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Classical swine fever in India: current status and future perspective
AbstractClassical swine fever (CSF) is a globally significant disease of swine caused by classical swine fever virus. The virus affects the wild boars and pigs of all age groups, leading to acute, chronic, late-onset or in-apparent course of the disease. The disease causes great economic loss to the piggery industry due to mortality, stunted growth, poor reproductive performance, and by impeding the international trade of pig and pig products. In India, CSF outbreaks are reported from most of the states wherever pig rearing is practiced and more frequently from northeast states. In spite of the highly devastating nature an...
Source: Tropical Animal Health and Production - May 4, 2018 Category: Veterinary Research Source Type: research

Survival of African swine fever virus (ASFV) in various traditional Italian dry-cured meat products
Publication date: Available online 29 November 2018Source: Preventive Veterinary MedicineAuthor(s): Stefano Petrini, Francesco Feliziani, Cristina Casciari, Monica Giammarioli, Claudia Torresi, Gian Mario De MiaAbstractA number of animal diseases can be transmitted to pigs via pork meat and pork products imported from infected areas. Therefore, feeding of swill to pigs is regulated or prohibited in many swine-rearing countries. African swine fever is one of the major porcine diseases recognized as significant in this transmission pathway. Assessment of disease risks associated with pork products requires knowledge about th...
Source: Preventive Veterinary Medicine - November 30, 2018 Category: Veterinary Research Source Type: research

Japanese Encephalitis Virus infection induces inflammation of swine testis through RIG-I—NF-ĸB signaling pathway
In this study, histopathological analysis and immunohistochemistry staining was performed on testis of JEV-infected boars, indicating that JEV could infect testicular cells and cause inflammatory changes in testis. In vitro assays reveal that primary swine testicular cells and swine testis (ST) cells are highly permissive to JEV and significant inflammatory response was shown during JEV infection. Mechanically, we found that JEV infection increases the expression of retinoic acid-inducible gene I (RIG-I) and activates transcription factor NF-κB. Production of pro-inflammatory cytokines was greatly reduced in JEV infected...
Source: Veterinary Microbiology - September 29, 2019 Category: Veterinary Research Source Type: research

Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans.
CONCLUSIONS: This study identifies evolutionarily conserved gene signatures and signaling pathways in a stage-specific manner that successfully distinguishes diabetes- and non-diabetes-associated atherosclerosis. These findings establish new molecular insights and therapeutic opportunities to address accelerated atherosclerotic lesion formation in diabetes. PMID: 33567868 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 11, 2021 Category: Cardiology Authors: Haemmig S, Hashemi Gheinani A, Zaromytidou M, Siasos G, Coskun AU, Cormier MA, Gross DA, Wara AKMK, Antoniadis A, Sun X, Sukhova GK, Welt F, Andreou I, Whatling C, Gan LM, Wikström J, Edelman ER, Libby P, Stone PH, Feinberg MW Tags: Arterioscler Thromb Vasc Biol Source Type: research

African Swine Fever Virus Induces STAT1 and STAT2 Degradation to Counteract IFN-I Signaling
African swine fever virus (ASFV) causes a serious disease in domestic pigs and wild boars and is currently expanding worldwide. No safe and efficacious vaccines against ASFV are available, which threats the swine industry worldwide. African swine fever virus (ASFV) is a complex dsDNA virus that displays multiple mechanisms to counteract the host innate immune response, whose efficacy might determine the different degrees of virulence displayed by attenuated and virulent ASFV strains. Here we report that infection with both virulent Arm/07/CBM/c2 and attenuated NH/P68 strains prevents interferon-stimulated gene (ISG) expres...
Source: Frontiers in Microbiology - August 26, 2021 Category: Microbiology Source Type: research

Development of a quadruple PCR-based gene microarray for detection of vaccine and wild-type classical swine fever virus, African swine fever virus and atypical porcine pestivirus
Classical swine fever (CSF), African swine fever (ASF), and atypical porcine pestivirus (APPV) are acute, virulent, and contagious viral diseases currently hampering the pig industry in China, which result in ...
Source: Virology Journal - November 29, 2022 Category: Virology Authors: Ying-ju Xia, Lu Xu, Jun-jie Zhao, Yuan-xi Li, Rui-zhi Wu, Xiang-peng Song, Qi-zu Zhao, Ye-bing Liu, Qin Wang and Qian-yi Zhang Tags: Research Source Type: research

Swine flu jab raises risk of narcolepsy in children
A swine flu jab which was given to hundreds of thousands of children carried an increased risk of developing the sleep disorder narcolepsy, research suggests.
Source: The Telegraph : Swine Flu A H1N1 - February 27, 2013 Category: Infectious Diseases Tags: 1 HEALTH Narcolepsy Source Type: news

Swine flu 'growing in resistance' to Tamiflu
Strains of swine flu that are resistant to the drug Tamiflu are spreading, say experts, raising more questions about a government decision to spend £500 million stockpiling it.
Source: Telegraph Health - March 18, 2013 Category: Consumer Health News Tags: h1n1 roche tamiflu resistance swine flu Source Type: news

Swine Flu, Bird Flu And Pandemic Vaccination
As the world prepares for what may be the next pandemic strain of influenza virus, in the H7N9 bird flu, a new UC Irvine study reveals that the 2009 H1N1 swine flu pandemic was deadliest for people under the age of 65, while those 65 and over had greater immunity due to previous exposure to similar viruses. Deaths from flu pandemics tend to skew younger than those from seasonal flu because of "antigenic recycling," or the fact that some parts of flu viruses have already made the rounds...
Source: Health News from Medical News Today - May 25, 2013 Category: Consumer Health News Tags: Swine Flu Source Type: news

Government set to u-turn over narcolepsy link to swine-flu jab
The Government is set to u-turn over the safety of a swine flu vaccine given to six million people in Britain and accept that on rare occasions it can trigger narcolepsy.    
Source: The Telegraph : Swine Flu A H1N1 - September 20, 2013 Category: Infectious Diseases Source Type: news

Swine flu deaths in 2009 much higher than previously estimated
A new study by over 60 researchers from 26 countries suggests that the number of people who died in the 2009 global H1N1 "swine flu" outbreak is much higher than official figures show.Writing in PLOS Medicine, they estimate the total respiratory deaths worldwide to be up to 203,000, some 10 times higher than the World Health Organization (WHO) official total, which is based on lab-confirmed cases.When they added deaths by other causes exacerbated by H1N1, the figure was nearly double this amount, or over 20 times higher than the WHO lab-confirmed cases.
Source: Health News from Medical News Today - November 28, 2013 Category: Consumer Health News Tags: Swine Flu Source Type: news

Describing antimicrobial use and reported treatment efficacy in Ontario swine using the Ontario swine veterinary-based Surveillance program
The objective of this work was to retrospectively assess records received through the Ontario Swine Veterinary-based Surveillance program July 2007 -- July 2009 to describe and assess relationships between reported treatment failure, antimicrobial use, diagnosis and body system affected. Results: Antimicrobial use occurred in 676 records, 80.4% of all records recording treatment (840). The most commonly used antimicrobials were penicillin (34.9%), tetracyclines (10.7%) and ceftiofur (7.8%), and the use of multiple antimicrobials occurred in 141/676 records (20.9%). A multi-level logistic regression model was built to descr...
Source: BMC Veterinary Research - Latest articles - December 1, 2013 Category: Veterinary Research Authors: Shiona Glass-KaastraDavid PearlRichard Reid-SmithBeverly McEwenScott McEwenRocio AmezcuaRobert Friendship Source Type: research

Government set to u-turn over narcolepsy link to swine-flu jab
The Government is set to u-turn over the safety of a swine flu vaccine given to six million people in Britain and accept that on rare occasions it can trigger narcolepsy.
Source: The Telegraph : Swine Flu A H1N1 - September 20, 2013 Category: Infectious Diseases Source Type: news

Swine flu jab raises risk of narcolepsy in children
A swine flu jab which was given to hundreds of thousands of children carried an increased risk of developing the sleep disorder narcolepsy, research suggests.
Source: The Telegraph : Swine Flu A H1N1 - February 27, 2013 Category: Infectious Diseases Tags: 1 HEALTH Narcolepsy Source Type: news

Five Ways to Fight the Swine Flu
View the Swine Flu video here.   Winter in North America brings with it yearly uninvited guests- flu bugs- multiple strains of illness causing viruses just waiting for new bodies to infect.   The most common recommendation has been to protect yourself with a flu vaccine.  But with virtually all the US flu suddenly resistant to the leading antiviral Tamiflu, health officials are worried about where this could lead.  Here are some key guidelines you MUST know if you want to survive this year’s flu season.   How can you distinguish a cold from the flu? First understand that colds are minor infections of the nose and t...
Source: Dr. Donna, MedicineWoman - January 25, 2009 Category: Medical Scientists Authors: Dr. Donna Tags: breaking news Personal Health public health flu influenza pandemic prevention swine flu tamiflu treatment Source Type: blogs