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Physical Activity Slows the Consequences of Aging
We live in a world in which most people do not undertake anywhere near the level of physical activity that is optimal. Thus adding greater physical activity as a lifestyle choice appears very beneficial. There is a great deficiency, one that has serious consequences to health, and fixing that deficiency is touted as a successful intervention. But in reality, the situation is one in which most people harm their long term health through a form of self-neglect. This era of cheap calories and comfort is a time of vast benefits for humanity - but it has a few downsides, and this is one of them. This meta-analysis showe...
Source: Fight Aging! - May 12, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

11 Health ’s Free Virtual Support Platform for Chronic Digestive Disease Patients During COVID Pandemic: Interview with Michael Seres, Founder and CEO
11 Health, a medtech company based in the UK and California, has offered 12 weeks of free access to the Alfred SmartCare Platform, which allows for virtual peer and nursing support for patients with severe chronic digestive disorders, such as inflamm...
Source: Medgadget - April 27, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Public Health Telemedicine Source Type: blogs

Fight Aging! Newsletter, April 13th 2020
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training. From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - April 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weight-loss drug Belviq recalled
In February, the manufacturer of the weight-loss medication lorcaserin (Belviq, Belviq XR) voluntarily withdrew the drug from the US market at the request of the FDA. This was a result of emerging data showing that people who had taken the drug as part of a large clinical trial had an increased occurrence of cancer five years later. What were the findings about Belviq, and why did this information come to light now? Lorcaserin was approved by the FDA in 2012. As part of the approval process, the FDA reviewed a series of clinical trials that looked at its effects on weight and its safety profile, compared to a placebo. Base...
Source: Harvard Health Blog - April 9, 2020 Category: Consumer Health News Authors: Florencia Halperin, MD Tags: Diet and Weight Loss Drugs and Supplements Source Type: blogs

Fight Aging! Newsletter, March 23rd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - March 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Tracing the toxic fingerprint of a bacterium in our gut
Scientists have discovered a common type of bacteria which could contribute to colorectal cancer
Source: OnMedica Blogs - March 10, 2020 Category: General Medicine Source Type: blogs

10 Ways Technology Is Changing Healthcare
The future of healthcare is shaping up in front of our very eyes with advances in digital technologies, such as artificial intelligence, VR/AR, 3D-printing, robotics or nanotechnology. We have to familiarize with the latest developments in order to be able to control technology and not the other way around. The future of healthcare lies in working hand-in-hand with technology and healthcare workers have to embrace emerging technologies in order to stay relevant in the coming years. Be bold, curious and informed! Are you afraid that robots will take over the jobs of nurses, doctors and other healthcare professionals? Are y...
Source: The Medical Futurist - March 3, 2020 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing AI artificial intelligence augmented reality genetics Health Healthcare nanotechnology Personalized medicine pharma pharmacology robotics virtual reality wearables GC1 Source Type: blogs

Mayo Clinic ' s Web Site Contains a " Find Diseases and Conditions " Feature
Searching for reliable web sites that discuss the diagnosis of diseases can be a hit-or-miss proposition. The process is sometimes jokingly referred to as"consulting Dr. Google" (see:The precautions you should take before consulting ‘Dr. Google’). Regarding the use of lab tests for diagnosis, one of the best resources that I know is the ARUP LaboratoriesTest Directory. One word of caution here is that it's primarily designed to guide physicians in test ordering.The trend of providing information on the web about diseases for consumers continues. One example is the Mayo Clinic web site (see:Find Dise...
Source: Lab Soft News - February 28, 2020 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Testing Diagnostics Electronic Health Record (EHR) Healthcare Information Technology Healthcare Innovations Medical Consumerism Public Health Source Type: blogs

Fight Aging! Newsletter, February 10th 2020
In conclusion, the concept of an epigenetic clock is compelling, but caution should be taken in interpreting associations with age acceleration. Association tests of age acceleration should include age as a covariate. A Discussion of Recent Work on Allotopic Expression of Mitochondrial Genes at the SENS Research Foundation https://www.fightaging.org/archives/2020/02/a-discussion-of-recent-work-on-allotopic-expression-of-mitochondrial-genes-at-the-sens-research-foundation/ A paper published last month outlines recent progress on allotopic expression of mitochondrial genes carried out by the SENS Research ...
Source: Fight Aging! - February 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Mechanism by which Chronic Inflammation Spurs Cancer Metastasis
Chronic inflammation is a risk factor for cancer and cancer mortality. There are numerous reasons as to why this might be the case, some much more proven and settled than others, but the research here is focused on metastasis, the spread of cancerous cells throughout the body. Since cancer mortality is largely determined by whether or not a tumor progresses to the point of metastasis, we should not be surprised that researchers can identify mechanisms linking inflammation with metastasis. Dysregulated inflammation is recognized as one of the hallmarks of cancer and is involved in tumor initiation, progression, an...
Source: Fight Aging! - February 5, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Asinine, Backasswards Colonoscopy Insurance Rules Make Patients Decline Medically Necessary Testing
By HANS DUVEFELT, MD I’ve had several telephone calls in the last two weeks from a 40-year-old woman with abdominal pain and changed bowel habits. She obviously needs a colonoscopy, which is what I told her when I saw her. If she needed an MRI to rule out a brain tumor I think she would accept that there would be co-pays or deductibles, because the seriousness of our concern for her symptoms would make her want the testing. But because in the inscrutable wisdom of the Obama Affordable Care Act, it was decided that screening colonoscopies done on people with no symptoms whatsoever are a freebie, whereas colonosco...
Source: The Health Care Blog - January 27, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Colonoscopy Hans Duvefelt Health insurance Source Type: blogs

Fight Aging! Newsletter, January 27th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Asinine, Backasswards Colonoscopy Insurance Rules Make Patients Decline Medically Necessary Testing
By HANS DUVEFELT, MD I’ve had several telephone calls in the last two weeks from a 40-year-old woman with abdominal pain and changed bowel habits. She obviously needs a colonoscopy, which is what I told her when I saw her. If she needed an MRI to rule out a brain tumor I think she would accept that there would be co-pays or deductibles, because the seriousness of our concern for her symptoms would make her want the testing. But because in the inscrutable wisdom of the Obama Affordable Care Act, it was decided that screening colonoscopies done on people with no symptoms whatsoever are a freebie, whereas colonosco...
Source: The Health Care Blog - January 24, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Colonoscopy Hans Duvefelt Health insurance Source Type: blogs

The truth about fatty liver
The majority of doctors will tell you that there is nothing you can do to reverse fatty liver and that health problems such as cirrhosis and liver failure may be in your future that they will address with the awful “solution” of liver transplant. The truth is the opposite: fatty liver is easily and readily reversible in virtually everybody, provided you take action before irreversible changes take place and are given the right information and tools. In this video, I discuss the three basic phenomena that drive fat deposition, liver damage, and inflammation that lead to this condition: Carbohydrate consumption ...
Source: Wheat Belly Blog - January 23, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora carbohydrates carbs Inflammation NAFLD nash triglycerides undoctored wheat belly Source Type: blogs

MR1 as a Broad Signature of Cancer, Suitable for T Cell Targeting
Meaningful progress towards the control of cancer, ending it as a major threat to life and health, will be led by programs that can produce very broadly applicable treatments. That means therapies that can be applied to many (or even all) cancers with minimal differences in configuration or need for further per-cancer development. There are hundreds of cancer subtypes, but only so many researchers, and only so much funding for research and development: development of highly specific therapies is just not an effective path forward. Examples of the most promising lines of work with broad application include the OncoSe...
Source: Fight Aging! - January 22, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs