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Total 116 results found since Jan 2013.

The role of the medial geniculate body of the thalamus in the pathophysiology of tinnitus and implications for treatment
Brain Res. 2022 Jan 17:147797. doi: 10.1016/j.brainres.2022.147797. Online ahead of print.ABSTRACTTinnitus is an auditory sensation in the absence of actual external stimulation. Different clinical interventions are used in tinnitus treatment, but only few patients respond to available options. The lack of successful tinnitus treatment is partly due to the limited knowledge about the mechanisms underlying tinnitus. Recently, the auditory part of the thalamus has gained attention as a central structure in the neuropathophysiology of tinnitus. Increased thalamic spontaneous firing rate, bursting activity and oscillations, al...
Source: Brain Research - January 20, 2022 Category: Neurology Authors: Faris Almasabi Marcus L F Janssen Jana Devos Michelle Moerel Michael Schwartze Sonja A Kotz Ali Jahanshahi Yasin Temel Jasper V Smit Source Type: research

"Evaluating the efficacy of hearing aids for tinnitus therapy - A Positron Emission Tomography study"
Brain Res. 2021 Nov 15:147728. doi: 10.1016/j.brainres.2021.147728. Online ahead of print.NO ABSTRACTPMID:34793755 | DOI:10.1016/j.brainres.2021.147728
Source: Brain Research - November 18, 2021 Category: Neurology Authors: Patricia Simonetti Carla Rachel Ono Camila de Godoi Carneiro Rafay Ali Khan Somayeh Shahsavarani Fatima Husain Jeanne Oiticica Source Type: research

On the impairment of executive control of attention in chronic tinnitus: Evidence from the attention network test
Behav Brain Res. 2021 Jul 27:113493. doi: 10.1016/j.bbr.2021.113493. Online ahead of print.ABSTRACTSubjective, chronic tinnitus is a condition that is common in most populations. Whereas many individuals tend to habituate to tinnitus over time, for some their attention seems pathologically drawn towards the sensation. For this subgroup of individuals with severe tinnitus, dysfunctional executive attention has been suggested to be implicated in the failure to habituate. However, since most previous studies have used attention tests with low validity and specificity in this assessment, there is a need for further corroborati...
Source: Brain Research - July 30, 2021 Category: Neurology Authors: Martin Jensen Eva H üttenrauch Jochen M üller-Mazzotta Boris A Stuck Cornelia Weise Source Type: research

Investigating the relation between minimum masking levels and hearing thresholds for tinnitus subtyping
Prog Brain Res. 2021;263:81-94. doi: 10.1016/bs.pbr.2021.04.011. Epub 2021 May 20.ABSTRACTHeterogeneity of tinnitus imposes a challenge for its treatment. Identifying tinnitus subtypes might help to establish individualized diagnosis and therapies. The minimum masking level (MML) is a clinical tool defined as the minimum intensity of a masking sound required to cover tinnitus. Understanding the differences among masking patterns in patients could facilitate the task of subtyping tinnitus. Here, we studied the variability of hearing thresholds and MMLs among patients with tinnitus to identify tinnitus subgroups. A populatio...
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Jose L Santacruz Emile de Kleine Pim van Dijk Source Type: research

The spatial percept of tinnitus is associated with hearing asymmetry: Subgroup comparisons
In this study, data from two independent datasets were combined (n=833 adults, age ranging from 20 to 91 years, 404 males, 429 females) to investigate characteristics of subgroups with different tinnitus spatial perception focusing on hearing asymmetry. Three principle findings emerged. First, a hearing asymmetry variable emphasizing the maximum interaural difference most strongly discriminated unilateral from bilateral tinnitus. Merging lateralized bilateral tinnitus (perceived in both ears but worse in one side) with unilateral tinnitus weakened this relationship. Second, there was an association between unilateral tinni...
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Eleni Genitsaridi Theodore Kypraios Niklas K Edvall Natalia Trpchevska Barbara Canlon Derek J Hoare Christopher R Cederroth Deborah A Hall Source Type: research

Gender differentiates effects of acoustic stimulation in patients with tinnitus
Prog Brain Res. 2021;263:25-57. doi: 10.1016/bs.pbr.2021.04.010. Epub 2021 May 20.ABSTRACTGender constitutes a major factor to consider when tailoring subtype-based therapies for tinnitus. Previous reports showed important differences between men and women concerning basic perceptual tinnitus characteristics (i.e., laterality, frequency, tinnitus loudness) as well as psychological reactions linked to this condition. Therapeutic approaches based on acoustic stimulation involve processes beyond a pure masking effect and consist of sound presentation temporarily altering or alleviating tinnitus perception via residual and/or ...
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Marta Partyka Patrick Neff Timoth ée Bacri Jakob Michels Nathan Weisz Winfried Schlee Source Type: research

Advancing tinnitus research and researcher training: A case study review and future perspectives
Prog Brain Res. 2021;263:191-208. doi: 10.1016/bs.pbr.2021.04.007. Epub 2021 May 20.ABSTRACTTinnitus affects one in 10 people and for many significantly impairs quality of life. Whilst there has been a notable increase in tinnitus research funding and tinnitus-related scientific publications in recent years, this is not keeping pace with other disciplines such as hearing loss. Tinnitus research is less attractive to industry funders, in particular because the field lacks consensus on many topics, objective measures, and treatment success stories. There is a clear need for even more funding, better quality studies, increase...
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Dawn Hazle Axel Schiller Derek J Hoare Winfried Schlee Source Type: research

Using a visual analog scale (VAS) to measure tinnitus-related distress and loudness: Investigating correlations using the Mini-TQ results of participants from the TrackYourTinnitus platform
CONCLUSIONS: Mobile-based VAS seems to be an appropriate approach to utilize daily measurements of tinnitus-related distress.PMID:34243888 | DOI:10.1016/bs.pbr.2020.08.008
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Albi Dode Muntazir Mehdi R üdiger Pryss Winfried Schlee Thomas Probst Manfred Reichert Franz Hauck Michael Winter Source Type: research

Effects of ecological momentary assessment (EMA) induced monitoring on tinnitus experience: A multiple-baseline single-case experiment
CONCLUSION: Findings of this study corroborate that EMA assessment does not negatively affect tinnitus experience. On the contrary, participants may have improved. The underlying mechanism of improvements are still to be uncovered. Findings are limited to severely affected tinnitus sufferers at present.PMID:34243887 | DOI:10.1016/bs.pbr.2021.04.009
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Matheus P C G Lourenco Rilana F F Cima Johan W S Vlaeyen Source Type: research

High Definition transcranial Direct Current Stimulation (HD-tDCS) for chronic tinnitus: Outcomes from a prospective longitudinal large cohort study
CONCLUSIONS: The current study reported the effects of HD-tDCS in a large tinnitus population. HD-tDCS of the right DLPFC resulted in a significant improvement of the tinnitus perception, with a larger improvement for the female tinnitus patients.PMID:34243886 | DOI:10.1016/bs.pbr.2020.09.001
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Laure Jacquemin Griet Mertens Giriraj Singh Shekhawat Paul Van de Heyning Olivier M Vanderveken Vedat Topsakal Willem De Hertogh Sarah Michiels Jolien Beyers Julie Moyaert Vincent Van Rompaey Annick Gilles Source Type: research

Application of Latent Growth Curve modeling to predict individual trajectories during neurofeedback treatment for tinnitus
Prog Brain Res. 2021;263:109-136. doi: 10.1016/bs.pbr.2021.04.013. Epub 2021 May 20.ABSTRACTTinnitus is a heterogeneous phenomenon indexed by various EEG oscillatory profiles. Applying neurofeedback (NFB) with the aim of changing these oscillatory patterns not only provides help for those who suffer from the phantom percept, but a promising foundation from which to probe influential factors. The reliable attribution of influential factors that potentially predict oscillatory changes during the course of NFB training may lead to the identification of subgroups of individuals that are more or less responsive to NFB training....
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Constanze Riha Dominik G üntensperger Jessica Oschwald Tobias Kleinjung Martin Meyer Source Type: research

Modifiable lifestyle-related risk factors for tinnitus in the general population: An overview of smoking, alcohol, body mass index and caffeine intake
CONCLUSION: Our results contribute to quantifying the relationship between tinnitus and specific lifestyle-related risk factors, and we highlight some of the gaps and inconsistencies across published studies.PMID:34243884 | DOI:10.1016/bs.pbr.2021.04.005
Source: Brain Research - July 10, 2021 Category: Neurology Authors: Roshni Biswas Alessandra Lugo Eleni Genitsaridi Natalia Trpchevska Michael A Akeroyd Christopher R Cederroth Xiaoqiu Liu Winfried Schlee Werner Garavello Silvano Gallus Deborah A Hall Source Type: research

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