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Order by Relevance | Evaluating the impact of type 2 diabetes mellitus on cardiovascular risk in persons with metabolic syndrome using the UKPDS risk engine Bruxism Associated with Restless Limbs Syndrome (RLS): A Dopamine Responsive Movement Disorder (P02.063) Child Neurology: Diagnosis of Lambert-Eaton myasthenic syndrome in children Calorie Restriction Attenuates Cardiac Remodeling and Diastolic Dysfunction in a Rat Model of Metabolic Syndrome Metabolic Syndrome Helping People with Asperger’s Syndrome or Autism Find Work Lambert-Eaton syndrome IgG inhibits transmitter release via P/Q Ca2+ channels The Cockayne Syndrome Natural History (CoSyNH) study: clinical findings in 102 individuals and recommendations for care Long-term survival in paraneoplastic Lambert-Eaton myasthenic syndrome Embedding key word sign prompts in a shared book reading activity: The impact on communication between children with Down syndrome and their parents Differences in foot dimensions between children and adolescents with and without Down syndrome Disinfection behavior for COVID-19 in individuals with Down syndrome and caregivers' distress in Japan: a cross-sectional retrospective study
Conclusion: MS was more common in subjects with T2DM compared with controls (irrespective of the diagnostic criteria used) and MS appears to increase the risk of a coronary event in subjects with T2DM by threefold. Also from this study, MS did not appear to cause an additional increase in the risk of stroke in subjects with T2DM.Keywords: diabetes mellitus, metabolic syndrome, coronary heart disease, cardiovascular disease, UKPDS risk engine
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - September 15, 2015 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
CONCLUSIONS: These data support a strong association between RLS and bruxism, both movement disorders and parasomnias, and suggests that bruxism, in this population, may respond to treatment with DAs. Although retrospective, non-controlled, and unblinded, this study should enhance disease appreciation and encourage a blinded and placebo-controlled trial of DA for bruxism associated with RLS. Finally, the data suggest that bruxism may be a manifestation of RLS and is a dopamine-responsive movement disorder that should be well-known to, and treated by, neurologists in the future.Disclosure: Dr. Dickoff has received personal ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Dickoff, D. Tags: P02 Restless Legs Syndrome, Tourette Syndrome, and Dystonia Source Type: research
Conclusions:
There exists a need for consistent clinical criteria and electrodiagnostic testing for prompt diagnosis of LEMS in children. Prompt identification of LEMS will alert the physician to search for malignancy or another immune-mediated process.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Morgan-Followell, B., Reyes, E. d. l. Tags: Lambert-Eaton syndrome, Paraneoplastic syndrome, All Pediatric, All clinical neurophysiology RESIDENT AND FELLOW SECTION Source Type: research
Calorie restriction (CR) can modulate the features of obesity-related metabolic and cardiovascular diseases. We have recently characterized DahlS.Z-Leprfa/Leprfa (DS/obese) rats, derived from a cross between Dahl salt-sensitive and Zucker rats, as a new animal model of metabolic syndrome. DS/obese rats develop hypertension and manifest left ventricular remodeling and diastolic dysfunction, as well as increased cardiac oxidative stress and inflammation. We have now investigated the effects of CR on cardiac pathophysiology in DS/obese rats. DS/obese rats were fed either normal laboratory chow ad libitum or a calorie-restrict...
Source: Hypertension - October 16, 2013 Category: Cardiology Authors: Takatsu, M., Nakashima, C., Takahashi, K., Murase, T., Hattori, T., Ito, H., Murohara, T., Nagata, K. Tags: Metabolic Syndrome Source Type: research
An interview with an expert on employing people with Asperger's Syndrome or high-functioning autism.read more
Source: Psychology Today Work Center - May 9, 2014 Category: Psychiatry & Psychology Authors: Marty Nemko, Ph.D. Tags: Autism Work asperger syndrome ' s syndrome employing asperger Source Type: news
Conclusions:
These data provide direct evidence that LEMS IgG inhibits neurotransmitter release by acting on P/Q-type VGCCs.
Source: Neurology - February 9, 2015 Category: Neurology Authors: Spillane, J., Ermolyuk, Y., Cano-Jaimez, M., Lang, B., Vincent, A., Volynski, K. E., Kullmann, D. M. Tags: Autoimmune diseases, Lambert-Eaton syndrome, Paraneoplastic syndrome ARTICLE Source Type: research
Kate Pope, Katsuo Sugita, Susan M. White & Ian J. Wilson
Source: Genetics in Medicine - April 28, 2016 Category: Genetics & Stem Cells Authors: Brian T. WilsonZornitza StarkRuth E. SuttonSumita DandaAlka V. EkboteSolaf M. ElsayedLouise GibsonJudith A. GoodshipAndrew P. JacksonWee Teik KengMary D. KingEmma McCannToshino MotojimaJennifer E. MurrayTaku OmataDaniela PilzKate PopeKatsuo SugitaSusan M. Tags: cerebro-oculofacioskeletal syndrome Cockayne syndrome CSA (ERCC8) CSB (ERCC6) Source Type: research
Conclusions:
Improved SCLC tumor survival seen in patients with LEMS and SCLC may not be due solely to lead time bias, given that survival advantage remains after allowing for other prognostic factors and that the same degree of survival advantage is not seen in patients with paraneoplastic neurologic syndromes other than LEMS presenting before SCLC diagnosis.
Source: Neurology - April 3, 2017 Category: Neurology Authors: Maddison, P., Gozzard, P., Grainge, M. J., Lang, B. Tags: Lambert-Eaton syndrome, Paraneoplastic syndrome ARTICLE Source Type: research
CONCLUSIONS & IMPLICATIONS: This study shows that the simple act of embedding key word signs into commercially available books, during shared book reading between parents and young children with Down syndrome, positively affects children's participation (initiation and attention) and use of KWS. The use of KWS as a core shared book reading technique may therefore be a fruitful avenue to facilitate growth in the language abilities of young children with Down syndrome.WHAT THIS PAPER ADDS: What is already known on this subject Most children with Down syndrome have significant speech and language difficulties, with relative s...
Source: International Journal of Language and Communication Disorders - December 31, 2022 Category: Speech-Language Pathology Authors: Pauline Frizelle Rebecca Allenby Elizabeth Hassett Orlaith Holland Eimear Ryan Darren Dahly Ciara O'Toole Source Type: research
CONCLUSIONS: Children with Down syndrome have shorter, wider feet with greater girth and fifthtoe height measurements relative to children without Down syndrome. These findings have implications for footwear fit and the manufacturing of population-specific footwear.IMPLICATIONS FOR REHABILITATIONFootwear-fitting issues arise as a result of the unique foot shape of children with Down syndrome.There are substantial variations in the foot shape of children with and without Down syndrome.Children with Down syndrome require wider, deeper footwear at a given length to accommodate their foot dimensions.These findings have implica...
Source: Disability and Rehabilitation - March 11, 2021 Category: Rehabilitation Authors: Nirmeen M Hassan Andrew K Buldt Nora Shields Karl B Landorf Hylton B Menz Shannon E Munteanu Source Type: research
This study investigated the disinfection behaviors of individuals with Down syndrome and their caregivers' stress. A cross-sectional retrospective survey was conducted in October 2020. Caregivers of children and adults with Down syndrome were administered questionnaires including measures for practiced disinfection behavior in children, caregiver's child-related stress, and psychological distress. About half of the respondents' children practiced hand hygiene and mask-wearing behaviors, while physical distancing was performed less frequently. Habitual practices in physical distancing are affected by intellectual function. ...
Source: Health Physics - May 31, 2022 Category: Physics Authors: Haruo Fujino Minori Itai Source Type: research
