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Specialty: Cancer & Oncology

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Total 115 results found since Jan 2013.

Mind-Body Therapies in the Management of Otolaryngologic Disease: A State-of-the-Art Review of Randomized Controlled Trials
CONCLUSION: RCTs of MBTs, including breathing exercises (4), aromatherapy (2), biofeedback (2), meditation, (2), and yoga (2), have been studied in several otolaryngologic conditions, including septoplasty/rhinoplasty (3), head and neck cancer (2), facial palsy (2), and tinnitus (2). Most studies were of moderate risk of bias on appraisal, and each MBT studied was found to significantly reduce subjective and objective distress associated with the otolaryngologic condition in question.IMPLICATIONS FOR PRACTICE: Despite a paucity of strong evidence supporting the universal use of MBTs, our review suggests that MBTs are cost-...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Dhruv S Kothari Chad A Nieri Zachary G Tanenbaum Lauren A Linker Sanjeet V Rangarajan Source Type: research

Fractionated Stereotactic Radiotherapy compared to Stereotactic Radiosurgery for Vestibular Schwannoma in patients with type-2 Neurofibromatosis
CONCLUSION: In the NF2 population, FRT may yield worse control rates than SRS. Whenever possible, it is preferable to not fractionate treatment for these patients. FRT results, nevertheless, are still good. More and larger prospective trials are warranted.PMID:37657590 | DOI:10.1016/j.wneu.2023.08.110
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Geovanne Pedro Mauro Leila Maria Da R óz Vinicius de Carvalho Gico Eduardo Weltman Evandro C ésar de Souza Eberval Gadelha Figueiredo Manoel Jacobsen Teixeira Source Type: research

Cancers, Vol. 15, Pages 4365: Sex Differences in Vestibular Schwannoma
In conclusion, self-rated QoL in VS is significantly affected by sex and surgery. This should be taken into account when counseling VS patients regarding observation, radiotherapy, and surgery.
Source: Cancers - September 1, 2023 Category: Cancer & Oncology Authors: Kathrin Machetanz Sophie S. Wang Linda Oberle Marcos Tatagiba Georgios Naros Tags: Article Source Type: research

An Update on Temporal Bone Paragangliomas
Opinion statementTemporal bone paragangliomas (TBPs) are indolent, classically benign and highly vascular neoplasms of the temporal bone. There are two types of TBPs, tympanomastoid paragangliomas (TMPs) and tympanojugular paragangliomas (TJPs). The most common symptoms are hearing loss and pulsatile tinnitus. Diagnostic workup, besides conventional physical and laboratory examinations, includes biochemical testing of catecholamine and genetic testing of SDHx gene mutations as well as radiological examination. Although surgery is traditionally the mainstay of treatment, it is challenging due to the close proximity of tumor...
Source: Current Treatment Options in Oncology - August 9, 2023 Category: Cancer & Oncology Source Type: research

Trading mental and physical health in vestibular schwannoma treatment decision
ConclusionPhysical and mental health is significantly influenced by VS surgery. While PH might decrease after surgery, MH potentially increases when patient is cured. Practitioners should take MH into account before advising an incompletely VS treatment (e.g., subtotal resection, observation or radiosurgery).
Source: Frontiers in Oncology - June 26, 2023 Category: Cancer & Oncology Source Type: research

The relevance of ototoxicity induced by radiotherapy
The risk of ototoxicity, characterized by hearing impairment, tinnitus, or middle ear inflammation, is elevated in both child and adult cancer survivors who have undergone head-neck or brain radiation, or a co...
Source: Radiation Oncology - June 3, 2023 Category: Cancer & Oncology Authors: Yan Huang, Hong Zhou, Fenglan An, Aimei Zhao, Jian Wu, Meihua Wang and Judong Luo Tags: Research Source Type: research

Hearing screening and amplifier uptake results in a multidisciplinary head and neck cancer survivorship clinic
ConclusionsThe data from 1176 survivors of HNC seen by audiology over the past few years as part of the UPMC HNC Survivorship Clinic support the need for hearing management in this population to improve communication during and after the Survivorship Clinic visit.Implications for Cancer SurvivorsSurvivors of HNC have a high prevalence of greater than mild hearing loss and tinnitus (both issues known to negatively impact health-related communication and quality of life). This manuscript describes a hearing screening program within a Survivorship Clinic that identifies individuals in need of non-custom amplification during t...
Source: Journal of Cancer Survivorship - May 25, 2023 Category: Cancer & Oncology Source Type: research

Association Between Chronic Tinnitus and Brain-Derived Neurotrophic Factor Antisense RNA Polymorphisms Linked to the Val66Met Polymorphism in BDNF
In conclusion, four of the polymorphisms in BDNF-AS gene (rs955946, rs1488830, rs1519480, and rs10767658) are potential gene loci that may play a role in the auditory pathway and affect auditory performance.PMID:37230202 | DOI:10.1016/j.gene.2023.147507
Source: Cancer Control - May 25, 2023 Category: Cancer & Oncology Authors: Buse Yuksel Murat Dogan Olcay Boyacioglu Mustafa Sahin Seda Orenay-Boyacioglu Source Type: research

Proton Radiotherapy for Vestibular Schwannomas in Patients with NF2-Related Schwannomatosis: A Case Series
Conclusion: After PRT for VS, the majority of the NF2 patients in the cohort did not require additional therapy. Tumor and/or treatment-related cranial nerve deficits were common. This is at least partly explained by the use of PRT as a salvage treatment after surgery or bevacizumab, in the majority of cases. There remains the further opportunity to elucidate the efficacy and toxicity of proton radiotherapy as a primary treatment.PMID:36975476 | DOI:10.3390/curroncol30030263
Source: Current Oncology - March 28, 2023 Category: Cancer & Oncology Authors: Jules P J Douwes Kimberley S Koetsier Victor S van Dam Scott R Plotkin Frederick G Barker D Bradley Welling Jeroen C Jansen Erik F Hensen Helen A Shih Source Type: research