'Smart' bacteria remodel their genes to infect our intestines
(The Hebrew University of Jerusalem) How pathogens establish themselves in our gut is poorly understood. Now, researchers have described how bacteria sense their host and tailor their gene expression to cause disease. These findings may lead to the development of new strategies to combat bacterial infection.
Source: EurekAlert! - Infectious and Emerging Diseases - February 22, 2017 Category: Infectious Diseases Source Type: news

Report Homer1a drives homeostatic scaling-down of excitatory synapses during sleep
Sleep is an essential process that supports learning and memory by acting on synapses through poorly understood molecular mechanisms. Using biochemistry, proteomics, and imaging in mice, we find that during sleep, synapses undergo widespread alterations in composition and signaling, including weakening of synapses through removal and dephosphorylation of synaptic AMPA-type glutamate receptors. These changes are driven by the immediate early gene Homer1a and signaling from group I metabotropic glutamate receptors mGluR1/5. Homer1a serves as a molecular integrator of arousal and sleep need via the wake- and sleep-promoting n...
Source: ScienceNOW - February 2, 2017 Category: Science Authors: Graham H. Diering Source Type: news

Remembering where to get high
Addiction-related memories are exceptionally strong and stable, suggesting that addictive drugs remodel the brain ’s circuitry in a prominent and lasting way. In the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction-related behavior. Where as neuronal remodeling in the NAc explains a wide range of addictive behaviors, it is not required for all of them, according to a study.
Source: ScienceDaily Headlines - January 11, 2017 Category: Science Source Type: news

GraceMed purchasing property for Topeka clinic
GraceMed Health Clinic will purchase a former Dillons grocery store to house a community health center in Topeka. The Topeka Capital-Journal i s reporting Wichita-based GraceMed plans to remodel the site to create a new home for its Capitol Family Clinic in the central part of Topeka. GraceMed will conduct a capital campaign next year to raise $2.1 million toward renovation costs, according to the Capital-Jo urnal report. This summer, GraceMed took over management of the two Shawnee County Community…
Source: bizjournals.com Health Care:Biotechnology headlines - December 29, 2016 Category: Biotechnology Authors: Josh Heck Source Type: news

Fractures and Bone Remodeling in Children
In conclusion, fractures in children usually remodel. The x-ray may not look good, but 6 months from the initial x-rays will look better. The family will need to be reassured that the majority of fractures in children remodel and the child's function will not be affected by the fracture of the little angulation that is noticed. For more information on bone healing, follow the links below: https://www.youtube.com/watch?v=GPqe09FyPMU https://www.youtube.com/watch?v=oQSXeR8i4A8 https://www.youtube.com/watch?v=JRc5Tss-RFI https://www.youtube.com/watch?v=5DjZjAR_hG4 https://www.youtube.com/watch?v=TYNGyZrUXEk For information...
Source: Healthy Living - The Huffington Post - December 13, 2016 Category: Consumer Health News Source Type: news

Sanovas launches SinuGeniX sinus treatment subsidiary
Sanovas recently announced the launch of SinuGeniX, a wholly-owned subsidiary focused on treating chronic sinusitis with the company’s RegENT sinus treatment system. The newly-launched subsidiary won’t just supply a single tool for treating chronic sinusitis, which affects over 28 million Americans, but a suite of technologies, Sanovas CEO and system co-inventer Larry Gerrans told MassDevice.com in an interview. “I wanted to create the tool belt, not just the tool. We’ve created a number of very complimentary tools that will improve physicians access and imaging along with the treatment procedure and m...
Source: Mass Device - December 7, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Catheters Otolaryngology Ear, Nose & Throat Sanovas Source Type: news

St. Christopher's unveils revamped infusion therapy clinic
St. Christopher ’s Hospital for Children completed a $350,000 renovation project to provide new space for its oncology infusion therapy clinic. The work at the Philadelphia medical center began after Pepperidge Farm awarded a $30,000 grant to Go4theGoal, a South Jersey pediatric cancer organization, to remodel t he play area in the Oncology Infusion Clinic at St. Christopher’s. Go4theGoal’s leadership decided it wasn’t enough to renovate only the play area, and decided to fund an effort to…
Source: bizjournals.com Health Care:Biotechnology headlines - December 5, 2016 Category: Biotechnology Authors: John George Source Type: news

Public Health: A Trump Pick, and Why Indiana ’ s Strict Medicaid Rules Could Spread
Donald Trump ’ s nomination of Seema Verma suggests states will be given more power to remodel their Medicaid programs.
Source: NYT Health - December 1, 2016 Category: Consumer Health News Authors: MARGOT SANGER-KATZ Tags: Medicaid Seema Verma Health Insurance and Managed Care Patient Protection and Affordable Care Act (2010) United States Politics and Government Indiana Source Type: news

Clavicle Fractures in Children
A fractured clavicle in children usually heals with a small bump and will remodel in time. The clavicle is the first bone to ossify. The shaft of the clavicle ossifies in membrane and not in cartilage from the two primary ossification centers (Figure 1). Clavicle Fracture Types 95% of birth related injuries involve the clavicle. A clavicle birth fracture is usually associated with breach delivery and large babies. The fracture may cause pseudoparalysis. The doctor will need to rule out a brachial plexus injury. The reflexes remain intact following an isolated clavicle fracture. Clavicle Fractures in Children Ab...
Source: Healthy Living - The Huffington Post - November 23, 2016 Category: Consumer Health News Source Type: news

Why Opioids Can Stop Working
By Drs. David Niesel and Norbert Herzog The epidemic of opioid abuse and the resulting increases in overdoses and deaths have been front and center in the news for quite some time. Now a little appreciated effect called hyperalgesia, an increased sensitivity to pain, can make these drugs less effective for chronic pain leading people to take higher and higher doses seeking relief, increasing the chance of addiction. Opioids can actually prolong and amplify pain rather than relieving it. Opioids are pain relieving drugs that include hydrocodone, oxycodone, morphine, codeine and other related drugs including illegal ones s...
Source: Science - The Huffington Post - November 9, 2016 Category: Science Source Type: news

Editors' Choice Worms remodel immune responsiveness
Author: Caroline Ash
Source: ScienceNOW - November 3, 2016 Category: Science Authors: Caroline Ash Tags: Public Health Source Type: news

Intestinal cells 'remodel' in response to a fatty meal
(Carnegie Institution for Science) New work led by Carnegie's Steven Farber sheds light on how form follows function for intestinal cells responding to high-fat foods that are rich in cholesterol and triglycerides. It turns out that fatty foods cause the cells that line our intestines to do some interior remodeling.
Source: EurekAlert! - Biology - November 2, 2016 Category: Biology Source Type: news

Bonesupport raises $37m to support Cerament platform
Bonesupport said today it raised $37 million in anew round of equity and debt financing, with funds slated to support its Cerament platform of products. The oversubscribed equity round was led by Tellacq AB and joined by existing shareholders, including HealthCap, Lundbeckfond Ventures, Industrifonden, AP3 and Carl Westin, with the debt round being supported by Kreos Capital. “I am delighted that we have been able to complete this new financing to help us to execute our strategy to deliver the significant potential of our unique Cerament drug eluting osteoconductive/osteoinductive bioceramic platform. I am also plea...
Source: Mass Device - October 27, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Orthopedics Bonesupport Source Type: news

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