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Multicomponent cyclization with azides to synthesize N-heterocycles
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB01115A, Review ArticleHong Guo, Bei Zhou, Jingjing Chang, Wenxu Chang, Jiyao Feng, Zhenhua Zhang Heterocyclic compounds, both naturally derived and synthetically produced, constitute a wide variety of biologically active and industrially important compounds. The synthesis and application of heterocyclic compounds have garnered significant attention... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 22, 2023 Category: Molecular Biology Authors: Hong Guo Source Type: research

Pd@GO catalyzed stereo- and regio-selective addition of arenes to alkynes and synthesis of coumarins via C-H functionalization
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB01237A, PaperLenida Kyndiah, Fillip Kumar Sarkar, Sushmita Gajurel, Rajib Sarkar, Jasha Momo H. Anal, Amarta Kumar Pal A stereo- and regio-selective addition of arenes to alkynes via C-H bond functionalization has been developed using palladium nanoparticles supported on graphite oxide (Pd@GO) as the reusable catalyst. The prepared... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 22, 2023 Category: Molecular Biology Authors: Lenida Kyndiah Source Type: research

Improve emission performance of benzoaphenoxazine in aqueous solution through Host-Guest interaction
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB01427D, CommunicationShu-Yi Li, Wenli Wang, Chang Wang, Ru Sun, Jian-Feng Ge To evaluate the contribution of Host-Guest chemistry in fluorescent enhancement under aqueous condition, two benzo[a]phenoxazine derivatives with adamantyl group were prepared. After they formed stable complexes with methyl- β-cyclodextrin, their emissions... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 22, 2023 Category: Molecular Biology Authors: Shu-Yi Li Source Type: research

Many Americans Frustrated in Search for Low-Cost COVID Boosters
FRIDAY, Sept. 22, 2023 -- Americans seeking out the new COVID boosters are finding themselves held back by insurance entanglements and supply delays. Some insurers have balked at covering the vaccines, with people arriving at shot appointments only...
Source: Drugs.com - Daily MedNews - September 22, 2023 Category: General Medicine Source Type: news

HEAL Initiative: Research to Increase Implementation of Substance Use Preventive Services (R61/R33 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-066 from the NIH Guide for Grants and Contracts. The importance of prevention in combatting the opioid crisis is clear identifying and implementing effective strategies to prevent the onset of opioid misuse and use disorder and reducing the need to treat disorders yields positive individual, societal, and financial benefits. In 2020, 9.5 million people aged 12 or older misused opioids in the past year (NSDUH, 2021), suggesting that there are millions of people whose trajectories could have been changed, had they been exposed to an effective prevention strategy. Currently funded HEAL studies a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 22, 2023 Category: Research Source Type: funding

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients
Condition: ALSFTD Interventions: Dietary Supplement: Probiotic; Dietary Supplement: Placebo Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Lallemand Health Solutions Not yet recruiting
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

Care Transitions App for Patients With Multiple Chronic Conditions
Conditions: Heart Failure; Congestive Heart Failure; Diabetes; Diabetes Mellitus; Chronic Kidney Diseases Intervention: Behavioral: Care Transitions App Sponsors: Brigham and Women's Hospital; Agency for Healthcare Research and Quality (AHRQ) Not yet recruiting
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

Effect of Aerobic Training vs Balance Training on Fatigue Symptom in Multiple Sclerosis Patient (FATI-gate)
Condition: Multiple Sclerosis Interventions: Other: Aerobic training; Other: Balance training Sponsor: Istituto Auxologico Italiano Completed
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

Mezigdomide Plus Ixazomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma
Condition: Relapsed and Refractory Multiple Myeloma Interventions: Drug: Mezigdomide; Drug: Ixazomib; Drug: Dexamethasone Sponsors: Kathleen Dorritie; Bristol-Myers Squibb Not yet recruiting
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

CRACK-TARGET 1: ÉTUDE DESCRIPTIVE DE LA SENSIBILISATION COMPORTEMENTALE OBSERVÉE et ATTENTES
Condition: Cocaine Use Disorder Interventions: Behavioral: Observation of behavior and search of biomarkers with 3 blood tests.3 weeks wearing an actimeter; Biological: 3 blood tests Sponsors: Assistance Publique - Hôpitaux de Paris; Institut National de la Santé Et de la Recherche Médicale, France Not yet recruiting
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

A Phase I/II Clinical Study of LBL-034 in Patients With Relapsed/Refractory Multiple Myeloma
Condition: Relapsed/Refractory Multiple Myeloma Intervention: Drug: LBL-034 for Injection Sponsor: Nanjing Leads Biolabs Co.,Ltd Not yet recruiting
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

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