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Specialty: Laboratory Medicine

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Total 31064 results found since Jan 2013.

Laboratory and Sports medicine
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Volume: 55 Issue: s1 Pages: s805-s813
Source: Clinical Chemistry and Laboratory Medicine - May 22, 2017 Category: Laboratory Medicine Source Type: research

Precision Medicine in Gastrointestinal Pathology.
CONCLUSIONS: -Translating our ability to sequence thousands of genes into meaningful improvements in patient survival will be the challenge for the next decade. PMID: 27128302 [PubMed - as supplied by publisher]
Source: Archives of Pathology and Laboratory Medicine - April 30, 2016 Category: Laboratory Medicine Authors: Wang DH, Park JY Tags: Arch Pathol Lab Med Source Type: research

The Development and Implementation of a Novel Electronic Consult System by a Laboratory Medicine Service: Experience From the First 2 Years of Use.
CONCLUSIONS.—: This novel e-consult system improved accessibility to and documentation of answers to laboratory questions and increased the visibility of the pathology and laboratory medicine service. Future goals include development of outcomes-based measures to better assess the clinical impact of e-consults. PMID: 33367659 [PubMed - in process]
Source: Archives of Pathology and Laboratory Medicine - December 30, 2020 Category: Laboratory Medicine Authors: Stendahl K, Siddon AJ, Peaper DR, Hauser RG, Campbell S, Tormey CA Tags: Arch Pathol Lab Med Source Type: research

Translating the genetics of cystic fibrosis to personalized medicine.
Abstract Cystic fibrosis (CF) is the most common life-threatening recessive genetic disease in the Caucasian population. This multiorgan disease is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, a chloride channel recognized as regulating several apical ion channels. The gene mutations result either in the lack of the protein at the apical surface or in an improperly functioning protein. Morbidity and mortality because of the mutation of CFTR are mainly attributable to lung disease resulting from chronic infection/inflammation. Since its discovery as the causati...
Source: Translational Research : the journal of laboratory and clinical medicine - April 15, 2015 Category: Laboratory Medicine Authors: Corvol H, Thompson KE, Tabary O, le Rouzic P, Guillot L Tags: Transl Res Source Type: research

Pathology and Laboratory Medicine Support for the American Expeditionary Forces by the US Army Medical Corps During World War I.
Conclusions .- Both Siler and Wilson received Distinguished Service Medals. Wilson's vision for military pathology services helped transform American civilian laboratory services in the 1920s. PMID: 26317455 [PubMed - in process]
Source: Archives of Pathology and Laboratory Medicine - September 1, 2015 Category: Laboratory Medicine Authors: Wright JR, Baskin LB Tags: Arch Pathol Lab Med Source Type: research

A comprehensive, multidisciplinary, precision medicine approach to discover effective therapy for an undiagnosed, progressive, fibroinflammatory disease.
This report addresses the role of personalized medicine in identifying effective therapy for an undiagnosed disease. A 22-year-old woman presented with chronic severe recurrent trismus, facial pain, progressive multicentric inflammatory and fibrotic masses, and high C-reactive protein. Sites of disease included the pterygomaxillary region, masseter muscles, mandible, lung, pericardium, intrabdominal cavity, and retroperitoneum. A diagnosis was not established after an extensive assessment, including multiple biopsies. The patient was subsequently evaluated under the Undiagnosed Diseases Program at the National Institutes o...
Source: Translational Research : the journal of laboratory and clinical medicine - August 27, 2019 Category: Laboratory Medicine Authors: Gochuico BR, Ziegler SG, Ten NS, Balanda NJ, Mason CE, Zumbo P, Evans CA, Van Waes C, Gahl WA, Malicdan MCV Tags: Transl Res Source Type: research

Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015.
Authors: Ki CS, Lee H, Sung H, Kim S, Seong MW, Yong D, Kim JS, Lee MK, Kim MN, Choi JR, Kim JH, Korean Society for Laboratory Medicine MERS-CoV Laboratory Response Task Force Abstract For two months between May and July 2015, a nationwide outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) occurred in Korea. On June 3, 2015, the Korean Society for Laboratory Medicine (KSLM) launched a MERS-CoV Laboratory Response Task Force (LR-TF) to facilitate clinical laboratories to set up the diagnosis of MERS-CoV infection. Based on the WHO interim recommendations, the Centers for Disease Control and Preventi...
Source: Annals of Laboratory Medicine - February 29, 2016 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research

Concierge Medicine Increases in Popularity as More Consumers Opt for This Care Model; Will Clinical Laboratories Exploit This Business Opportunity?
Patients using a concierge medicine practice expect to pay cash at the time of service, but few medical laboratories are equipped to collect from patients at time of service One big challenge for clinical laboratories and anatomic pathology groups is how to adapt to the changing role of the consumer in healthcare. It a major […]
Source: Dark Daily - May 6, 2016 Category: Laboratory Medicine Authors: jude Tags: Laboratory Pathology AAMC AAPP Affordable Care Act American Academy of Private Physicians Association of American Medical Colleges boutique medicine clinical laboratory concierge medicine Concierge Medicine Today Dark Daily Dark Repo Source Type: news

Fundamentals of Pharmacogenetics in Personalized, Precision Medicine
This article introduces fundamental principles of pharmacogenetics as applied to personalized and precision medicine. Pharmacogenetics establishes relationships between pharmacology and genetics by connecting phenotypes and genotypes in predicting the response of therapeutics in individual patients. We describe differences between precision and personalized medicine and relate principles of pharmacokinetics and pharmacodynamics to applications in laboratory medicine. We also review basic principles of pharmacogenetics, including its evolution, how it enables the practice of personalized therapeutics, and the role of the cl...
Source: Clinics in Laboratory Medicine - July 2, 2016 Category: Laboratory Medicine Authors: Roland Valdes, DeLu (Tyler) Yin Source Type: research

The Future of Precision Medicine in Oncology
Precision medicine in oncology focuses on identifying which therapies are most effective for each patient based on genetic characterization of the cancer. Traditional chemotherapy is cytotoxic and destroys all cells that are rapidly dividing. The foundation of precision medicine is targeted therapies and selecting patients who will benefit most from these therapies. One of the newest aspects of precision medicine is liquid biopsy. A liquid biopsy includes analysis of circulating tumor cells, cell-free nucleic acid, or exosomes obtained from a peripheral blood draw. These can be studied individually or in combination and co...
Source: Clinics in Laboratory Medicine - August 9, 2016 Category: Laboratory Medicine Authors: Lori M. Millner, Lindsay N. Strotman Source Type: research

Challenges in Establishing a Transfusion Medicine Service: The Cleveland Clinic Abu Dhabi Experience.
CONCLUSIONS: - Although laboratory and clinical staff are knowledgeable in care delivery, it is always a learning experience to establish a new system because of the natural tendency of resorting to previous practices and resistance to new approaches. PMID: 30102069 [PubMed - as supplied by publisher]
Source: Archives of Pathology and Laboratory Medicine - August 13, 2018 Category: Laboratory Medicine Authors: Algora M, Grabski G, Batac-Castro AL, Gibbs J, Chada N, Humieda S, Ahmad S, Anderson P, Figueroa PI, Mirza I, AbdelWareth L Tags: Arch Pathol Lab Med Source Type: research

Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care.
CONCLUSIONS.—: Needle biopsy adequacy can be improved by recognizing the importance of this diagnostic tool by promoting common criteria for needle biopsy adequacy; by optimizing needle biopsy procedural technique, technologies, clinical practice, professional education, and quality assurance; and by bundling biopsy procedure costs with downstream diagnostic modalities to provide better accountability and incentives to improve the diagnostic process. PMID: 31100015 [PubMed - as supplied by publisher]
Source: Archives of Pathology and Laboratory Medicine - May 16, 2019 Category: Laboratory Medicine Authors: Pritzker KPH, Nieminen HJ Tags: Arch Pathol Lab Med Source Type: research

Preanalytics and Precision Pathology: Pathology Practices to Ensure Molecular Integrity of Cancer Patient Biospecimens for Precision Medicine.
Abstract Biospecimens acquired during routine medical practice are the primary sources of molecular information about patients and their diseases that underlies precision medicine and translational research. In cancer care, molecular analysis of biospecimens is especially common because it often determines treatment choices and may be used to monitor therapy in real time. However, patient specimens are collected, handled, and processed according to routine clinical procedures during which they are subjected to factors that may alter their molecular quality and composition. Such artefactual alteration may skew data...
Source: Archives of Pathology and Laboratory Medicine - July 21, 2019 Category: Laboratory Medicine Authors: Compton CC, Robb JA, Anderson MW, Berry AB, Birdsong GG, Bloom KJ, Branton PA, Crothers JW, Cushman-Vokoun AM, Hicks DG, Khoury JD, Laser J, Marshall CB, Misialek MJ, Natale KE, Nowak JA, Olson D, Pfeifer JD, Schade A, Vance GH, Walk EE, Yohe SL Tags: Arch Pathol Lab Med Source Type: research

Philip T. Cagle, MD-Editor-in-Chief of the Archives of Pathology & Laboratory Medicine, 2005-2019.
Philip T. Cagle, MD-Editor-in-Chief of the Archives of Pathology & Laboratory Medicine, 2005-2019. Arch Pathol Lab Med. 2020 Feb;144(2):133-135 Authors: Allen TC Abstract • The Archives of Pathology & Laboratory Medicine was first published in 1926 as a specialty journal of the American Medical Association. It became the official journal of the College of American Pathologists in 1995. Under the dynamic leadership of its most recent editor-in-chief, Philip T. Cagle, MD, the Archives has dramatically increased its impact factor and become the most widely read general pathology journal. Dr....
Source: Archives of Pathology and Laboratory Medicine - January 29, 2020 Category: Laboratory Medicine Authors: Allen TC Tags: Arch Pathol Lab Med Source Type: research