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Source: Hearing Research
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Total 170 results found since Jan 2013.
Asymmetric hearing thresholds are associated with hyperacusis in a large clinical population
Hear Res. 2023 Jul 15;437:108854. doi: 10.1016/j.heares.2023.108854. Online ahead of print.ABSTRACTHyperacusis is a debilitating auditory condition whose characterization is largely qualitative and is typically based on small participant cohorts. Here, we characterize the hearing and demographic profiles of adults who reported hyperacusis upon audiological evaluation at a large medical center. Audiometric data from 626 adults (age 18-80 years) with documented hyperacusis were retrospectively extracted from medical records and compared to an age- and sex-matched reference group of patients from the same clinic who did not r...
Source: Hearing Research - July 24, 2023 Category: Audiology Authors: Kelly N Jahn Daniel B Polley Source Type: research
A mouse model of repeated traumatic brain injury-induced hearing impairment: Early cochlear neurodegeneration in the absence of hair cell loss
CONCLUSIONS: We conclude that rTBI results in chronic auditory dysfunction via damage to the spiral ganglion which occurs in the absence of any reduction in hair cell number. This suggests early neuronal damage that may be caused by systemic mechanisms similar to those leading to the spread of neuronal death in the brain following TBI. This TBI-hearing loss model provides an important first step towards identifying therapeutic targets to attenuate damage to the auditory system following head injury.PMID:37364367 | DOI:10.1016/j.heares.2023.108832
Source: Hearing Research - June 26, 2023 Category: Audiology Authors: Courtney Penn Karthick Mayilsamy Xiao Xia Zhu Mark A Bauer Shyam S Mohapatra Robert D Frisina Subhra Mohapatra Source Type: research
Universal automated classification of the acoustic startle reflex using machine learning
Hear Res. 2022 Dec 15;428:108667. doi: 10.1016/j.heares.2022.108667. Online ahead of print.ABSTRACTThe startle reflex (SR), a robust, motor response elicited by an intense auditory, visual, or somatosensory stimulus has been widely used as a tool to assess psychophysiology in humans and animals for almost a century in diverse fields such as schizophrenia, bipolar disorder, hearing loss, and tinnitus. Previously, SR waveforms have been ignored, or assessed with basic statistical techniques and/or simple template matching paradigms. This has led to considerable variability in SR studies from different laboratories, and speci...
Source: Hearing Research - December 25, 2022 Category: Audiology Authors: Timothy J Fawcett Ryan J Longenecker Dimitri L Brunelle Joel I Berger Mark N Wallace Alex V Galazyuk Merri J Rosen Richard J Salvi Joseph P Walton Source Type: research
A liquid chromatography-mass spectroscopy-based untargeted metabolomic study of the rat cochlear nucleus at various stages of maturity
Hear Res. 2022 Nov 2;426:108645. doi: 10.1016/j.heares.2022.108645. Online ahead of print.ABSTRACTThe cochlear nucleus receives numerous inputs from auditory and nonauditory systems. This extensive innervation of the cochlear nucleus is involved in sound source localization and the integration of auditory signals with other sensory modalities. The dorsal cochlear nucleus may also have an important role in tinnitus. Although its gross anatomy and function have been extensively studied, the metabolome of the cochlear nucleus remains poorly understood, particularly at different stages of auditory maturity. Here, we present a ...
Source: Hearing Research - November 8, 2022 Category: Audiology Authors: Jun Tan Yue Li Dekun Gao Lianhua Sun Qiang Song Jun Yang Source Type: research
