Filtered By:
Condition: Meniere's Disease
This page shows you your search results in order of date.
Order by Relevance | Date
Total 176 results found since Jan 2013.
Meniere's disease: Pathogenesis, treatments, and emerging approaches for an idiopathic bioenvironmental disorder
Environ Res. 2023 Aug 28:116972. doi: 10.1016/j.envres.2023.116972. Online ahead of print.ABSTRACTMeniere's disease (MD) is a severe inner ear condition known by debilitating symptoms, including spontaneous vertigo, fluctuating and progressive hearing loss, tinnitus, and aural fullness or pressure within the affected ear. Prosper Meniere first described the origins of MD in the 1860s, but its underlying mechanisms remain largely elusive today. Nevertheless, researchers have identified a key histopathological feature called Endolymphatic Hydrops (ELH), which refers to the excessive buildup of endolymph fluid in the membrano...
Source: Environmental Research - August 30, 2023 Category: Environmental Health Authors: Masoud Mohseni-Dargah Zahra Falahati Christopher Pastras Khosro Khajeh Payal Mukherjee Amir Razmjou Sebastian Stefani Mohsen Asadnia Source Type: research
Types of Inheritance and Genes Associated with Familial Meniere Disease
AbstractMeniere disease (MD) is a rare disorder of the inner ear defined by sensorineural hearing loss (SNHL) associated with episodes of vertigo and tinnitus. The phenotype is variable, and it may be associated with other comorbidities such as migraine, respiratory allergies, and several autoimmune disorders. The condition has a significant heritability according to epidemiological and familial segregation studies. Familial MD is found in 10% of cases, the most frequently found genes beingOTOG,MYO7A, andTECTA, previously associated with autosomal dominant and recessive non-syndromic SNHL. These findings suggest a new hypo...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Single-cell immune profiling of Meniere Disease patients
CONCLUSION: Our results support a systemic inflammatory response in some MD patients that show a type 2 response with allergic phenotype, which could benefit from personalized IL-4 blockers.PMID:37178857 | DOI:10.1016/j.clim.2023.109632
Source: Clinical Immunology - May 13, 2023 Category: Allergy & Immunology Authors: Marisa Flook Alba Escalera-Balsera Paulina Rybakowska Lidia Frejo Angel Batuecas-Caletrio Juan C Amor-Dorado Andres Soto-Varela Marta Alarc ón-Riquelme Jose A Lopez-Escamez Source Type: research
Types of Inheritance and Genes Associated with Familial Meniere Disease
J Assoc Res Otolaryngol. 2023 Apr 6. doi: 10.1007/s10162-023-00896-0. Online ahead of print.ABSTRACTMeniere disease (MD) is a rare disorder of the inner ear defined by sensorineural hearing loss (SNHL) associated with episodes of vertigo and tinnitus. The phenotype is variable, and it may be associated with other comorbidities such as migraine, respiratory allergies, and several autoimmune disorders. The condition has a significant heritability according to epidemiological and familial segregation studies. Familial MD is found in 10% of cases, the most frequently found genes being OTOG, MYO7A, and TECTA, previously associa...
Source: Cell Research - April 6, 2023 Category: Cytology Authors: Alberto M Parra-Perez Jose A Lopez-Escamez Source Type: research
Vestibular migraine or Meniere's disease: a diagnostic dilemma
AbstractMeniere ’s disease (MD) represents one of the vertigo disorders characterized by triad symptoms (recurrent vertigo, fluctuating hearing loss, tinnitus or ear fullness). The diagnosis of MD relies on the accurate and detailed taking of medical history, and the differentiation between MD and vestibular migr aine (VM) is of critical importance from the perspective of the treatment efficacy. VM is a highly prevalent vertigo condition and its typical symptoms (headache, vestibular symptoms, cochlear symptoms) mimic those of MD. Furthermore, the misdiagnosis in MD and VM could lead to VM patients mistakenl y receiving ...
Source: Journal of Neurology - December 23, 2022 Category: Neurology Source Type: research
Long-term efficacy of dexamethasone treatment via tympanic antrum catheterization for intractable Meniere's disease
ConclusionDexamethasone treatment via TAC can effectively control vertigo attacks and improve related symptoms of intractable MD patients, providing valuable new insights into the treatment of MD.
Source: Frontiers in Neurology - December 2, 2022 Category: Neurology Source Type: research
Correlation Between Quantitative Value of Endolymphatic Hydrops and Hearing Threshold Using Magnetic Resonance Imaging
CONCLUSIONS: The degree of endolymphatic hydrops in Meniere's disease can be revealed and assessed by 3D-FLAIR MRI after intravenous administration of double doses of gadoterate meglumine. Clinical evaluation of endolymphatic hydrops in Meniere's disease can be assisted by low- and middle-tone hearing thresholds, thereby providing anatomical support for the clinical symptoms of Meniere's disease.PMID:36412145 | DOI:10.1177/00034894221134729
Source: The Annals of Otology, Rhinology, and Laryngology - November 22, 2022 Category: ENT & OMF Authors: Weidong Zhang Jiapei Xie Songbai Li Bo Zhang Source Type: research
