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Total 35833 results found since Jan 2013.

Sports Injuries: Diagnosis, Prevention, Stem Cell Therapy, and Medical Sport Strategy.
Authors: Rahim S, Rahim F, Shirbandi K, Haghighi BB, Arjmand B Abstract Sports injuries diagnosis, prevention, and treatment are the most important issues of sports medicine. Fortunately, sports injuries are often treated effectively, and people with damage recover and return to the sport in a satisfactory condition. Meanwhile, many sports injuries and complications can be prevented. In general, sports injuries include acute or chronic injuries. Given increasing in popularity, sports medicine doctors use stem cells to treat a wide variety of sports injuries, including damage to tendons, ligaments, muscles, and cart...
Source: Advances in Experimental Medicine and Biology - December 13, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

TECHNIQUES Optogenetic Medicine: Synthetic Therapeutic Solutions Precision-Guided by Light
Gene- and cell-based therapies are well recognized as central pillars of next-generation medicine, but controllability remains a critical issue for clinical applications. In this context, optogenetics is opening up exciting new opportunities for precision-guided medicine by using illumination with light of appropriate intensity and wavelength as a trigger signal to achieve pinpoint spatiotemporal control of cellular activities, such as transgene expression. In this review, we highlight recent advances in optogenetics, focusing on devices for biomedical applications. We introduce the construction and applications of optogen...
Source: Cold Spring Harbor perspectives in medicine - September 2, 2019 Category: Research Authors: Ye, H., Fussenegger, M. Tags: Bioelectronic Medicine TECHNIQUES Source Type: research

PERSPECTIVES Bioelectronic Medicine: From Preclinical Studies on the Inflammatory Reflex to New Approaches in Disease Diagnosis and Treatment
Bioelectronic medicine is an evolving field in which new insights into the regulatory role of the nervous system and new developments in bioelectronic technology result in novel approaches in disease diagnosis and treatment. Studies on the immunoregulatory function of the vagus nerve and the inflammatory reflex have a specific place in bioelectronic medicine. These studies recently led to clinical trials with bioelectronic vagus nerve stimulation in inflammatory diseases and other conditions. Here, we outline key findings from this preclinical and clinical research. We also point to other aspects and pillars of interdiscip...
Source: Cold Spring Harbor perspectives in medicine - March 1, 2020 Category: Research Authors: Pavlov, V. A., Chavan, S. S., Tracey, K. J. Tags: Bioelectronic Medicine PERSPECTIVES Source Type: research

ESSAY Bioelectronic Medicine--Ethical Concerns
Bioelectronic medicine (BEM) offers exciting opportunities to treat diseases such as movement disorders and refractory inflammatory disease. The many variations of BEM allow for noninvasive aspects of treatment that might eliminate or reduce the need for pharmaceuticals; therefore, the term "electroceuticals" may be suitable. BEM has been effective for movement disorders and improvement of prosthetic devices. Based on this implication, there is an allowance to impact many focus areas that include but are not limited to autoimmune disease, sensory motor conditions, and neurological conditions. There are a wide array of ethi...
Source: Cold Spring Harbor perspectives in medicine - September 30, 2019 Category: Research Authors: Packer, S., Mercado, N., Haridat, A. Tags: Bioelectronic Medicine ESSAY Source Type: research

A Message for Young Authors: The Past 100 Years and Future of the Tohoku Journal of Experimental Medicine.
Source: The Tohoku Journal of Experimental Medicine - January 28, 2020 Category: Research Authors: The Past 100 Years and Future of the Tohoku Journal of Experimental Medicine. Tags: Tohoku J Exp Med Source Type: research

PERSPECTIVES Neural Control of Inflammation: Bioelectronic Medicine in Treatment of Chronic Inflammatory Disease
Inflammation is important for antimicrobial defense and for tissue repair after trauma. The inflammatory response and its resolution are both active processes that must be tightly regulated to maintain homeostasis. Excessive inflammation and nonresolving inflammation cause tissue damage and chronic disease, including autoinflammatory and cardiovascular diseases. An improved understanding of the cellular and molecular mechanisms that regulate inflammation has supported development of novel therapies for several inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease. Many of the specific anticyt...
Source: Cold Spring Harbor perspectives in medicine - March 1, 2020 Category: Research Authors: Eberhardson, M., Tarnawski, L., Centa, M., Olofsson, P. S. Tags: Bioelectronic Medicine PERSPECTIVES Source Type: research

Athlete's Heart and Left Heart Disease.
Authors: de Gregorio C, Di Nunzio D, Di Bella G Abstract Physical activity comprises all muscular activities that require energy expenditure. Regular sequence of structured and organized exercise with the specific purpose of improving wellness and athletic performance is defined as a sports activity.Exercise can be performed at various levels of intensity and duration. According to the social context and pathways, it can be recreational, occupational, and competitive. Therefore, the training burden varies inherently and the heart adaptation is challenging.Although a general agreement on the fact that sports practic...
Source: Advances in Experimental Medicine and Biology - March 14, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

Characteristics of Parents Who Feel a Lack of Communication with Coaches of Youth Sports
This study aimed to elucidate the characteristics of parents who feel a lack of communication with their children's coaches of youth sports. A cross-sectional study was conducted on parents of young athletes (n = 6,641) and multivariate logistic regression analyses were performed to assess factors related to parents' feeling of a lack of communication with their children's coaches. Among the respondents, 29.4% of parents felt a lack of communication with their children's coaches. The factors related to the parents' feeling were a shorter duration of their children playing the present sport, an absence of experience playing...
Source: The Tohoku Journal of Experimental Medicine - March 15, 2021 Category: Research Authors: Yutaka Yabe Yoshihiro Hagiwara Takuya Sekiguchi Haruki Momma Masahiro Tsuchiya Kenji Kanazawa Shinichirou Yoshida Eiji Itoi Ryoichi Nagatomi Source Type: research

Exercise and Endurance Sports Increase Arrhythmia and Heart Failure Risk in Carriers Of ARVD/C Mutation - 7/17/13
A Johns Hopkins study finds that healthy people who carry a genetic mutation for arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) are at much higher risk of developing the symptoms of the life-threatening heart disease if they participate in endurance sports and frequent exercise.
Source: Johns Hopkins Medicine News - July 18, 2013 Category: Research Source Type: news

An Overview on Sleep Medicine
Adv Exp Med Biol. 2022;1384:3-15. doi: 10.1007/978-3-031-06413-5_1.ABSTRACTSleep plays an important role in homeostasis, brain plasticity, clearance of neurotoxins, cognition, memory, concentration, performance, and the regulation of the temperature, endocrine and immunological systems. Insufficient, disorganized, and poor-quality sleep impacts performance, cognition, and safety, carries social and economic consequences and predisposes to obesity, excessive daytime sleepiness, fatigue, arterial hypertension, diabetes, stroke, coronary arterial disease, Alzheimer's disease, depression, and anxiety. Consequently, the search ...
Source: Advances in Experimental Medicine and Biology - October 10, 2022 Category: Research Authors: Alex Iranzo Source Type: research