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Total 683 results found since Jan 2013.

Effective treatment of refractory tinnitus by bilateral deep brain stimulation of the medial geniculate body of the thalamus: A case report
Tinnitus is the perception of a sound in the absence of an audible source. In 1.2% of the population, tinnitus has a large impact on several aspects of daily life and is often accompanied by depression, anxiety and sleep disturbances [1]. Tinnitus is associated with high costs of care, as well as societal and economic burden [2]. Despite the large impact on a person ’s life, treatment options remain limited. Deep brain stimulation (DBS) is considered a promising treatment for refractory tinnitus [3].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 31, 2023 Category: Neurology Authors: Jana V.P. Devos, Jasper V. Smit, Erwin L.J. George, Carsten Leue, Linda Ackermans, Yasin Temel, Marcus L.F. Janssen Source Type: research

Case report: Can cochlear implant stimulation lead to improved balance even after vestibular neurectomy?
DiscussionVestibular co-stimulation as a side effect of CI stimulation could not be the explanation in this case due to the ipsilateral vestibular neurectomy. It is more likely that the results can be attributed to the electrically restored auditory input, which serves as an external reference for maintaining balance and spatial orientation. In addition, this patient experienced disturbing tinnitus whenever her CI was deactivated. It is thus plausible that the tinnitus increased her cognitive load, which was already increased because of the BVP, leading to an increased imbalance in the absence of CI stimulation.
Source: Frontiers in Neurology - August 25, 2023 Category: Neurology Source Type: research

Development and internal validation of a prediction model for the presence of tinnitus in a Dutch population-based cohort
ConclusionWe developed and internally validated a prediction model on tinnitus presence in a multigenerational cohort of the Dutch general population. From the 24 candidate predictors, the final model included nine predictors.
Source: Frontiers in Neurology - August 3, 2023 Category: Neurology Source Type: research

Causes and outcomes of revision surgery in subjects with pulsatile tinnitus
DiscussionThe possibility of recurrence should be taken into account when performing surgical intervention in patients with PT. The likelihood of recurrence can be minimized through a comprehensive evaluation to identify possible multiple etiologies, and through the use of durable materials and appropriate surgical methods.
Source: Frontiers in Neurology - July 24, 2023 Category: Neurology Source Type: research

Effects of transcutaneous auricular vagus nerve stimulation paired with tones on electrophysiological markers of auditory perception
Transcutaneous auricular vagus nerve stimulation (taVNS) has been introduced as a non-invasive alternative to invasive vagus nerve stimulation (iVNS). While iVNS paired with tones has been highlighted as a potential effective therapy for the treatment of auditory disorders such as tinnitus, there is still scarce data available confirming the efficacy of non-invasive taVNS. Here, we assessed the effect of taVNS paired with acoustic stimuli on sensory-related electrophysiological responses.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 17, 2023 Category: Neurology Authors: Katharina S. Rufener, Christian Wienke, Alena Salanje, Aiden Haghikia, Tino Zaehle Source Type: research

Cluster and network analysis of non-headache symptoms in migraine patients reveals distinct subgroups based on onset age and vestibular-cochlear symptom interconnection
ConclusionUtilizing clustering and network analysis, we have identified two distinct non-headache symptom structures of migraine patients with early-onset age and late-onset age. Our findings suggest that the vestibular-cochlear symptoms may differ in the context of different onset ages of migraine patients, which may contribute to a better understanding of the pathology of vestibular-cochlear symptoms in migraine.
Source: Frontiers in Neurology - May 26, 2023 Category: Neurology Source Type: research

Endocannabinoid system components as potential neuroimmune therapeutic targets in tinnitus
Research interest in understanding tinnitus has increased severalfold in the last decade to find a cure for this auditory disorder. Hyperacusis can also accompany tinnitus, although the mechanisms involved in hyperacusis and tinnitus are different. Millions of people suffer from some degree of tinnitus with hearing loss. Tinnitus is believed to be a form of sensory epilepsy, spawning neuronal hyperactivity from the cochlear nucleus and inferior colliculus of the auditory brainstem region. Cannabis has been used for recreation, medicinal purposes, and served as an entheogen from time immemorial. With the current and increas...
Source: Frontiers in Neurology - May 25, 2023 Category: Neurology Source Type: research

Characteristics and prognostic analysis of simultaneous bilateral sudden sensorineural hearing loss
ConclusionPatients with Si-BSSNHL had mild deafness, elevated total and indirect bilirubin and homocysteine levels, and poorer prognosis than those with USSNHL. Audiogram curve type was linked to the therapeutic effect of Si-BSSNHL, and the sloping type was an independent risk factor for a poor prognosis in the right ear of Si-SSNHL.
Source: Frontiers in Neurology - May 5, 2023 Category: Neurology Source Type: research

Comparison of clinical features in patients with vestibular migraine and migraine
AbstractVestibular migraine (VM) is accepted as the most common cause of spontaneous episodic vertigo. In most patients, vestibular symptoms follow migraine headaches that begin earlier in life. The aim of this multicenter retrospective study was to find out the differences between migraine patients without any vestibular symptoms (MwoV) and VM patients and to delineate the specific clinical features associated with VM. MwoV and VM patients were compared regarding demographic features, migraine headache years, headache attack frequency, intensity, symptoms associated with headache and vertigo attacks, presence of menopause...
Source: Journal of Neurology - April 12, 2023 Category: Neurology Source Type: research

Bilateral Longitudinally Extensive Optic Perineuritis Post ‐COVID‐19 Presenting as “Idiopathic” Intracranial Hypertension: A Case Report
ConclusionThere is a growing association between demyelinating disorders and COVID-19 and COVID-19 vaccination, it is essential to recognize CSF abnormalities that are incompatible with a diagnosis of IIH, such as increased protein in our case, and may lead to an incorrect diagnosis.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Neuroimmunology - March 25, 2023 Category: Neurology Authors: Mohammad Aladawi, Daniel Crespo, Renfeng Xu, Rana Zabad, Amrita ‐Amanda Vuppala Tags: CASE REPORT Source Type: research

Onset-offset cortical auditory evoked potential amplitude differences indicate auditory cortical hyperactivity and reduced inhibition in people with tinnitus
CONCLUSIONS: Hypothesized reduced central inhibition and/or increased excitation in tinnitus participants was partially supported by a group difference in ΔP2 amplitude.SIGNIFICANCE: This was the first study to evaluate CAEP onset minus offset differences to investigate changes in central excitation/inhibition in individuals with tinnitus versus controls in matched groups.PMID:36963993 | DOI:10.1016/j.clinph.2023.02.164
Source: Clinical Neurophysiology - March 24, 2023 Category: Neurology Authors: Kenneth Morse Kathy R Vander Werff Source Type: research

Extremely rare cause of tinnitus: loop of the anterior inferior cerebellar artery originating from the internal carotid artery
Source: Acta Neurologica Belgica - March 23, 2023 Category: Neurology Source Type: research

Clinical features and prognosis of pediatric idiopathic sudden sensorineural hearing loss: A bi-center retrospective study
ConclusionsThe present study showed that accompanying tinnitus, the severity of initial hearing loss, the time elapse and the audiogram configuration might be related to the prognosis of pediatric SSNHL. Meanwhile, the presence of vertigo, lower lymphocytes and higher PLR were associated with worse severity.
Source: Frontiers in Neurology - March 15, 2023 Category: Neurology Source Type: research