Scientists Report Creating the First Embryo With Human and Non-Human Primate Cells
In a ground-breaking experiment, researchers have successfully created the first human-monkey chimera. The work, published in the journal Cell, describes the the first embryo containing both human and monkey cells that was cultured for 20 days. Led by Juan Carlos Izpisua Belmonte, the study represents the culmination of decades of work in understanding early embryo development in non-human species, which Belmonte hopes will now apply to humans. But it is bound to raise serious ethical questions about the implications of combining human cells with those from a different species (even if it is a closely related one), and the...
Source: TIME: Health - April 15, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Source Type: news

Shape-shifting Ebola virus protein exploits human RNA to change shape
(La Jolla Institute for Immunology) The new study shows how one of Ebola virus's key proteins, VP40, uses molecular triggers in the human cell to transform itself into different tools for different jobs.
Source: EurekAlert! - Infectious and Emerging Diseases - April 14, 2021 Category: Infectious Diseases Source Type: news

A clue to how some fast-growing tumors hide in plain sight
(La Jolla Institute for Immunology) Viruses churn out genetic material in parts of the cell where it's not supposed to be. Cancer cells do too. A new study shows that a tumor-suppressor enzyme called DAPK3 is an essential component of a multi-protein system that senses misplaced genetic material in tumor cells, and slows tumor growth by activating the fierce-sounding STING pathway.
Source: EurekAlert! - Cancer - March 25, 2021 Category: Cancer & Oncology Source Type: news

Namibia: Katutura Hospital Beds Get Facelift Courtesy of Firstrand Namibia Hope Fund
[Namibia Economist] FirstRand Namibia Hope fund's donation of N$357,400 for spare parts, saw repair work on 52 Stiegmeyer beds at the Intermediate Hospital Katutura commence last week.
Source: AllAfrica News: Health and Medicine - March 2, 2021 Category: African Health Source Type: news

David Julius and Ardem Patapoutian win the Frontiers of Knowledge Award in Biomedicine
(BBVA Foundation) The BBVA Foundation Frontiers of Knowledge Award in Biology and Biomedicine has gone in this thirteenth edition to David Julius, from the University of California, San Francisco, and Ardem Patapoutian, from the Scripps Institute, La Jolla (United States), " for identifying the receptors that enable us to sense temperature, pain and pressure. "
Source: EurekAlert! - Biology - January 27, 2021 Category: Biology Source Type: news

T cells can mount attacks against many SARS-CoV-2 targets--even on new virus variant
(La Jolla Institute for Immunology) A new study led by scientists at La Jolla Institute for Immunology (LJI) suggests that T cells try to fight SARS-CoV-2 by targeting a broad range of sites on the virus--beyond the key sites on the virus's spike protein. By attacking the virus from many angles, the body has the tools to potentially recognize different SARS-CoV-2 variants.
Source: EurekAlert! - Infectious and Emerging Diseases - January 27, 2021 Category: Infectious Diseases Source Type: news

A closer look at T cells reveals big differences in mild vs. severe COVID-19 cases
(La Jolla Institute for Immunology) A big question on people's minds these days: how long does immunity to SARS-CoV-2 last following infection? Now a research team from La Jolla Institute for Immunology (LJI), The University of Liverpool and the University of Southampton has uncovered an interesting clue. Their new study suggests that people with severe COVID-19 cases may be left with more of the protective 'memory' T cells needed to fight reinfection.
Source: EurekAlert! - Biology - January 21, 2021 Category: Biology Source Type: news

Paris' famous Champs- Élysées set for green transformation
One of the most famous avenues in Paris, the Champs-Élysées, is set for a facelift that will see it transformed into a green,...
Source: Reuters: Health - January 11, 2021 Category: Consumer Health News Source Type: news

Protective immunity against SARS-CoV-2 could last eight months or more
(La Jolla Institute for Immunology) The findings, based on analyses of blood samples from 188 COVID-19 patients, suggest that responses to the novel coronavirus, SARS-CoV-2, from all major players in the " adaptive " immune system, which learns to fight specific pathogens, can last for at least eight months after the onset of symptoms from the initial infection.
Source: EurekAlert! - Infectious and Emerging Diseases - January 6, 2021 Category: Infectious Diseases Source Type: news

New 3D maps reveal inner workings of immune cell gene expression
(La Jolla Institute for Immunology) The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. Researchers have created 3D maps of how enhancer sequences and genes interact in several types of immune cells. Their new study in Nature Genetics opens the door to understanding individual risk for diseases from asthma to cancer.
Source: EurekAlert! - Medicine and Health - December 21, 2020 Category: International Medicine & Public Health Source Type: news

Despite COVID-19 pandemic first patient undergoes new personalized immunotherapy
(University of California - San Diego) Bernard Thurman was referred to a personalized cancer therapy trial at Moores Cancer Center at UC San Diego Health, a collaboration with the La Jolla Institute for Immunology, the trial employs a patient's immune cells -- specifically tumor infiltrating lymphocytes (TIL) -- to destroy cancer cells.
Source: EurekAlert! - Cancer - December 10, 2020 Category: Cancer & Oncology Source Type: news

Researchers discover new particle in the blood of septic patients
(La Jolla Institute for Immunology) Researchers at La Jolla Institute for Immunology (LJI) have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.
Source: EurekAlert! - Medicine and Health - December 4, 2020 Category: International Medicine & Public Health Source Type: news

COVID-19 Immunity May Last Years After Recovery, New Study Finds
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 18, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Covid-19 Boston, MA Health Healthcare Status News Syndicated Local Coronavirus Source Type: news

Study suggests coronavirus immunity could last for months to years
Researchers at La Jolla Institute found COVID-19 immune cell levels slowly start to decline in the months following infection but sufficient amounts linger to block re-infection - perhaps for years.
Source: the Mail online | Health - November 18, 2020 Category: Consumer Health News Source Type: news

Immunity to the Coronavirus May Last Years, New Data Hint
Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported.
Source: NYT Health - November 17, 2020 Category: Consumer Health News Authors: Apoorva Mandavilli Tags: Immune System Coronavirus (2019-nCoV) Antibodies Vaccination and Immunization SARS (Severe Acute Respiratory Syndrome) your-feed-science La Jolla (Calif) Source Type: news

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