found regardless of current intensity. Although current induced vasodilation occurred, it did not significantly affect the tissue accumulation of Dextotal. J Orthop Sports Phys Ther, Epub 13 Feb 2015. doi:10.2519/jospt.2015.5308.
PMID: 25679344 [PubMed - as supplied by publisher]
Source: Physical Therapy - February 13, 2015 Category: Physiotherapy Authors: Rigby JH, Draper DO, Johnson AW, Myrer JW, Eggett DL, Mack GW Tags: J Orthop Sports Phys Ther Source Type: research
A knowledge translation initiative to enhance evidence-informed clinical management of achilles tendinopathy: the purpose, process and outcomes of the bc tendinopathy toolkit
Discussion
Clinicians want to provide evidence-informed management of tendinopathy but many struggle with accessing, appraising and synthesising the vast array of literature available on this topic. This KT initiative highlights the need for, challenges associated with, evidence-informed process for and positive response to the development of decision aids synthesising the current evidence to guide clinical management of this patient population.
Source: British Journal of Sports Medicine - May 10, 2013 Category: Sports Medicine Authors: Hoens, A. M., Ezzat, A., Anthony, J., Scott, A., Yates, M., Justesen, J. R., Hughes, D. Tags: Achilles tendinitis, Physiotherapy, Physiotherapy Abstracts from the 2nd International Scientific Tendinopathy Symposium (Vancouver, 2012) Source Type: research
Is previous history a reliable predictor for acute mountain sickness susceptibility? A meta-analysis of diagnostic accuracy
Conclusions
The use of AMS history to guide prophylactic strategies for high-altitude ascent is not supported by the literature; however, the low sensitivity and specificity of this diagnostic test could reflect the quality of the available studies. Ensuring that the characteristics of the history and future ascents are similar may improve the clinical utility of AMS history.
Source: British Journal of Sports Medicine - December 31, 2014 Category: Sports Medicine Authors: MacInnis, M. J., Lohse, K. R., Strong, J. K., Koehle, M. S. Tags: Mountain sickness Review Source Type: research
Doctors Say Trump ’ s Coronavirus Treatments Raise Questions
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 5, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Politics Syndicated CBSN Boston Syndicated Local Watch Listen Coronavirus Louisa Moller President Donald Trump Source Type: news
Ability to Suppress TGF- β-Activated Myofibroblast Differentiation Distinguishes the Anti-pulmonary Fibrosis Efficacy of Two Danshen-Containing Chinese Herbal Medicine Prescriptions
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD.
Introduction
Idiopathic pulmonary fibrosis (IPF) is a chronic ...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research
Application of Herbal Traditional Chinese Medicine in the Treatment of Acute Kidney Injury
Conclusion and Perspectives
Collectively, previous studies showed that numerous types of TCMs protect against AKI via different mechanisms of action, including inhibiting inflammation, cell apoptosis, necroptosis, ferroptosis, and restraining oxidative stress etc. These data support the potential application of these TCMs as novel therapeutic agents in treating patients with AKI. Although some TCMs have entered preclinical trials, it is essential to initiate pre-clinical pharmacologic and toxicologic trials and clinical trials to evaluate the efficacy and safety of TCMs usage. Moreover, considering that some TCMs are dele...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research
Effect of Antiasthma Simplified Herbal Medicine Intervention on neutrophil predominant airway inflammation in a ragweed sensitized murine asthma model.
CONCLUSION: ASHMI treatment was efficacious in a murine model of neutrophil-predominant asthma via modulation of innate chemokines, TH2 responses, nuclear factor-κB, and HDAC2. ASHMI, and/or its constituent GAC1, may be a valuable option for treating neutrophil-predominant asthma.
PMID: 24679734 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - April 1, 2014 Category: Allergy & Immunology Authors: Srivastava KD, Dunkin D, Liu C, Yang N, Miller RL, Sampson HA, Li XM Tags: Ann Allergy Asthma Immunol Source Type: research
Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats
Conclusion This result suggests antihypertensive effects of allicin in dexamethasone induced hypertension. However, further studies are needed to explore the detailed mechanism of antihypertensive effect of allicin.
Source: Integrative Medicine Research - April 11, 2017 Category: Complementary Medicine Source Type: research
Effects of intermittent pressure imitating rolling manipulation in traditional Chinese medicine on ultrastructure and metabolism in injured human skeletal muscle cells.
Conclusion: These results suggest that the mechanical effects of rolling manipulation in TCM could not only improve the recovery of injured skeletal muscle cells by ameliorating organelles arrangement, reducing organelle swelling, and maintaining nuclear membrane integrity, but also ameliorate the functions of cellular metabolism by increasing T-SOD activity and decreasing MDA content and CK activity in injured skeletal muscle. Then the Hippo/Yap signal pathway was detected, and the proteins in each group were detected by Western Blot. The protein expression of upstream protein p-LATS1 and downstream protein p-Yap (Ser127)...
Source: American Journal of Translational Research - February 15, 2020 Category: Research Tags: Am J Transl Res Source Type: research
